{"id":1900,"date":"2022-01-01T11:52:24","date_gmt":"2022-01-01T03:52:24","guid":{"rendered":"http:\/\/oncolab.cn\/index.php\/2022\/01\/01\/%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac25%e7%ab%a0%ef%bc%9a%e6%84%9f%e6%9f%93%e5%92%8c%e7%96%ab%e8%8b%97\/"},"modified":"2022-01-01T11:52:24","modified_gmt":"2022-01-01T03:52:24","slug":"%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac25%e7%ab%a0%ef%bc%9a%e6%84%9f%e6%9f%93%e5%92%8c%e7%96%ab%e8%8b%97","status":"publish","type":"post","link":"http:\/\/oncolab.cn\/index.php\/2022\/01\/01\/%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac25%e7%ab%a0%ef%bc%9a%e6%84%9f%e6%9f%93%e5%92%8c%e7%96%ab%e8%8b%97\/","title":{"rendered":"\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c25\u7ae0\uff1a\u611f\u67d3\u548c\u75ab\u82d7"},"content":{"rendered":"
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\u65b0\u5e74\u65b0\u6c14\u8c61\uff0c\u795d\u5927\u5bb6\u5728\u65b0\u7684\u4e00\u5e74\u91cc\u4e07\u4e8b\u987a\u9042\uff0c\u8eab\u4f53\u5065\u5eb7~<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5bfc \u8bfb<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u672c\u7ae0\u8ba8\u8bba\u75c5\u539f\u4f53\u7528\u6765\u9003\u907f\u514d\u75ab\u76d1\u6d4b\u7684\u673a\u5236\u4ee5\u53ca\u4e09\u79cd\u4e3b\u8981\u7c7b\u578b\u7684\u75ab\u82d7\u662f\u5982\u4f55\u523a\u6fc0\u514d\u75ab\u53cd\u5e94\u7684\u3002\u672c\u7ae0\u4e2d\u7684BOX\u63d0\u4f9b\u4e86\u5173\u4e8e\u56db\u79cd\u91cd\u8981\u75ab\u82d7\u7684\u66f4\u591a\u8be6\u7ec6\u5185\u5bb9\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u751f\u7269\u4f53\u662f\u5982\u4f55\u9003\u907f\u514d\u75ab\u53cd\u5e94\u7684<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e3a\u4e86\u83b7\u5f97\u6210\u529f\uff0c\u6bcf\u79cd\u7c7b\u578b\u7684\u75c5\u539f\u4f53\u90fd\u8fdb\u5316\u51fa\u4e86\u4e0d\u540c\u7684\u9003\u907f\u514d\u75ab\u7cfb\u7edf\u76d1\u6d4b\u7684\u65b9\u5f0f\u3002Fig 25.1<\/span>\u603b\u7ed3\u4e86\u5176\u4e2d\u7684\u4e00\u4e9b\u5185\u5bb9\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5fae\u5c0fRNA\u75c5\u6bd2\uff0c\u5982\u6d41\u611f\u75c5\u6bd2(BOX 25.2<\/span>)\u548c\u827e\u6ecb\u75c5\u75c5\u6bd2(\u7b2c33\u7ae0<\/span>)\uff0c\u5b83\u4eec\u7684\u5c0f\u57fa\u56e0\u7ec4\u4e2d\u6ca1\u6709\u8db3\u591f\u7684\u5bb9\u91cf\u6765\u7f16\u7801\u6709\u52a9\u4e8e\u9003\u907f\u514d\u75ab\u53cd\u5e94\u3002\u7136\u800c\uff0cRNA\u57fa\u56e0\u7ec4\u7684\u4e00\u4e2a\u7279\u70b9\u662f\u5b83\u5bb9\u6613\u53d1\u751f\u7a81\u53d8\uff0c\u5c5e\u4e8eRNA\u75c5\u6bd2\u7684\u6297\u539f\u86cb\u767d\u4e0d\u65ad\u53d8\u5316\uff0c\u4ece\u800c\u9003\u907f\u514d\u75ab\u8bb0\u5fc6\u3002\u4f8b\u5982\u611f\u67d3HIV\u540e\uff0c\u53d7\u611f\u67d3\u7684\u5bbf\u4e3b\u5728\u77ed\u77ed\u51e0\u4e2a\u6708\u5185\u5c31\u4f1a\u51fa\u73b0\u8bb8\u591a\u4e0d\u540c\u7684\u6bd2\u682a\uff0c\u6d41\u611f\u75c5\u6bd2\u5728\u4eba\u7fa4\u4e2d\u7684\u53d8\u5f02\u901f\u5ea6\u6bd4\u5728\u4e2a\u4f53\u4e2d\u7684\u53d8\u5f02\u8981\u6162\u5f97\u591a\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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DNA\u75c5\u6bd2\u66f4\u5927\uff0c\u5728\u5b83\u4eec\u7684\u57fa\u56e0\u7ec4\u4e2d\u6709\u8eb2\u907f\u514d\u75ab\u53cd\u5e94\u7684\u57fa\u56e0\u3002\u4e00\u4e9bDNA\u75c5\u6bd2\uff0c\u5982\u75b1\u75b9\u75c5\u6bd2\u5bb6\u65cf\u7684\u6210\u5458\uff0c\u901a\u8fc7\u4e0b\u8c03MHC\u7684\u8868\u8fbe\u6765\u9003\u907f\u83b7\u5f97\u6027\u514d\u75ab\u53cd\u5e94\uff0c\u56e0\u6b64\u66f4\u9700\u8981\u5148\u5929\u514d\u75ab\u5e94\u7b54(\u5982NK\u7ec6\u80de)\u6765\u63a7\u5236\u3002\u4f46\u7531\u4e8e\u5148\u5929\u7cfb\u7edf\u6ca1\u6709\u514d\u75ab\u8bb0\u5fc6\uff0c\u56e0\u6b64\u5f88\u96be\u542f\u52a8\u5bf9\u75b1\u75b9\u75c5\u6bd2\u7b49\u75c5\u6bd2\u7684\u53cd\u5e94\uff0c\u4e5f\u5c31\u96be\u4ee5\u4fdd\u62a4\u4e2a\u4eba\u514d\u53d7\u611f\u67d3\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u7ec6\u83cc\u75c5\u539f\u4f53\u4f7f\u7528\u5404\u79cd\u65b9\u6cd5\u6765\u9003\u907f\u514d\u75ab\u7cfb\u7edf\u3002\u80ba\u708e\u94fe\u7403\u83cc\u548c\u55dc\u8840\u6746\u83cc\u901a\u8fc7\u4ea7\u751f\u591a\u7cd6\u835a\u819c\u6765\u9003\u907f\u5148\u5929\u514d\u75ab\u5e94\u7b54(\u8865\u4f53\u8c03\u7406\u548c\u541e\u566c)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u679d\u6746\u83cc\uff0c\u5982\u7ed3\u6838\u5206\u679d\u6746\u83cc\uff0c\u6709\u80fd\u963b\u6b62\u541e\u566c\u7ec6\u80de\u9176\u4f5c\u7528\u7684\u8721\u72b6\u5305\u88ab\u3002\u5b83\u4eec\u8fd8\u5206\u6ccc\u8fc7\u6c27\u5316\u6c22\u9176\uff0c\u4ee5\u6291\u5236\u547c\u5438\u6c27\u5316\u7206\u53d1<\/span>\u7684\u5f71\u54cd\u3002\u7b2c23\u7ae0<\/span>\u8ba8\u8bba\u4e86\u5de8\u566c\u7ec6\u80de\u5982\u4f55\u5728\u4e0d\u6740\u6b7b\u5206\u679d\u6746\u83cc\u7684\u60c5\u51b5\u4e0b\u63a7\u5236\u5b83\u4eec\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u674e\u65af\u7279\u83cc\u4f1a\u5f15\u8d77\u8111\u819c\u708e\uff0c\u5c24\u5176\u662f\u5728\u5b55\u5987\u4f53\u5185\u3002\u674e\u65af\u7279\u83cc\u5206\u6ccc\u674e\u65af\u7279\u83cc\u6eb6\u83cc\u7d20\uff0c\u5728\u541e\u566c\u4f53\u58c1\u4e0a\u7a7f\u5b54\u3002\u7136\u540e\u7ec6\u83cc\u53ef\u4ee5\u9003\u9038\u5230\u7ec6\u80de\u8d28\u4e2d\uff0c\u5728\u90a3\u91cc\u5b83\u4eec\u4e0d\u4f1a\u63a5\u89e6\u5230\u5728\u4ee3\u8c22\u7206\u53d1\u7684\u6709\u6bd2\u4ea7\u7269\u6216\u86cb\u767d\u6c34\u89e3\u9176\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig 25.1<\/span> \u5404\u79cd\u75c5\u539f\u4f53\u9003\u907f\u514d\u75ab\u7cfb\u7edf\u7684\u7b56\u7565<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u514d\u75ab\u673a\u5236<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u9664\u4e86\u4e0a\u4e00\u8282\u63d0\u5230\u7684\u4e00\u4e9b\u611f\u67d3(\u7ed3\u6838\u75c5\u3001HIV\u548c\u75b1\u75b9\u75c5\u6bd2\u611f\u67d3)\u5916\uff0c\u5927\u591a\u6570\u4e3b\u8981\u611f\u67d3\u90fd\u80fd\u591f\u88ab\u514d\u75ab\u7cfb\u7edf\u5b8c\u5168\u6e05\u9664\uff0c\u4ee5\u8fbe\u5230\u706d\u83cc\u7684\u514d\u75ab\u72b6\u6001\u3002\u6b64\u5916\uff0c\u514d\u75ab\u8bb0\u5fc6\u529b\u5f97\u5230\u53d1\u5c55\uff1b\u4e4b\u540e\u540c\u4e00\u75c5\u539f\u4f53\u518d\u6b21\u66b4\u9732\u5728\u514d\u75ab\u7cfb\u7edf\u4e2d\u4f1a\u5f15\u8d77\u9002\u5e94\u6027\u514d\u75ab\u7cfb\u7edf\u7684\u8bb0\u5fc6\u53cd\u5e94\uff0c\u4ece\u800c\u9632\u6b62\u611f\u67d3\u6216\u51cf\u8f7b\u75c7\u72b6\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u6bcd\u4f53\u6297\u4f53\u4e27\u5931\u540e\uff0c\u513f\u7ae5\u53ef\u80fd\u4f1a\u53d1\u751f\u4e00\u7cfb\u5217\u7684\u539f\u53d1\u611f\u67d3\uff0c\u540c\u65f6\u5f62\u6210\u6709\u6548\u7684\u514d\u75ab\u8bb0\u5fc6\u3002\u63a5\u79cd\u75ab\u82d7\u53ef\u4ee5\u4f5c\u4e3a\u521d\u6b21\u611f\u67d3\u7684\u66ff\u4ee3\u54c1\uff0c\u4f7f\u514d\u75ab\u8bb0\u5fc6\u5f97\u4ee5\u53d1\u5c55\uff0c\u800c\u4e0d\u4f1a\u51fa\u73b0\u6709\u75c7\u72b6\u7684\u521d\u6b21\u611f\u67d3\u3002\u75ab\u82d7\u5c31\u662f\u4e00\u4e2a\u6210\u529f\u7684\u4f8b\u5b50\uff1b\u5929\u82b1\u662f\u4e00\u79cd\u901a\u8fc7\u63a5\u79cd\u75ab\u82d7\u8fbe\u5230\u5b8c\u5168\u6839\u9664\u7684\u81f4\u547d\u611f\u67d3\u3002\u8bb8\u591a\u5176\u4ed6\u611f\u67d3\uff0c\u5982\u810a\u9ad3\u7070\u8d28\u708e\u3001\u767d\u5589\u548c\u767e\u65e5\u54b3\u4e5f\u5df2\u53d8\u5f97\u76f8\u5bf9\u7f55\u89c1\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u6211\u4eec\u8be6\u7ec6\u8ba8\u8bba\u75ab\u82d7\u4e4b\u524d\uff0c\u6211\u4eec\u9700\u8981\u4e86\u89e3\u88ab\u52a8\u514d\u75ab\u7597\u6cd5\uff0c\u5373\u9002\u5e94\u6027\u514d\u75ab\uff08\u901a\u5e38\u662f\u6297\u4f53\uff09\uff0c<\/span>\u5e38\u7528\u4e8e\u7ed9\u63a5\u89e6\u75c5\u539f\u4f53\u7684\u4eba\u63d0\u4f9b\u7684\u4fdd\u62a4\u6027\u6297\u4f53\uff0c\u5982\u7834\u4f24\u98ce(\u89c1BOX 30.2<\/span>)\u3002\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u65e2\u53ef\u4ee5\u8fdb\u884c\u88ab\u52a8\u514d\u75ab\u6cbb\u7597\u4ee5\u964d\u4f4e\u773c\u524d\u7684\u611f\u67d3\u98ce\u9669\uff0c\u4e5f\u53ef\u4ee5\u4f7f\u7528\u75ab\u82d7\u6765\u8bf1\u5bfc\u514d\u75ab\u8bb0\u5fc6\u5e76\u964d\u4f4e\u672a\u6765\u611f\u67d3\u7684\u98ce\u9669\uff0c\u6297\u5730\u9ad8\u8f9bFab\u7247\u6bb5(\u89c1BOX 4.2<\/span>)\u4e5f\u662f\u4e00\u79cd\u88ab\u52a8\u514d\u75ab\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e3b\u52a8\u514d\u75ab\u662f\u5728\u611f\u67d3\u6216\u75ab\u82d7\u5f62\u5f0f\u7684\u6297\u539f\u66b4\u9732\u4e8e\u514d\u75ab\u7cfb\u7edf\u540e\u4ea7\u751f\u7684\u3002\u7136\u540e\uff0c\u514d\u75ab\u8bb0\u5fc6\u53d1\u5c55\u907f\u514d\u4e2a\u4f53\u518d\u6b21\u611f\u67d3\u3002\u5728\u5404\u79cd\u7c7b\u578b\u548c\u6210\u5206\u7684\u75ab\u82d7(TABLE 25.1<\/span>)\u4e2d\uff0c\u6bcf\u4e00\u79cd\u90fd\u6709\u81ea\u5df1\u7684\u4f18\u7f3a\u70b9\u3002\u5927\u591a\u6570\u75ab\u82d7\u4f1a\u5bfc\u81f4\u6297\u4f53\u751f\u6210\uff0c\u6709\u4e9b\u75ab\u82d7\u4f1a\u5f15\u53d1T\u7ec6\u80de\u53cd\u5e94\u3002\u75ab\u82d7\u5f15\u53d1\u7684\u6297\u4f53\u53ef\u4ee5\u963b\u6b62\u75c5\u539f\u4f53\u4e0e\u9776\u7ec6\u80de\u7ed3\u5408\uff0c\u6216\u8005\u963b\u6b62\u75c5\u539f\u4f53\u91ca\u653e\u7684\u6bd2\u7d20\u7684\u4f5c\u7528\uff0c\u8fd9\u4e9b\u90fd\u662f\u4e2d\u548c\u6297\u4f53\u7684\u4f8b\u5b50\u3002\u6297\u4f53\u8fd8\u53ef\u4ee5\u6fc0\u6d3b\u8865\u4f53\uff0c\u523a\u6fc0\u541e\u566c\u548cNK\u7ec6\u80de\u4ecb\u5bfc\u7684\u6740\u4f24\u3002\u75ab\u82d7\u8bf1\u5bfc\u7684CD8+<\/sup>T\u7ec6\u80de\u53ef\u4ee5\u901a\u8fc7\u5206\u6ccc\u5e72\u6270\u7d20\u6765\u6291\u5236\u75c5\u6bd2\u590d\u5236\uff0c\u6216\u8005\u66f4\u5e38\u89c1\u7684\u662f\u901a\u8fc7\u6740\u6b7b\u53d7\u611f\u67d3\u7684\u7ec6\u80de\u6765\u6291\u5236\u75c5\u6bd2\u590d\u5236\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u672c\u7ae0\u4ecb\u7ecd\u4e86\u6bcf\u79cd\u75ab\u82d7\u7684\u8be6\u7ec6\u60c5\u51b5\u3002BOX 25.1<\/span>\u5230BOX 25.4<\/span>\u63d0\u4f9b\u4e86\u6709\u5173\u5929\u82b1\u3001\u767e\u65e5\u54b3\u3001\u6d41\u611f\u548c\u4e59\u578b\u809d\u708e\u75ab\u82d7\u7684\u66f4\u591a\u5177\u4f53\u4fe1\u606f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u75ab\u82d7\u7684\u79cd\u7c7b<\/span><\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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Table25.1<\/span> \u75ab\u82d7\u7684\u5206\u7c7b<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u6d3b\u75ab\u82d7<\/p>\n<\/section>\n

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\u6d3b\u75ab\u82d7\u662f\u6700\u65e9\u88ab\u53d1\u73b0\uff0c\u4e14\u73b0\u5728\u4ecd\u7136\u662f\u6700\u6709\u6548\u7684\u75ab\u82d7\uff1b\u4f8b\u5982\uff0c\u5929\u82b1\u548c\u810a\u9ad3\u7070\u8d28\u708e\u75ab\u82d7\u5c31\u662f\u6d3b\u75ab\u82d7\u3002\u6d3b\u75ab\u82d7\u4f7f\u7528\u7684\u662f\u65e0\u6bd2\u7684\u751f\u7269\u4f53\u3002\u5c3d\u7ba1\u5b83\u4eec\u5728\u5065\u5eb7\u7684\u75ab\u82d7\u63a5\u53d7\u8005\u8eab\u4e0a\u590d\u5236\uff0c\u4f46\u5b83\u4eec\u4e0d\u4f1a\u5bfc\u81f4\u75be\u75c5\u3002\u83b7\u5f97\u65e0\u6bd2\u751f\u7269\u4f53\u7684\u4e00\u79cd\u9014\u5f84\u6765\u81ea\u52a8\u7269\u4f53\u5185\u3002\u4f8b\u5982\uff0c\u5f15\u8d77\u725b\u75d8\u7684\u75c5\u6bd2\u5df2\u88ab\u975e\u5e38\u6210\u529f\u5730\u7528\u4f5c\u5929\u82b1\u75ab\u82d7(\u89c1BOX 25.1<\/span>)\u3002\u9488\u5bf9\u9ebb\u75b9\u548c\u816e\u817a\u708e\u7b49\u6d3b\u75ab\u82d7\u7684\u6297\u4f53\u5728\u63a5\u79cd\u75ab\u82d7\u540e\u4f1a\u6301\u7eed\u6570\u5341\u5e74\u3002\u5176\u4ed6\u6d3b\u75ab\u82d7\u6240\u4f7f\u7528\u7684\u4eba\u7c7b\u75c5\u539f\u4f53\u6d3b\u6027\u4e5f\u4f1a\u88ab\u51cf\u5f31\uff0c\u56e0\u6b64\u5b83\u4eec\u4e0d\u80fd\u81f4\u75c5\u3002\u4f20\u7edf\u4e0a\uff0c\u51cf\u6bd2\u6cd5\u662f\u901a\u8fc7\u5728\u4f53\u5916\u7279\u6b8a\u6761\u4ef6\u4e0b\u57f9\u517b\u751f\u7269\u4f53\u6765\u5b9e\u73b0\u7684\u3002\u5728\u672a\u6765\uff0c\u66f4\u591a\u7684\u6d3b\u75ab\u82d7\u53ef\u80fd\u4f1a\u901a\u8fc7\u76f4\u63a5\u64cd\u4f5c\u5b83\u4eec\u7684\u57fa\u56e0\u7ec4\u800c\u51cf\u6bd2\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u6d3b\u75ab\u82d7\u4e4b\u6240\u4ee5\u9ad8\u6548\uff0c\u6709\u4e09\u4e2a\u539f\u56e0(Fig 25.2<\/span>)\uff1a<\/p>\n

\u00b7<\/span><\/strong>\u5b83\u4eec\u8fdb\u884c\u590d\u5236\uff0c\u4ece\u800c\u80fd\u591f\u7a33\u5b9a\u63d0\u4f9b\u4e00\u5b9a\u6570\u91cf\u7684\u6297\u539f\u3002<\/p>\n

\u00b7<\/strong><\/span>\u5b83\u4eec\u5728\u7ec6\u80de\u5185\u590d\u5236\uff0c\u5c06\u6297\u539f\u80bd\u4f20\u9012\u7ed9MHC I\u7c7b\u5206\u5b50\uff0c\u4ece\u800c\u523a\u6fc0\u7ec6\u80de\u6bd2\u6027T\u6dcb\u5df4\u7ec6\u80de(CTL)\u3002<\/p>\n

\u00b7<\/span><\/strong>\u5b83\u4eec\u5728\u611f\u67d3\u7684\u89e3\u5256\u90e8\u4f4d\u590d\u5236\uff0c\u8fdb\u4e00\u6b65\u96c6\u4e2d\u514d\u75ab\u53cd\u5e94\u3002\u4f8b\u5982\uff0c\u7ecf\u9f3b\u6216\u7ecf\u53e3\u63a5\u79cd\u7684\u6d3b\u75ab\u82d7\u53ef\u6fc0\u53d1\u514d\u75ab\u7403\u86cb\u767dA(IgA)\u6297\u4f53\u3002<\/p>\n

\u6d3b\u75ab\u82d7\u4e5f\u53ef\u80fd\u88ab\u6392\u6cc4\u51fa\u6765\uff0c\u5e76\u4f20\u67d3\u7ed9\u5176\u4ed6\u672a\u63a5\u79cd\u75ab\u82d7\u7684\u4eba\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/section>\n<\/section>\n
\n
\n
\n


<\/p>\n<\/section>\n<\/section>\n

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Fig 25.2<\/span> \u810a\u9ad3\u7070\u8d28\u708e\u6216\u6d41\u611f\u7b49\u6d3b\u75ab\u82d7\u5728\u611f\u67d3\u90e8\u4f4d\u590d\u5236<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u5728\u4e24\u79cd\u60c5\u51b5\u4e0b\uff0c\u51cf\u6bd2\u6d3b\u75ab\u82d7\u53ef\u5bfc\u81f4\u4e25\u91cd\u611f\u67d3\u3002\u5728\u514d\u75ab\u7f3a\u9677\u60a3\u8005\u4e2d\uff0c\u5c3d\u7ba1\u5b83\u4eec\u5df2\u7ecf\u7ecf\u8fc7\u5927\u5e45\u5ea6\u51cf\u6bd2\uff0c\u4f46\u4ecd\u7136\u53ef\u4ee5\u5f15\u8d77\u4e25\u91cd\u611f\u67d3\u3002\u5076\u5c14\uff0c\u6d3b\u75ab\u82d7\u4e2d\u7684\u75c5\u6bd2\u4f1a\u81ea\u52a8\u8f6c\u56de\u4e3a\u6bd2\u6027\u5f88\u5f3a\u7684\u91ce\u751f\u578b\u3002\u810a\u9ad3\u7070\u8d28\u708e\u51cf\u6bd2\u75ab\u82d7\u4e0e\u91ce\u751f\u578b\u75c5\u6bd2\u53ea\u670910\u4e2a\u78b1\u57fa\u5bf9\u4e0d\u540c\u3002\u8fd9\u4e9b\u5fae\u5c0f\u7684\u5dee\u5f02\u4f7f\u5f97\u75c5\u6bd2\u5f88\u5bb9\u6613\u53d8\u5f02\u56de\u6bd2\u529b\u5f3a\u7684\u5f62\u5f0f\u3002\u7531\u4e8e\u5728\u4f9b\u6c34\u7cfb\u7edf\u4e2d\u53d1\u73b0\u4ece\u5f31\u6bd2\u5f62\u5f0f\u6062\u590d\u4e3a\u5f3a\u6bd2\u5f62\u5f0f\u7684\u810a\u9ad3\u7070\u8d28\u708e\u75c5\u6bd2\uff0c\u7f8e\u56fd\u518d\u6b21\u5f00\u59cb\u4f7f\u7528\u706d\u6d3b\u810a\u9ad3\u7070\u8d28\u708e\u75ab\u82d7\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
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\n

\u751f\u7269\u4f53\u4e5f\u53ef\u4ee5\u901a\u8fc7\u5de5\u7a0b\u624b\u6bb5\u6709\u610f\u5730\u53bb\u6539\u53d8\u57fa\u56e0\u3002\u4f8b\u5982\uff0c\u75c5\u6bd2\u8f7d\u4f53\u662f\u5df2\u7ecf\u5728\u4eba\u7c7b\u8eab\u4e0a\u5b89\u5168\u4f7f\u7528\u7684\u75c5\u6bd2\uff0c\u53ef\u4ee5\u4f5c\u4e3a\u8f7d\u4f53\u4ece\u53e6\u4e00\u79cd\u751f\u7269\u4e2d\u63d0\u53d6\u6240\u9700\u7684\u57fa\u56e0\u653e\u5728\u7ec6\u80de\u4e2d\u8868\u8fbe\u3002\u8fd9\u4e9b\u75ab\u82d7\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u662f\u5b9e\u9a8c\u6027\u7684\uff0c\u4f46\u5df2\u7ecf\u7528\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u3002\u4f8b\u5982\uff0c\u91d1\u4e1d\u96c0\u75d8\u75c5\u6bd2\u5df2\u88ab\u7528\u4f5cHIV\u57fa\u56e0\u7684\u8f7d\u4f53\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n

\u706d\u6d3b\u75ab\u82d7
<\/p>\n<\/section>\n

\n
\n
\n

\u5728\u6fc0\u53d1\u4fdd\u62a4\u6027\u514d\u75ab\u53cd\u5e94\u65b9\u9762\uff0c\u706d\u6d3b\u75ab\u82d7\u4e00\u822c\u4e0d\u50cf\u6d3b\u75ab\u82d7\u90a3\u6837<\/span>\u6709\u6548\uff0c\u5c3d\u7ba1\u7406\u8bba\u4e0a\u5b83\u4eec\u8981\u5b89\u5168\u5f97\u591a\u3002\u8fd9\u4e9b\u5dee\u5f02\u53ef\u5f52\u56e0\u4e8e\u706d\u6d3b\u75ab\u82d7\u4e0d\u80fd\u5728\u5bbf\u4e3b\u4e2d\u590d\u5236\uff0c\u4e5f\u4e0d\u80fd\u8fdb\u5165\u7ec6\u80de\u5185\u6297\u539f\u5448\u9012\u9014\u5f84\u3002\u6d41\u611f\u75ab\u82d7\u662f\u4ee5\u6d3b\u75c5\u6bd2\u7684\u5f62\u5f0f\u63d0\u4f9b\u7684\uff0c\u4f46\u66f4\u591a\u7684\u662f\u4ee5\u706d\u6d3b\u75c5\u6bd2\u7684\u5f62\u5f0f\u63d0\u4f9b\u3002\u8fd9\u4e9b\u5185\u5bb9\u5728BOX 25.2<\/span>\u4e2d\u8fdb\u884c\u4e86\u8ba8\u8bba\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n

\u4e9a\u5355\u4f4d\u75ab\u82d7<\/p>\n<\/section>\n

\n
\n
\n

\u4e9a\u5355\u4f4d\u662f\u75c5\u539f\u4f53\u7684\u7ec4\u6210\u90e8\u5206\uff0c\u4e3b\u8981\u8bf1\u5bfc\u6297\u4f53\u53cd\u5e94\u3002\u53ef\u4ee5\u901a\u8fc7\u7834\u574f\u6709\u6bd2\u751f\u7269\u4f53\u7ed3\u6784\uff0c\u63d0\u7eaf\u4e9a\u5355\u4f4d\uff0c\u7136\u540e\u4f7f\u5176\u5931\u6d3b\u800c\u4e0d\u4f1a\u81f4\u75c5\u6765\u5236\u5907\u4e9a\u5355\u4f4d\u75ab\u82d7\u3002\u5176\u4ed6\u79cd\u7c7b\u7684\u4e9a\u5355\u4f4d\u53ef\u4ee5\u7528\u91cd\u7ec4\u6280\u672f\u5236\u5907\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u4ece\u751f\u7269\u4f53\u4e2d\u63d0\u7eaf\uff0c\u7136\u540e\u706d\u6d3b\u7684\u4e9a\u5355\u4f4d\u88ab\u79f0\u4e3a\u7c7b\u6bd2\u7d20\u3002\u5b83\u4eec\u901a\u5e38\u662f\u7ec6\u83cc\u6bd2\u7d20\uff0c\u867d\u7136\u5b83\u4eec\u4fdd\u7559\u4e86\u6297\u539f\u6027\uff0c\u4f46\u7ecf\u8fc7\u5316\u5b66\u4fee\u9970\u4f7f\u5b83\u4eec\u53d8\u5f97\u5b89\u5168\uff0c\u4ea7\u751f\u7684\u4e2d\u548c\u6297\u4f53\u53ef\u4ee5\u963b\u65ad\u6bd2\u7d20\u7684\u4f5c\u7528\u3002\u767d\u5589\u548c\u7834\u4f24\u98ce\u7c7b\u6bd2\u7d20\u5c31\u662f\u901a\u8fc7\u8fd9\u79cd\u65b9\u6cd5\u5236\u5907\u75ab\u82d7\u7684\u5f88\u597d\u4f8b\u5b50\u3002\u4e0e\u5b8c\u6574\u7684\u751f\u7269\u4f53\u76f8\u6bd4\uff0c\u4e9a\u5355\u4f4d\u75ab\u82d7\u548c\u7c7b\u6bd2\u7d20\u75ab\u82d7\u7684\u514d\u75ab\u539f\u6027\u4e00\u822c\u8f83\u4f4e\uff0c\u5b83\u4eec\u53ef\u80fd\u9700\u8981\u4f50\u5242\u624d\u80fd\u6709\u6548\u53d1\u6325\u4f5c\u7528\u3002\u4e0e\u6d3b\u75ab\u82d7\u76f8\u6bd4\uff0c\u4e9a\u5355\u4f4d\u75ab\u82d7\u8bf1\u5bfc\u7684\u6297\u4f53\u5e94\u7b54\u6301\u7eed\u65f6\u95f4\u4e5f\u76f8\u5bf9\u8f83\u77ed\u3002\u4f8b\u5982\uff0c\u7834\u4f24\u98ce\u6297\u4f53\u5728\u63a5\u79cd\u75ab\u82d7\u540e\u53ea\u4f1a\u6301\u7eed10\u5e74\u5de6\u53f3\u3002\u8fd9\u5c31\u662f\u4e3a\u4ec0\u4e48\u8fd9\u79cd\u7c7b\u578b\u7684\u75ab\u82d7\u53ef\u80fd\u9700\u8981\u52a0\u5f3a\u5242\u7684\u539f\u56e0\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e59\u809d\u75ab\u82d7\u662f\u4f7f\u7528\u91cd\u7ec4\u6280\u672f\u751f\u4ea7\u7684\u4e00\u79cd\u4e9a\u5355\u4f4d\u6297\u539f(BOX 25.3<\/span>)\u3002\u4e59\u809d\u75ab\u82d7\u662f\u7531\u91cd\u7ec4\u75c5\u6bd2\u8868\u9762\u80bd\u7ec4\u6210\u7684\u75ab\u82d7\u3002\u9488\u5bf9\u8868\u9762\u80bd\u4ea7\u751f\u7684\u6297\u4f53\u5c06\u963b\u6b62\u75c5\u6bd2\u9644\u7740\u5728\u809d\u7ec6\u80de\u4e0a\u5e76\u8fdb\u5165\u809d\u7ec6\u80de\u3002\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u4e59\u809d\u75ab\u82d7\u5df2\u7ecf\u53d6\u5f97\u4e86\u5f88\u597d\u7684\u6548\u679c\u3002BOX 25.4<\/span>\u4e2d\u63cf\u8ff0\u4e86\u591a\u80bd\u75ab\u82d7\u53ef\u80fd\u4e0d\u4f1a\u6301\u7eed\u6709\u6548\u7684\u539f\u56e0\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u591a\u7cd6\u662f\u975e\u5e38\u5dee\u7684\u514d\u75ab\u539f\uff0c\u5f88\u5927\u7a0b\u5ea6\u4e0a\u662f\u56e0\u4e3a\u5b83\u4eec\u4f9d\u8d56\u4e8e\u975eT\u7ec6\u80de\u4f9d\u8d56\u6027B\u7ec6\u80de\u7684\u53cd\u5e94(\u7b2c14\u7ae0<\/span>\u548c\u7b2c16\u7ae0<\/span>)\uff0c\u4e0d\u80fd\u5236\u6210\u597d\u7684\u75ab\u82d7\u3002\u4e3a\u4e86\u514b\u670d\u8fd9\u4e00\u70b9\uff0c\u5229\u7528\u5316\u5b66\u624b\u6bb5\u5236\u6210\u4e86\u4e0e\u591a\u80bd\u6297\u539f\u5316\u5b66\u5076\u8054\u7684\u591a\u7cd6\uff0c\u7ecf\u5e38\u4f7f\u7528\u7684\u8026\u5408\u591a\u80bd\u4e3a\u7834\u4f24\u98ce\u7c7b\u6bd2\u7d20\u3002\u8fd9\u6837\u5bf9\u591a\u80bd\u6709\u53cd\u5e94\u7684T\u7ec6\u80de\u53ef\u4ee5\u4e3a\u5bf9\u591a\u7cd6\u6709\u53cd\u5e94\u7684B\u7ec6\u80de\u63d0\u4f9b\u5e2e\u52a9\u4ece\u800c\u4f7f\u75ab\u82d7\u66f4\u52a0\u6709\u6548(\u53c2\u89c1BOX 16.3<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
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\n

\u6700\u540e\u4e00\u79cd\u4e9a\u5355\u4f4d\u75ab\u82d7\u662fDNA\u75ab\u82d7\u3002\u5728\u8fd9\u79cd\u5b9e\u9a8c\u65b9\u6cd5\u4e2d\uff0c\u514d\u75ab\u539f\u6027\u86cb\u767d\u7684\u57fa\u56e0\u88ab\u5305\u88f9\u5728\u91d1\u5fae\u7403\u4e0a\uff0c\u5e76\u76f4\u63a5\u6ce8\u5c04\u5230\u7ec6\u80de(\u5982\u76ae\u80a4)\u4e2d\u3002\u5728\u5c0f\u9f20\u4e2d\uff0c\u8fd9\u5bfc\u81f4\u4e86\u6297\u4f53\u7684\u4ea7\u751f\uff0c\u8868\u660e\u8fd9\u4e9b\u57fa\u56e0\u5df2\u7ecf\u8f6c\u5f55(\u53e6\u89c1BOX 10.3<\/span>)\u3002\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u5728\u4eba\u7c7b\u8eab\u4e0a\uff0c\u8fd8\u4e0d\u53ef\u80fd\u63d0\u4f9b\u8db3\u591f\u7684DNA\u4f7f\u8fd9\u79cd\u65b9\u6cd5\u5e38\u89c4\u4f7f\u7528\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4f50\u5242<\/p>\n<\/section>\n

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\n
\n

\u4f50\u5242\u88ab\u5b9a\u4e49\u4e3a\u589e\u5f3a\u5bf9\u6297\u539f\u7684\u514d\u75ab\u53cd\u5e94(\u6297\u4f53\u6216T\u7ec6\u80de)\u7684\u7269\u8d28\u3002\u4f50\u5242\u63d0\u4f9b\u75c5\u539f\u4f53\u6216\u635f\u4f24\u76f8\u5173\u7684\u5206\u5b50\u6a21\u5f0f(PAMPs\u6216DAMP)\uff0c\u4ee5\u9a71\u52a8\u5148\u5929\u514d\u75ab\u7cfb\u7edf\u91ca\u653e\u5371\u9669\u4fe1\u53f7\uff0c\u4ece\u800c\u9a71\u52a8\u6297\u4f53\u548cT\u7ec6\u80de\u53cd\u5e94\u3002\u6d3b\u75ab\u82d7\u901a\u5e38\u4e0d\u9700\u8981\u4f50\u5242\uff0c\u56e0\u4e3a\u5b83\u4eec\u80fd\u591f\u63d0\u4f9b\u5371\u9669\u4fe1\u53f7\u5e76\u523a\u6fc0Toll\u6837\u53d7\u4f53(TLR)\u672c\u8eab\u3002\u4f8b\u5982\uff0c\u5361\u4ecb\u82d7(BCG)\u662f\u4e00\u79cd\u7ed3\u6838\u75c5\u6d3b\u75ab\u82d7\uff0c\u4f1a\u4ea7\u751f\u5927\u91cf\u7684\u7ec6\u83cc\u7cd6\u6765\u6fc0\u6d3bTLR2\u548c4\u3002\u706d\u6d3b\u7684\u5168\u75ab\u82d7\u4e5f\u542b\u6709\u6fc0\u6d3bTLR\u7684\u7269\u8d28\uff0c\u53ef\u4ee5\u4f5c\u4e3a\u4f50\u5242\u3002\u4f7f\u7528\u91cd\u7ec4\u6216\u7eaf\u5316\u86cb\u767d\u5236\u5907\u7684\u75ab\u82d7\u4e2d\u5929\u7136\u4f50\u5242\u542b\u91cf\u4e0d\u8db3\uff0c\u56e0\u6b64\u5fc5\u987b\u6dfb\u52a0\u5408\u6210\u4f50\u5242\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u76f4\u523021\u4e16\u7eaa\uff0c\u6c22\u6c27\u5316\u94dd(\u660e\u77fe)\u8fd8\u662f\u4eba\u7c7b\u552f\u4e00\u5e38\u89c4\u4f7f\u7528\u7684\u5408\u6210\u4f50\u5242\uff0c\u5b83\u589e\u5f3a\u5404\u79cd\u4e9a\u5355\u4f4d\u75ab\u82d7\u7684\u6548\u679c\u3002\u660e\u77fe\u662f\u4f5c\u4e3a\u75ab\u82d7\u7684\u4f50\u5242\u5f15\u5165\u7684\uff0c\u5728\u5f15\u5165\u65f6\u8fd8\u4e0d\u77e5\u9053\u5b83\u662f\u5982\u4f55\u8d77\u4f5c\u7528\u7684\u3002\u660e\u77fe\u6fc0\u6d3b\u5de8\u566c\u7ec6\u80de\uff0c\u7136\u540e\u5de8\u566c\u7ec6\u80de\u5206\u6ccc\u708e\u6027\u7ec6\u80de\u56e0\u5b50\uff0c\u5e76\u5c06\u6297\u539f\u5448\u9012\u7ed9T\u3001B\u7ec6\u80de\u3002\u660e\u77fe\u53ef\u80fd\u662f\u901a\u8fc7\u9020\u6210\u5c40\u90e8\u7ec4\u7ec7\u635f\u4f24\uff0c\u7136\u540e\u6fc0\u6d3b\u5de8\u566c\u7ec6\u80de\u4e0a\u7684DAMPs\u6765\u505a\u5230\u8fd9\u4e00\u70b9\u7684\u3002\u660e\u77fe\u4e0d\u662f\u4e00\u79cd\u5f3a\u6709\u529b\u7684\u4f50\u5242\uff0c\u76ee\u524d\u4ecd\u5728\u7ee7\u7eed\u5bfb\u627e\u6539\u8fdb\u75ab\u82d7\u7684\u65b9\u6cd5\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u6700\u8fd1\uff0c\u4ece\u6c99\u95e8\u6c0f\u83cc\u591a\u7cd6\u4e2d\u63d0\u53d6\u7684\u5355\u78f7\u9170\u8102(MPL)\u88ab\u53d1\u73b0\u662f\u4e00\u79cd\u6709\u6548\u7684TLR-4\u6fc0\u52a8\u5242\u3002\u5de8\u566c\u7ec6\u80de\u66b4\u9732\u4e8eMPL\u540e\uff0c\u767d\u7ec6\u80de\u4ecb\u7d2012(IL-12)\u5206\u6ccc\u589e\u52a0\uff0cMHC II\u7c7b\u5206\u5b50\u8868\u8fbe\u4e0a\u8c03\u3002\u4ece\u7406\u8bba\u4e0a\u8bb2\uff0c\u8fd9\u4e9b\u4f5c\u7528\u589e\u52a0\u4e86\u6297\u539f\u63d0\u5448\uff0c\u5e76\u4f7f\u514d\u75ab\u53cd\u5e94\u504f\u5411\u8f85\u52a9\u6027T\u7ec6\u80de1(TH1)\u578b\u53cd\u5e94\u3002MPL\u76ee\u524d\u4f5c\u4e3a\u9700\u8981\u91cd\u8981\u7684\u8bb8\u53ef\u75ab\u82d7\u7684\u4f50\u5242\u4f7f\u7528\uff0c\u4f8b\u5982\u5bf9\u6297\u4eba\u4e73\u5934\u7624\u75c5\u6bd2(HPV)\u548c\u759f\u75be(\u89c1BOX 25.4<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n

\u8fdb\u5165\u7ec6\u80de\u5185\u9014\u5f84<\/p>\n<\/section>\n

\n
\n
\n

\u4e9a\u5355\u4f4d\u75ab\u82d7\u7684\u7b2c\u4e8c\u4e2a\u95ee\u9898\u662f\uff0c\u5b83\u4eec\u4e0d\u4f1a\u8fdb\u5165\u7ec6\u80de\u5185\u6297\u539f\u5904\u7406\u9014\u5f84\uff0c\u56e0\u6b64\u4e0d\u4f1a\u5f15\u53d1CTL\u53cd\u5e94\uff0c\u800cCTL\u53cd\u5e94\u5728\u5e94\u5bf9HIV\u7b49\u7ec6\u80de\u5185\u611f\u67d3\u65b9\u9762\u5c24\u4e3a\u91cd\u8981\u3002\u6765\u81ea\u7ec6\u80de\u5185\u75c5\u539f\u4f53(\u5982\u810a\u9ad3\u7070\u8d28\u708e\u75c5\u6bd2\u548c\u5361\u4ecb\u82d7)\u7684\u6d3b\u75ab\u82d7\u80fd\u591f\u8fdb\u5165\u7ec6\u80de\u5185\u9014\u5f84\u3002\u6709\u4e00\u4e9b\u65b0\u6280\u672f\u6709\u52a9\u4e8e\u8fdb\u5165\u7ec6\u80de\u5185\u9014\u5f84\uff1a<\/p>\n

\u00b7<\/strong><\/span>\u514d\u75ab\u523a\u6fc0\u590d\u5408\u7269(ISCOM)\u662f\u8102\u7c7b\u548c\u4e9a\u5355\u4f4d\u6297\u539f\u7684\u80f6\u675f\uff0c\u5177\u6709\u4eb2\u8102\u6027\uff0c\u53ef\u4ee5\u7a7f\u900f\u7ec6\u80de\u819c(Fig 25.3<\/span>)\u3002\u8fd9\u4e9b\u75ab\u82d7\u53ef\u80fd\u4f1a\u52a0\u5165\u75c5\u6bd2\u6837\u9897\u7c92(VLP)\uff0c\u4ece\u800c\u8fdb\u4e00\u6b65\u7684\u589e\u52a0\u7ed3\u6784\u3002\u8102\u8d28\u548cVLP\u5df2\u7528\u4e8e\u759f\u75be\u75ab\u82d7(\u89c1BOX 25.4<\/span>)\u3002<\/p>\n

\u00b7<\/strong>\u8f7d\u4f53<\/span><\/span>\u662f\u901a\u8fc7\u57fa\u56e0\u6539\u9020\u800c\u53d8\u5f97\u5b89\u5168\u7684\u6d3b\u75c5\u6bd2\uff0c\u4f8b\u5982\u91d1\u4e1d\u96c0\u75d8\u3002\u53ef\u4ee5\u6dfb\u52a0\u75c5\u539f\u4f53\u7684\u57fa\u56e0\uff0c\u4f8b\u5982HIV\u3002\u8fd9\u4e9b\u57fa\u56e0\u5728\u7ec6\u80de\u5185\u8868\u8fbe\uff0c\u4f46\u6ca1\u6709\u6d3b\u4f53\u75c5\u539f\u4f53(HIV)\u7684\u590d\u5236\u3002<\/p>\n

\u00b7<\/span>\u5982\u4e0a\u6240\u8ff0\u7684DNA\u75ab\u82d7\u53ef\u4ee5\u4f5c\u4e3a\u7ec6\u80de\u5185\u8868\u8fbe\u86cb\u767d\u8d28\u7684\u4e00\u79cd\u65b9\u5f0f\uff0c\u5982\u679c\u53ef\u4ee5\u6ce8\u5c04\u8db3\u591f\u7684DNA\u7684\u8bdd\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

Table 25.2<\/span>\u603b\u7ed3\u4e86\u672c\u7ae0\u4e2d\u63d0\u5230\u7684\u4e00\u4e9b\u5b9e\u9a8c\u6027\u75ab\u82d7\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
<\/section>\n<\/section>\n
\n
\n
\n


<\/p>\n<\/section>\n<\/section>\n

\n
\n

Table 25.2<\/span> \u5982\u4f55\u63d0\u9ad8\u75ab\u82d7\u6709\u6548\u6027<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
<\/section>\n<\/section>\n
\n
\n
\n


<\/p>\n<\/section>\n<\/section>\n

\n
\n

Fig 25.3<\/span> \u53ef\u80fd\u63d0\u4f9b\u5b89\u5168\u75ab\u82d7\u4ee5\u6fc0\u53d1\u7ec6\u80de\u6bd2\u6027T\u6dcb\u5df4\u7ec6\u80de\u53cd\u5e94\u7684\u6280\u672f<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n


<\/p>\n<\/section>\n<\/section>\n

\n
\n

\u75ab\u82d7\u63a5\u79cd\u65f6\u95f4\u8868<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u75ab\u82d7\u63a5\u79cd\u65f6\u95f4\u8868\u8003\u8651\u4e86\u6bcf\u79cd\u7c7b\u578b\u611f\u67d3\u7684\u4e34\u5e8a\u5f71\u54cd\u3002\u4f8b\u5982\uff0c\u98ce\u75b9\u75ab\u82d7\u7684\u4e3b\u8981\u76ee\u7684\u662f\u9884\u9632\u5bab\u5185\u611f\u67d3\uff0c\u5bab\u5185\u611f\u67d3\u53ef\u80fd\u5bfc\u81f4\u7578\u5f62\uff0c\u6240\u4ee5\u5728\u9752\u6625\u671f\u4e4b\u524d\u63a5\u79cd\u6ca1\u6709\u4ec0\u4e48\u610f\u4e49\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u4fdd\u62a4\u975e\u5e38\u5e74\u5e7c\u7684\u5a74\u513f\u514d\u53d7\u55dc\u8840\u6746\u83cc\u7684\u4fb5\u5bb3\u662f\u53ef\u884c\u7684\uff0c\u56e0\u4e3a\u8fd9\u79cd\u5fae\u751f\u7269\u5728\u8fd9\u4e2a\u5e74\u9f84\u6bb5\u9020\u6210\u7684\u635f\u5bb3\u4f24\u6700\u5927(\u89c1<\/span>BOX 16.3<\/span>)\u3002\u7136\u800c\uff0c\u5373\u4f7f\u4f5c\u4e3a\u7ed3\u5408\u75ab\u82d7\uff0c\u591a\u7cd6\u4e5f\u4e0d\u80fd\u5728\u65b0\u751f\u513f\u4e2d\u5f15\u53d1\u6297\u4f53\u3002\u4eba\u7c7b\u4e73\u5934\u7624\u75c5\u6bd2(HPV)\u75ab\u82d7\u7684\u76ee\u7684\u662f\u9632\u6b62\u5bfc\u81f4\u5bab\u9888\u764c\u7684HPV\u6bd2\u682a\u7684\u6027\u4f20\u64ad\u3002\u51fa\u4e8e\u8fd9\u4e2a\u539f\u56e0\uff0c\u8fd9\u4e9b\u75ab\u82d7\u662f\u5728\u9752\u6625\u671f\u65f6\u63a5\u79cd\u7684\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u4e16\u754c\u4e0d\u540c\u5730\u533a\u7684\u75ab\u82d7\u65f6\u95f4\u8868\u4e5f\u5404\u4e0d\u76f8\u540c(Table 25.3<\/span>)\u3002\u4f8b\u5982\uff0c\u9ebb\u75b9\u662f\u53d1\u5c55\u4e2d\u56fd\u5bb6\u5a74\u513f\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u56e0\u6b64\u5e94\u5c3d\u65e9\u63a5\u79cd\u75ab\u82d7\u3002\u5728\u53d1\u8fbe\u56fd\u5bb6\uff0c\u9ebb\u75b9\u5df2\u7ecf\u53d8\u5f97\u7f55\u89c1\uff0c\u800c\u4e14\u5f80\u5f80\u5f71\u54cd\u7684\u662f\u5b66\u9f84\u513f\u7ae5\uff0c\u56e0\u6b64\u75ab\u82d7\u53ef\u4ee5\u7a0d\u7a0d\u665a\u4e00\u70b9\u63a5\u79cd\u3002\u7136\u800c\uff0c\u5f71\u54cd\u53d1\u5c55\u4e2d\u56fd\u5bb6\u75ab\u82d7\u4f7f\u7528\u7684\u4e3b\u8981\u539f\u56e0\u662f\u6210\u672c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
<\/section>\n<\/section>\n
\n
\n
\n


<\/p>\n<\/section>\n<\/section>\n

\n
\n

Fig 25.3<\/span> \u53d1\u8fbe\u56fd\u5bb6\u548c\u53d1\u5c55\u4e2d\u56fd\u5bb6\u7684\u75ab\u82d7\u63a5\u79cd\u65f6\u8868<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\n

BOX 25.1<\/span>\u5929\u82b1\u75ab\u82d7<\/span><\/p>\n<\/section>\n<\/section>\n

\n
\n
<\/svg><\/section>\n<\/section>\n
\n
<\/svg><\/section>\n<\/section>\n<\/section>\n
\n
\n

\u4e00\u540d32\u5c81\u7684\u58eb\u5175\u88ab\u8981\u6c42\u63a5\u79cd\u5929\u82b1\u75ab\u82d7\u3002\u4f60\u5bf9\u8fd9\u79cd\u75ab\u82d7\u4e86\u89e3\u591a\u5c11\uff1f\u4e3a\u4ec0\u4e48\u8981\u7ed9\u8fd9\u4e2a\u4eba\u63a5\u79cd\u5462\uff1f<\/p>\n

\u5929\u82b1(\u5929\u82b1\u75c5\u6bd2)\u662f\u4e00\u79cd\u5177\u6709\u9ad8\u5ea6\u4f20\u67d3\u6027\u7684\u75c5\u6bd2\u611f\u67d3\uff0c\u4f1a\u5f15\u8d77\u8d77\u6ce1\u7684\u76ae\u80a4\u53cd\u5e94\uff0c\u6b7b\u4ea1\u7387\u4e3a10%\u81f330%\uff0c\u76f8\u5173\u7684\u725b\u75d8\u4f1a\u5f15\u8d77\u6e29\u548c\u7684\u5c40\u90e8\u8d77\u6ce1\u53cd\u5e94\u3002\u8bb8\u591a\u4e16\u7eaa\u4ee5\u524d\uff0c\u4eba\u4eec\u5c31\u77e5\u9053\u725b\u75d8\u611f\u67d3\u53ef\u4ee5\u9884\u9632\u968f\u540e\u7684\u5929\u82b1\u611f\u67d3\uff0c\u4f46\u76f4\u523018\u4e16\u7eaa\u672b\u7231\u5fb7\u534e\u00b7\u8a79\u7eb3\u624d\u6b63\u5f0f\u8bc1\u660e\uff0c\u6709\u610f\u63a5\u79cd\u725b\u75d8\u75c5\u6bd2\u53ef\u4ee5\u9884\u9632\u5929\u82b1\uff0c\u8fd9\u5c31\u662f\u201c\u75ab\u82d7\u63a5\u79cd\u201d\u4e00\u8bcd\u7684\u7531\u6765\u3002<\/p>\n

\u5168\u7403\u5929\u82b1\u75ab\u82d7\u63a5\u79cd\u662f\u7531\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u8fdb\u884c\u7684\uff0c\u4e0a\u4e00\u6b21\u666e\u901a\u4eba\u7fa4\u4e2d\u7684\u5929\u82b1\u75c5\u4f8b\u53d1\u751f\u57281977\u5e74\u3002\u4ece\u90a3\u65f6\u8d77\uff0c\u552f\u4e00\u62a5\u544a\u7684\u5929\u82b1\u75c5\u4f8b\u53d1\u751f\u5728\u5b9e\u9a8c\u5ba4\u5de5\u4f5c\u4eba\u5458\u8eab\u4e0a\u3002\u4e00\u4e9b\u4f9b\u5e94\u5b9e\u9a8c\u7528\u7684\u5929\u82b1\u75c5\u6bd2\u88ab\u4fdd\u7559\u5728\u4e16\u754c\u5404\u5730\u7684\u5b9e\u9a8c\u5ba4\uff0c\u4eba\u4eec\u62c5\u5fc3\u8fd9\u4e9b\u4f9b\u5e94\u7684\u91ce\u751f\u5929\u82b1\u75c5\u6bd2\u53ef\u80fd\u88ab\u751f\u7269\u6050\u6016\u5206\u5b50\u83b7\u53d6\u3002\u7531\u4e8e\u5168\u7403\u75ab\u82d7\u63a5\u79cd\u572880\u5e74\u4ee3\u521d\u505c\u6b62\uff0c\u5927\u591a\u6570\u5e74\u8f7b\u4eba\u5bf9\u5929\u82b1\u6ca1\u6709\u514d\u75ab\u529b\uff0c\u56e0\u6b64\uff0c\u8fd9\u79cd\u75c5\u6bd2\u53ef\u4ee5\u88ab\u7528\u4f5c\u751f\u7269\u6b66\u5668\u3002\u4e00\u4e9b\u653f\u5e9c\u91cd\u65b0\u5f00\u59cb\u63a5\u79cd\u5929\u82b1\u75ab\u82d7\uff0c\u81f3\u5c11\u662f\u4e3a\u519b\u4e8b\u4eba\u5458\u63a5\u79cd\u5929\u82b1\u75ab\u82d7\u3002<\/p>\n

\u75d8\u82d7\u662f\u4e00\u79cd\u88ab\u522e\u5165\u76ae\u80a4\u8868\u9762\u7684\u6d3b\u75ab\u82d7\u3002\u5b83\u5728\u76ae\u80a4\u4e2d\u590d\u5236\uff0c\u5e76\u5f15\u8d77\u76f8\u5f53\u5927\u7684\u5c40\u90e8\u708e\u75c7\u3002\u5728\u63a5\u79cd\u75ab\u82d7\u540e\u7684\u7b2c\u4e00\u5468\uff0c\u6c34\u6ce1\u4f1a\u5f62\u6210\uff0c\u5e76\u5728\u7b2c\u4e8c\u5468\u9010\u6e10\u6108\u5408\u3002\u6c34\u75b1\u542b\u6709\u6d3b\u7684\u75d8\u82d7\u75c5\u6bd2\uff0c\u6c34\u75b1\u6db2\u53ef\u4ee5\u611f\u67d3\u5176\u4ed6\u4eba\u3002\u5728\u514d\u75ab\u7cfb\u7edf\u6709\u7f3a\u9677\u7684\u60a3\u8005\u4e2d\uff0c\u63a5\u79cd\u5929\u82b1\u75ab\u82d7\u4f1a\u5bfc\u81f4\u75d8\u82d7\u75c5\u6bd2\u7684\u5e7f\u6cdb\u4f20\u64ad\u3001\u5168\u8eab\u76ae\u75b9\u548c\u4e25\u91cd\u75be\u75c5\u7684\u98ce\u9669\u3002<\/p>\n

\u7531\u4e8e\u75d8\u82d7\u75c5\u6bd2\u5728\u76ae\u80a4\u7684\u7ec6\u80de\u5185\u590d\u5236\uff0c\u5b83\u5411\u7ec6\u80de\u5185\u7684\u6297\u539f\u5448\u9012\u9014\u5f84\u8f93\u9001\u9ad8\u6c34\u5e73\u7684\u6297\u539f\uff0c\u5e76\u523a\u6fc0\u7ec6\u80de\u6bd2\u6027T\u6dcb\u5df4\u7ec6\u80de(CTL)\u7684\u53d1\u5c55\u3002\u53d1\u82bd\u8fdb\u5165\u7ec6\u80de\u5916\u7a7a\u95f4\u7684\u75c5\u6bd2\u5c06\u88ab\u541e\u566c\uff0c\u8fdb\u5165\u7ec6\u80de\u5916\u6297\u539f\u9014\u5f84\uff0c\u5e76\u523a\u6fc0\u8f85\u52a9\u6027T\u7ec6\u80de\u548c\u6297\u4f53\u7684\u4ea7\u751f\u3002\u5728\u5168\u7403\u75ab\u82d7\u63a5\u79cd\u8ba1\u5212\u91cc\uff0c\u5df2\u7ecf\u5efa\u7acb\u4e86\u5927\u91cf\u5173\u4e8e\u6297\u4f53\u548cCTL\u53cd\u5e94\u7684\u5bff\u547d\u7684\u6570\u636e\u3002\u56e0\u4e3a\u6bcf\u4e2a\u4eba\u53ea\u63a5\u79cd\u4e86\u4e00\u6b21\u75ab\u82d7\uff0c\u800c\u4e14\u81ea\u7136\u725b\u75d8\u611f\u67d3\u4e0d\u662f\u5730\u65b9\u6027\u7684\uff0c\u6240\u4ee5\u53ef\u4ee5\u51c6\u786e\u5730\u5b9a\u4f4d\u4e3a\u725b\u75d8\u75ab\u82d7\u63a5\u79cd\u3002\u73af\u5883\u75ab\u82d7\u7684\u7f3a\u4e4f\u786e\u4fdd\u4e86\u6d4b\u91cf\u5230\u7684\u4efb\u4f55\u53cd\u5e94\u90fd\u4e0d\u4f1a\u56e0\u4e3a\u518d\u6b21\u63a5\u89e6\u8fd9\u79cd\u6216\u4efb\u4f55\u4ea4\u53c9\u53cd\u5e94\u7684\u6709\u673a\u4f53\u800c\u53d7\u5230\u5f71\u54cd\u3002<\/p>\n

Fig 25.4<\/span>\u663e\u793a\u4e86\u5bf9\u75d8\u82d7\u75c5\u6bd2\u7684\u514d\u75ab\u53cd\u5e94\u7684\u5bff\u547d\uff0c\u4ee5\u53ca\u514d\u53d7\u611f\u67d3\u7684\u4fdd\u62a4\u6c34\u5e73\u3002\u6570\u636e\u663e\u793a\uff0c\u6297\u4f53\u6c34\u5e73\u81f3\u5c11\u53ef\u4ee5\u7ef4\u630160\u5e74\u3002\u75d8\u82d7\u7279\u5f02\u6027B\u548cT\u7ec6\u80de\u7684\u6570\u91cf\u5728\u63a5\u79cd\u75ab\u82d7\u540e\u7684\u51e0\u5e74\u5185\u7acb\u5373\u4e0b\u964d\uff0c\u4f46\u968f\u540e\u4fdd\u6301\u4e0d\u53d8\u3002\u5373\u4f7f\u5728\u63a5\u79cd\u75ab\u82d750\u5e74\u540e\uff0c\u75d8\u82d7\u7279\u5f02\u6027B\u7ec6\u80de\u4ecd\u5360\u6240\u6709\u5faa\u73afB\u7ec6\u80de\u76841\/1000\u3002\u8fd9\u4e9bT\u548cB\u7ec6\u80de\u662f\u6709\u529f\u80fd\u7684\uff1b\u5982\u679c\u91cd\u65b0\u63a5\u79cd\u75ab\u82d7\uff0c\u5b83\u5c06\u542f\u52a8\u7b2c\u4e8c\u6b21\u514d\u75ab\u53cd\u5e94\uff0c\u8fd9\u8868\u660e\u5b58\u5728\u529f\u80fd\u8bb0\u5fc6T\u548cB\u7ec6\u80de\u3002\u5c3d\u7ba1T\u7ec6\u80de\u53cd\u5e94\u4e0b\u964d\uff0c\u534a\u8870\u671f\u4e3a8\u523010\u5e74\uff0c\u4f46\u6297\u4f53\u6c34\u5e73\u548c\u5bf9\u611f\u67d3\u7684\u4fdd\u62a4\u5728\u63a5\u79cd\u75ab\u82d7\u540e\u81f3\u5c11\u6301\u7eed60\u5e74\u3002<\/p>\n<\/section>\n<\/section>\n

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Fig 25.4<\/span> \u6297\u4f53\u5bff\u547d\u4e0eB\u7ec6\u80de\u548cT\u7ec6\u80de\u5bf9\u5929\u82b1\u53cd\u5e94\u7684\u5173\u7cfb\u3002\u7ea2\u7ebf\u4ee3\u8868\u6297\u4f53\u6c34\u5e73\uff0c\u7eff\u7ebf\u4ee3\u8868B\u7ec6\u80de\u6570\u91cf\uff0c\u84dd\u7ebf\u4ee3\u8868T\u7ec6\u80de\u53cd\u5e94\u6c34\u5e73\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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BOX 25.2<\/span>\u6d41\u611f\u75ab\u82d7<\/span><\/p>\n<\/section>\n<\/section>\n

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<\/svg><\/section>\n<\/section>\n
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<\/svg><\/section>\n<\/section>\n<\/section>\n
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\u6d41\u611f\u662f\u4e00\u79cd\u547c\u5438\u9053\u75c5\u6bd2\uff0c\u4f1a\u5728\u5e7c\u513f\u548c\u8001\u5e74\u4eba\u4e2d\u5f15\u8d77\u4e25\u91cd\u611f\u67d3\u3002\u6bcf\u5e74\uff0c\u572810\u6708\u5230\u6b21\u5e742\u6708\u7684\u6d41\u611f\u5b63\u8282\uff0c\u6d41\u611f\u5728\u7f8e\u56fd\u9020\u6210\u5927\u7ea63.6\u4e07\u4eba\u6b7b\u4ea1\u30021918\u5e74\uff0c\u7b2c\u4e00\u6b21\u4e16\u754c\u5927\u6218\u521a\u521a\u7ed3\u675f\uff0c\u4e00\u79cd\u65b0\u7684\u6d41\u611f\u75c5\u6bd2\u51fa\u73b0\uff0c\u5e76\u5f15\u53d1\u4e86\u4e00\u573a\u6d41\u611f\u5927\u6d41\u884c\u3002\u201c\u897f\u73ed\u7259\u6d41\u611f\u201d\u57289\u4e2a\u6708\u5185\u5e2d\u5377\u5168\u7403\uff0c\u9020\u62104,000\u4e07\u4eba\u6b7b\u4ea1\u3002<\/span><\/p>\n

\u6d41\u611f\u662f\u4e00\u79cdRNA\u75c5\u6bd2\uff0c\u5b83\u4f7f\u7528\u4e00\u79cd\u540d\u4e3a\u8840\u51dd\u7d20\u7684\u86cb\u767d\u8d28\u5c06\u7cd6\u7ed3\u5408\u5728\u547c\u5438\u9053\u4e0a\u76ae\u7ec6\u80de\u4e0a\u3002\u6d41\u611f\u662f\u4e00\u79cd\u7ec6\u80de\u75c5\u53d8\uff0c\u5b83\u4f1a\u5bf9\u5176\u611f\u67d3\u7684\u7ec6\u80de\u9020\u6210\u635f\u5bb3\u3002\u53cc\u94fe\u6838\u7cd6\u6838\u9178\u7684\u5b58\u5728\u523a\u6fc0\u547c\u5438\u9053\u7ec6\u80de\u5728\u75c5\u6bd2\u611f\u67d3\u540e\u51e0\u5c0f\u65f6\u5185\u5206\u6ccc\u5e72\u6270\u7d20-\u03b1\uff0c\u4ece\u800c\u6291\u5236\u75c5\u6bd2\u590d\u5236(\u7b2c20\u7ae0<\/span>)\uff0c\u5e76\u51cf\u7f13\u6d41\u611f\u5728\u80ba\u90e8\u7684\u4f20\u64ad\u3002<\/p>\n

\u6811\u7a81\u72b6\u7ec6\u80de\u8fc1\u79fb\u5230\u5c40\u90e8\u6dcb\u5df4\u7ed3\uff0c\u5e76\u5c06\u6297\u539f\u9012\u5448\u7ed9T\u7ec6\u80de\u3002\u5728\u8f85\u52a9\u6027T\u7ec6\u80de1\u578b(TH1)\u7684\u4f5c\u7528\u4e0b\uff0c\u7ec6\u80de\u6bd2\u6027T\u6dcb\u5df4\u7ec6\u80de(CTL)\u57282~3\u5929\u540e\u5f00\u59cb\u51fa\u73b0\u3002\u8fd9\u4e9b\u7ec6\u80de\u6e05\u9664\u6b8b\u7559\u7684\u611f\u67d3\u7ec6\u80de\uff0c\u4ece\u800c\u5b9e\u73b0\u706d\u83cc\u514d\u75ab\u3002<\/p>\n

\u6d41\u611f\u4e5f\u4f1a\u5f15\u8d77\u6297\u4f53\u53cd\u5e94\uff0c\u514d\u75ab\u7403\u86cb\u767dM(IgM)\u6297\u4f53\u5728\u5927\u7ea65\u5929\u540e\u5f00\u59cb\u51fa\u73b0\u3002\u8fd9\u4e9b\u4e2d\u548c\u6297\u4f53\u4e0e\u8840\u51dd\u7d20\u7ed3\u5408\uff0c\u9632\u6b62\u75c5\u6bd2\u611f\u67d3\u7ec6\u80de\u3002\u5bf9\u6d41\u611f\u7684\u6297\u4f53\u53cd\u5e94\u53d1\u5c55\u5f97\u592a\u665a\uff0c\u65e0\u6cd5\u5728\u6e05\u9664\u5df2\u786e\u5b9a\u7684\u611f\u67d3\u65b9\u9762\u53d1\u6325\u4e3b\u8981\u4f5c\u7528\uff0c\u4f46\u5728\u9632\u6b62\u518d\u6b21\u611f\u67d3\u76f8\u540c\u7684\u75c5\u6bd2\u682a\u65b9\u9762\u975e\u5e38\u91cd\u8981\u3002<\/p>\n

\u6d41\u611f\u662f\u4e00\u79cd\u76f8\u5bf9\u4e0d\u7a33\u5b9a\u7684RNA\u75c5\u6bd2\uff0c\u53ef\u4ee5\u53d1\u751f\u81ea\u53d1\u53d8\u5f02\u3002\u6e10\u8fdb\u5f0f\u7a81\u53d8\u4f1a\u6162\u6162\u6539\u53d8\u75c5\u6bd2\u57fa\u56e0\u7ec4\uff0c\u5bfc\u81f4\u6297\u539f\u6f02\u79fb\u3002\u7531\u4e8e\u53d8\u5f02\u75c5\u6bd2\u4e0e\u73b0\u6709\u6bd2\u682a\u5728\u6297\u539f\u4e0a\u6709\u4e00\u4e9b\u76f8\u4f3c\u4e4b\u5904\uff0c\u73b0\u6709\u514d\u75ab\u5177\u6709\u90e8\u5206\u4fdd\u62a4\u6027\uff0c\u8fd9\u610f\u5473\u7740\u4e0d\u4f1a\u53d1\u751f\u5927\u8303\u56f4\u6d41\u884c\uff0c\u611f\u67d3\u901a\u5e38\u662f\u6e29\u548c\u7684(Fig 25.5<\/span>)\u3002\u66f4\u5feb\u901f\u3001\u66f4\u5e7f\u6cdb\u7684\u57fa\u56e0\u53d8\u5316\u4e5f\u53ef\u80fd\u53d1\u751f\u3002\u5f53\u5bbf\u4e3b\u52a8\u7269\u611f\u67d3\u4e86\u4e24\u79cd\u4e0d\u540c\u7684\u6d41\u611f\u75c5\u6bd2\u682a\u65f6\uff0c\u8fd9\u79cd\u4e8b\u4ef6\u5c31\u4f1a\u53d1\u751f\uff0c\u8fd9\u4e24\u4e2a\u6bd2\u682a\u4ea4\u6362\u4e86\u57fa\u56e0\u7247\u6bb5\uff0c\u7b2c\u4e09\u4e2a\u6bd2\u682a\u5c31\u4ea7\u751f\u4e86\uff0c\u8fd9\u88ab\u79f0\u4e3a\u57fa\u56e0\u8f6c\u79fb\uff0c\u53ef\u80fd\u4f1a\u5bfc\u81f4\u6bcf\u9694\u51e0\u5e74\u53d1\u751f\u4e00\u6b21\u7684\u6d41\u611f\u5927\u6d41\u884c\u3002\u8fd9\u4e9b\u9057\u4f20\u4e8b\u4ef6\u5927\u591a\u53d1\u751f\u5728\u4eba\u7c7b\u548c\u9e1f\u7c7b\u4e4b\u95f4\uff0c\u5df2\u7ecf\u6709\u4e00\u4e9b\u4eba\u611f\u67d3\u4e86\u65b0\u7684\u79bd\u6d41\u611f\u75c5\u6bd2\uff0c\u4f46\u5728\u64b0\u5199\u672c\u6587\u65f6\uff0c\u8fd8\u6ca1\u6709\u8bc1\u636e\u8868\u660e\u5df2\u7ecf\u53c8\u51fa\u73b0\u4e86\u4e00\u79cd\u65b0\u7684\u3001\u53d8\u5f02\u7684\u6d41\u611f\u75c5\u6bd2\u3002\u5982\u679c\u771f\u7684\u51fa\u73b0\u4e00\u79cd\u80fd\u591f\u5728\u4eba\u4e0e\u4eba\u4e4b\u95f4\u4f20\u64ad\u7684\u65b0\u7684\u3001\u8f6c\u79fb\u7684\u75c5\u6bd2\uff0c\u7531\u4e8e\u5927\u89c4\u6a21\u7684\u822a\u7a7a\u65c5\u884c\uff0c\u5168\u7403\u611f\u67d3\u5f88\u53ef\u80fd\u5728\u51e0\u5468\u5185\u5c31\u4f1a\u51fa\u73b0\u3002<\/p>\n<\/section>\n<\/section>\n

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<\/section>\n<\/section>\n
\n

Fig 25.5 \u7531\u4e8e<\/span><\/span>\u5355\u78b1\u57fa\u5bf9\u7a81\u53d8\u5bfc\u81f4\u7684\u6f02\u79fb\u76f8\u5bf9\u9891\u7e41\u3002\u8f6c\u53d8\u53d1\u751f\u7684\u9891\u7387\u8981\u4f4e\u5f97\u591a\uff0c\u5f53\u4eba\u7c7b\u6d41\u611f\u75c5\u6bd2\u4e0e\u52a8\u7269\u75c5\u6bd2\u4ea4\u6362\u57fa\u56e0\u5e8f\u5217\u65f6(\u91cd\u65b0\u6392\u5e8f)\u3002\u8fd9\u7c7b\u4e8b\u4ef6\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u514b\u670d\u4e86\u514d\u75ab\u529b\uff0c\u5e76\u5f15\u53d1\u4e86\u5168\u7403\u5927\u6d41\u884c\u3002<\/span><\/p>\n<\/section>\n

\n


<\/p>\n

\u6d41\u611f\u75ab\u82d7\u53ef\u6709\u6548\u9884\u9632\u4e25\u91cd\u5e76\u53d1\u75c7\u9ad8\u5371\u4eba\u7fa4(\u5982\u60a3\u6709\u6162\u6027\u80f8\u90e8\u75be\u75c5\u7684\u60a3\u8005)\u611f\u67d3\u3002\u5e38\u89c4\u7684\u6d41\u611f\u75ab\u82d7\u4f7f\u7528\u7684\u662f\u6740\u6b7b\u4e86\u7684\u6d41\u611f\u75c5\u6bd2\uff0c\u6d41\u611f\u75c5\u6bd2\u5728\u9e21\u86cb\u4e2d\u751f\u957f\uff0c\u7136\u540e\u88ab\u6740\u6b7b\u548c\u63d0\u7eaf\uff1b\u8fd8\u6709\u4e00\u79cd\u6d3b\u75ab\u82d7\u53ef\u4ee5\u55b7\u6d12\u5230\u9f3b\u5b50\u91cc\uff0c\u9664\u4e86\u514d\u75ab\u7403\u86cb\u767dIgG\u5916\uff0c\u8fd8\u53ef\u4ee5\u8bf1\u5bfc\u4fdd\u62a4\u6027IgA\u6297\u4f53\u3002<\/span>
<\/p>\n

\u6d41\u611f\u75ab\u82d7\u5fc5\u987b\u542b\u6709\u6700\u65b0\u7684\u6bd2\u682a\u624d\u80fd\u6709\u6548\u3002\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u4e3a\u75ab\u82d7\u5236\u9020\u5546\u63d0\u4f9b\u6709\u5173\u75c5\u6bd2\u53d8\u5316\u7684\u65e9\u671f\u9884\u8b66\u3002\u75ab\u82d7\u5236\u9020\u5546\u57281\u6708\u4efd\u9009\u62e9\u8981\u5305\u62ec\u5728\u75ab\u82d7\u4e2d\u7684\u75c5\u6bd2\uff0c\u5728\u63a5\u4e0b\u6765\u76846\u4e2a\u6708\u91cc\uff0c\u9009\u5b9a\u7684\u75c5\u6bd2\u5728\u9e21\u86cb\u4e0a\u751f\u957f\uff0c\u76f4\u5230\u6709\u8db3\u591f\u7684\u75c5\u6bd2\u5f00\u59cb\u751f\u4ea7\u75ab\u82d7\u3002\u8fd9\u4e00\u8fc7\u7a0b\u8981\u6c42\u75c5\u6bd2\u5236\u9020\u5546\u5728\u6bcf\u5e74\u6625\u5b63\u83b7\u53d6\u6570\u5343\u4e07\u679a\u5375\u5b50\u3002\u5230\u4e86\u590f\u5929\uff0c\u5982\u679c\u751f\u4ea7\u6309\u8ba1\u5212\u8fdb\u884c\uff0c\u75ab\u82d7\u5c31\u53ef\u4ee5\u8fdb\u884c\u6d4b\u8bd5\u4e86\u3002\u5982\u679c\u75ab\u82d7\u901a\u8fc7\u4e86\u5b89\u5168\u6027\u6d4b\u8bd5\uff0c\u90a3\u4e48\u5b83\u5c31\u53ef\u4ee5\u5206\u53d1\u7ed9\u4f7f\u7528\u8005\u3002<\/p>\n

\u5728\u5927\u591a\u6570\u5e74\u4efd\uff0c\u6709\u8db3\u591f\u7684\u6d41\u611f\u75c5\u6bd2\u8f7b\u5fae\u6f02\u79fb\u7684\u9884\u8b66\uff0c\u4ee5\u4fbf\u751f\u4ea7\u6700\u65b0\u7684\u75ab\u82d7\u3002\u7136\u800c\uff0c\u5982\u679c\u4e00\u79cd\u65b0\u75c5\u6bd2\u5728\u4e0e\u79bd\u6d41\u611f\u91cd\u7ec4\u540e\u901a\u8fc7\u6297\u539f\u8f6c\u79fb\u51fa\u73b0\uff0c\u5236\u9020\u5546\u53ef\u80fd\u9700\u8981\u957f\u8fbe10\u4e2a\u6708\u7684\u65f6\u95f4\u6765\u51c6\u5907\u65b0\u75ab\u82d7\u3002\u5728\u5927\u89c4\u6a21\u822a\u7a7a\u65c5\u884c\u7684\u65f6\u4ee3\uff0c\u8fd9\u79cd\u8f6c\u79fb\u7684\u75c5\u6bd2\u53ef\u80fd\u5728\u8fd9\u4e2a\u65f6\u5019\u5df2\u7ecf\u5728\u4e16\u754c\u5404\u5730\u4f20\u64ad\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\n

BOX 25.4<\/span>\u759f\u75be\u75ab\u82d7<\/span><\/p>\n<\/section>\n<\/section>\n

\n
\n
<\/svg><\/section>\n<\/section>\n
\n
<\/svg><\/section>\n<\/section>\n<\/section>\n
\n
\n

\u6bcf\u5e74\u7ea6\u6709100\u4e07\u4eba\u6b7b\u4e8e\u759f\u75be\u3002\u5b83\u662f\u7531\u539f\u751f\u52a8\u7269\u759f\u539f\u866b\u5f15\u8d77\u7684\uff0c\u759f\u539f\u866b\u901a\u8fc7\u868a\u5b50\u53ee\u54ac\u6ce8\u5165\u4eba\u4f53\u8840\u6db2\u4e2d\u3002\u759f\u539f\u866b\u6700\u521d\u5728\u809d\u810f\u4e2d\u7e41\u6b96\uff0c\u7136\u540e\u6539\u53d8\u5176\u5f62\u6001\uff0c\u5e76\u5728\u7ea2\u7ec6\u80de\u4e2d\u7ecf\u5386\u51e0\u4e2a\u7e41\u6b96\u5468\u671f\u3002\u76f4\u5230\u7ea2\u7ec6\u80de\u88ab\u611f\u67d3\uff0c\u75c7\u72b6\u624d\u4f1a\u51fa\u73b0\u3002\u5728\u8fd9\u4e00\u70b9\u4e0a\uff0c\u868a\u5b50\u53ee\u54ac\u53ef\u80fd\u4f1a\u611f\u67d3\u868a\u5b50\uff0c\u539f\u751f\u52a8\u7269\u5728\u518d\u6b21\u611f\u67d3\u53e6\u4e00\u4e2a\u4eba\u4e4b\u524d\uff0c\u4f1a\u6539\u53d8\u81ea\u5df1\u7684\u5f62\u6001\u5e76\u518d\u6b21\u7e41\u6b96\u3002<\/span>
<\/p>\n

\u9057\u4f20\u4e86\u5bfc\u81f4\u9570\u72b6\u7ec6\u80de\u7279\u5f81\u7684\u8840\u7ea2\u86cb\u767d\u57fa\u56e0\u591a\u6001\u6027\u7684\u4e2a\u4f53\u5bf9\u759f\u75be\u6709\u4e00\u5b9a\u7a0b\u5ea6\u7684\u514d\u75ab\uff08\u89c1BOX 3.1<\/span>)\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u5927\u591a\u6570\u4e2a\u4f53\u5bf9\u759f\u539f\u866b\u51e0\u4e4e\u6ca1\u6709\u9632\u5fa1\u80fd\u529b\u3002\u8fd9\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u662f\u56e0\u4e3a\u759f\u539f\u866b\u5728\u751f\u547d\u5468\u671f\u7684\u6bcf\u4e2a\u4e0d\u540c\u9636\u6bb5\u90fd\u5b58\u5728\u76f8\u5f53\u5927\u7684\u6297\u539f\u6027\u5dee\u5f02\u3002\u4e0e\u5927\u591a\u6570\u5176\u4ed6\u75c5\u539f\u4f53\u4e0d\u540c\uff0c\u81ea\u7136\u611f\u67d3\u4e0d\u4f1a\u5bfc\u81f4\u706d\u83cc\u514d\u75ab\u3002\u8fd9\u610f\u5473\u7740\u4ece\u759f\u75be\u4e2d\u5eb7\u590d\u7684\u4eba\u53ef\u80fd\u4f1a\u7ecf\u5386\u8fdb\u4e00\u6b65\u7684\u6025\u6027\u611f\u67d3\uff0c\u5c3d\u7ba1\u7a0b\u5ea6\u7a0d\u8f7b\u3002\u968f\u7740\u65f6\u95f4\u7684\u63a8\u79fb\uff0c\u5982\u679c\u4e2a\u4eba\u4e0d\u518d\u66b4\u9732\u4e8e\u759f\u75be\uff0c\u4ed6\u4eec\u5c06\u5931\u53bb\u6240\u6709\u66fe\u7ecf\u7684\u514d\u75ab\u529b\uff0c\u5e76\u5728\u518d\u6b21\u66b4\u9732\u65f6\u9762\u4e34\u4e25\u91cd\u611f\u67d3\u7684\u98ce\u9669\u3002<\/p>\n

\u4e8b\u5b9e\u8bc1\u660e\uff0c\u5f00\u53d1\u759f\u75be\u75ab\u82d7\u975e\u5e38\u5177\u6709\u6311\u6218\u6027\u3002\u73af\u5b50\u5b62\u5b50\u86cb\u767d(CSP)\u5df2\u88ab\u786e\u5b9a\u4e3a\u4e00\u79cd\u6709\u7528\u7684\u75ab\u82d7\u6297\u539f\u3002CSP\u88ab\u759f\u539f\u866b\u7528\u6765\u5bf9\u63a5\u5728\u809d\u7ec6\u80de\u4e0a\uff0c\u800c\u6297CSP\u7684\u6297\u4f53\u53ef\u4ee5\u7834\u574f\u751f\u547d\u5468\u671f\u7684\u8fd9\u4e00\u90e8\u5206\u3002CSP\u7684\u4f18\u70b9\u662f\u4e0d\u4f1a\u56e0\u4e0d\u540c\u7684\u759f\u539f\u866b\u83cc\u682a\u800c\u6709\u6240\u4e0d\u540c\u3002CSP\u86cb\u767d\u4e0e\u4e59\u578b\u809d\u708e\u8868\u9762\u6297\u539f(HBsAg)\u7ed3\u5408\u8868\u8fbe\uff0cCSP-HBsAg\u878d\u5408\u86cb\u767d\u5f62\u6210\u75c5\u6bd2\u6837\u9897\u7c92(VLP)\u4ee5\u589e\u5f3a\u514d\u75ab\u5e94\u7b54\uff0c\u8fd8\u6dfb\u52a0\u4e86\u4f50\u5242\u5355\u78f7\u8102(MPL)(Fig 25.7<\/span>)\u3002\u4f46\u5373\u4f7f\u6709\u4e86\u8fd9\u4e9b\u6539\u8fdb\uff0c\u76ee\u524d\u7684\u759f\u75be\u75ab\u82d7\u5728\u9884\u9632\u63a5\u79cd\u75ab\u82d7\u7684\u513f\u7ae5\u6025\u6027\u759f\u75be\u65b9\u9762\u4e5f\u53ea\u670950%\u5de6\u53f3\u7684\u6548\u529b\u3002<\/p>\n<\/section>\n<\/section>\n

\n
<\/section>\n<\/section>\n
\n

Fig 25.7<\/span> \u759f\u75be\u75ab\u82d7<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\u672c\u6587\u7531Oncolab\u5b9e\u9a8c\u5ba4\u5fae\u4fe1\u516c\u4f17\u53f7\u7ffb\u8bd1\u6574\u7406\u81eaImmunology for Medical Students\uff0c\u4ec5\u7528\u4e8e\u5b66\u4e60\u4ea4\u6d41\u4f7f\u7528\uff0c\u5982\u9700\u8d2d\u4e70\u539f\u7248\u4e66\u7c4d\u53ef\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8d2d\u4e70\u3002<\/span>
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\u2014 THE  END \u2014<\/span><\/p>\n


<\/p>\n

\u6765\u6e90 | Immunology for Medical Students<\/span><\/section>\n
\u7ffb\u8bd1 |   \u9648\u4f73\u8587 \u7f57\u6e05\u7075 <\/span><\/section>\n
\u521d\u5ba1 | \u9648\u79cb\u8c37 \u5b8b\u4e50<\/span><\/section>\n
\u7ec8\u5ba1 | \u738b\u5764<\/span> \u8096\u5efa\u52c7<\/span><\/section>\n
\uff08\u8f6c\u8f7d\u8bf7\u4fdd\u7559\u6b64\u90e8\u5206\u5185\u5bb9\uff09<\/span><\/strong><\/section>\n


<\/p>\n


<\/p>\n

\u2589  \u5f80\u671f\u6587\u7ae0\u76ee\u5f55<\/strong><\/strong><\/span><\/p>\n

\u57fa\u7840\u514d\u75ab\u5b66\u7cfb\u5217<\/span><\/strong><\/strong><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c24\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u4e2d\u7684\u7ec6\u80de\u56e0\u5b50<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c23\u7ae0\uff1a\u708e\u75c7\u4e0e\u514d\u75ab<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c22\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u6740\u4f24\u529f\u80fd<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c21\u7ae0\uff1a\u541e\u566c\u7ec6\u80de<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c20\u7ae0\uff1a\u56fa\u6709\u514d\u75ab\u7684\u9632\u5fa1\u4f5c\u7528<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c19\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u751f\u7406\u529f\u80fd\u7b80\u8ff0<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c18\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u8c03\u8282<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c17\u7ae0\uff1a\u514d\u75ab\u8bb0\u5fc6\u4e0e\u6dcb\u5df4\u7ec6\u80de\u7a33\u6001<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c16\u7ae0\uff1aT\u7ec6\u80de\u4e0e\u5176\u4ed6\u514d\u75ab\u7ec6\u80de\u95f4\u7684\u76f8\u4e92\u4f5c\u7528<\/span><\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c15\u7ae0\uff1aT\u7ec6\u80de\u7684\u53d1\u80b2<\/span><\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c14\u7ae0\uff1aB\u7ec6\u80de\u7684\u53d1\u80b2<\/span><\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c13\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u5668\u5b98\u548c\u7ec4\u7ec7<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c12\u7ae0\uff1a\u9020\u8840\u529f\u80fd-\u8840\u7ec6\u80de\u751f\u6210<\/span><\/a>
<\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c11\u7ae0\uff1a\u6dcb\u5df4\u7ec6\u80de\u6d3b\u5316<\/span><\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c10\u7ae0\uff1a\u6297\u539f\u7684\u5904\u7406\u548c\u5448\u9012<\/span><\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c9\u7ae0\uff1a\u6297\u539f\u8bc6\u522b\u7814\u7a76\u8fdb\u5c55<\/span><\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c8\u7ae0\uff1a\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u7269MHC<\/span><\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c7\u7ae0\uff1aT\u7ec6\u80de\u53d7\u4f53(TCR)\u6982\u8ff0<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c6\u7ae0\uff1a\u6297\u4f53\u591a\u6837\u6027<\/span><\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c5\u7ae0\uff1a\u6297\u4f53-\u6297\u539f\u76f8\u4e92\u4f5c\u7528<\/span><\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c4\u7ae0\uff1a\u6297\u539f\u548c\u6297\u4f53\u7ed3\u6784<\/span><\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c3\u7ae0\uff1a\u6297\u539f\u8bc6\u522b<\/span><\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c2\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u57fa\u672c\u6982\u5ff5\u548c\u7ec4\u6210<\/span><\/a><\/span>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c1\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7b80\u4ecb<\/span><\/a><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66\u7cfb\u5217<\/span><\/strong><\/strong><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c4\u7ae0\uff1a\u80bf\u7624\u4e2d\u7684\u7a81\u53d8\u8868\u4f4d\uff08\u4e0b\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c4\u7ae0\uff1a\u80bf\u7624\u4e2d\u7684\u7a81\u53d8\u8868\u4f4d\uff08\u4e0a\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c3\u7ae0\uff1aCD8+ T\u7ec6\u80de\u5728\u514d\u75ab\u6cbb\u7597\u3001\u653e\u7597\u548c\u5316\u7597\u4e2d\u7684\u4f5c\u7528\uff08\u4e0b\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c3\u7ae0\uff1aCD8+ T\u7ec6\u80de\u5728\u514d\u75ab\u6cbb\u7597\u3001\u653e\u7597\u548c\u5316\u7597\u4e2d\u7684\u4f5c\u7528\uff08\u4e0a\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c2\u7ae0\uff1a\u4eba\u7c7b\u80bf\u7624\u5fae\u73af\u5883\uff08\u4e0b\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c2\u7ae0\uff1a\u4eba\u7c7b\u80bf\u7624\u5fae\u73af\u5883\uff08\u4e0a\uff09<\/a><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c1\u7ae0\uff1a\u80bf\u7624\u514d\u75ab\u7b80\u53f2<\/span><\/a>
<\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66\u7cfb\u5217\u66f4\u65b0\u9884\u544a<\/span><\/a>
<\/span><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0\u7cfb\u5217<\/span><\/strong><\/strong><\/span><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c7\u5929)-210608<\/span><\/a>
<\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c6\u5929)-210607<\/span><\/a>
<\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c5\u5929)-210605<\/span><\/a>
<\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c4\u5929)-210604<\/span><\/a><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c3\u5929)-210603<\/span><\/a>
<\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c1\u5929)-20210531<\/span><\/a><\/span><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c2\u5929)-20210601<\/span><\/a><\/p>\n

TCGA\u514d\u75ab\u6d78\u6da6\u8bc4\u4ef7\u6570\u636e\u5e93<\/span><\/a>
<\/p>\n

ggplot2|\u8be6\u89e3\u516b\u5927\u57fa\u672c\u7ed8\u56fe\u8981\u7d20<\/span><\/a>
<\/p>\n

Python\u96c6\u6210\u5f00\u53d1\u73af\u5883PyCharm\u7684\u5b89\u88c5\u4e0e\u6fc0\u6d3b<\/span><\/a>
<\/p>\n

Python\u53d1\u884c\u7248Anaconda\u7684\u5b89\u88c5\u4e0e\u4f7f\u7528<\/span><\/a><\/p>\n

\u57fa\u7840\u5b9e\u9a8c\u6280\u672f\u7cfb\u5217<\/span><\/strong><\/strong><\/span><\/p>\n

\u6d41\u5f0f\u68c0\u6d4b\u7ec6\u80de\u603bROS-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/span>
<\/p>\n

Annexin V\/PI\u67d3\u8272\u68c0\u6d4b\u7ec6\u80de\u51cb\u4ea1-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a>
<\/p>\n

\u514d\u75ab\u8367\u5149\u5b9e\u9a8c-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a>
<\/p>\n

WB\u64cd\u4f5c\u89c6\u9891-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a><\/span><\/p>\n

QPCR\u5b9e\u9a8c\u64cd\u4f5c\u89c6\u9891-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a>
<\/p>\n

\u4eea\u5668\u64cd\u4f5c\u7cfb\u5217<\/span><\/strong><\/strong><\/span><\/p>\n

\u5c0f\u52a8\u7269\u6d3b\u4f53\u5149\u5b66\u6210\u50cf\u7cfb\u7edf\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a>
<\/p>\n

\u8521\u53f8LSM800\u6fc0\u5149\u5171\u805a\u7126\u663e\u5fae\u955c\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a>
<\/p>\n

IN Cell Analyzer2200\u9ad8\u5185\u6db5\u7ec6\u80de\u6210\u50cf\u5206\u6790\u7cfb\u7edf\u64cd\u4f5c\u6559\u7a0b-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a>
<\/p>\n

BD LSR Fortessa\u6d41\u5f0f-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/span><\/a><\/span><\/p>\n

\u6587\u732e\u5206\u4eab\u7cfb\u5217<\/span><\/strong><\/strong><\/span><\/p>\n

\u80bf\u7624\u4ee3\u8c22\u91cd\u7f16\u7a0b\u4e0e\u514d\u75ab\u5e94\u7b54<\/span><\/a>
<\/p>\n

\u5e74\u5ea6\u5de8\u732e\uff1a\u795e\u520aCA\u53d1\u5e03\u6700\u65b0\u764c\u75c7\u6570\u636e\uff1a\u5168\u74031000\u4e07\u4eba\u6b7b\u4e8e\u764c\u75c7\uff0c\u4e2d\u56fd\u5360\u6bd4\u8d853\u6210<\/span><\/a>
<\/p>\n

HLA-I\u5206\u5b50\u52a0\u5de5\u548c\u9012\u5448\u6297\u539f\u529f\u80fd\u53d7\u635f\u662f\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8010\u836f\u7684\u91cd\u8981\u539f\u56e0<\/span><\/a>
<\/p>\n

PD-1\/PD-L1\u963b\u65ad\u5242\u6cbb\u7597\u80bf\u7624\u7684\u7814\u7a76\u8fdb\u5c55\u4e0e\u9762\u4e34\u7684\u6311\u6218<\/span><\/a><\/span><\/p>\n

I<\/span>m<\/span>m<\/span>u<\/span>n<\/span>i<\/span>t<\/span>y<\/span>\uff1a<\/span>\u80bf<\/span>\u7624<\/span>\u514d<\/span>\u75ab<\/span>\u6cbb<\/span>\u7597<\/span>\u7684<\/span>\u5341<\/span>\u5927<\/span>\u6311<\/span>\u6218<\/span><\/span><\/a><\/p>\n

\u4f5c\u56fe\u6295\u7a3f\u9009\u520a\u7cfb\u5217<\/span><\/strong><\/strong><\/span><\/p>\n

GraphPad+AI\u5236\u4f5c\u53ef\u53d1\u8868\u7ea7\u522b\u7684\u67f1\u72b6\u56fe-OncoLab\u5b9e\u9a8c\u5ba4<\/span><\/a>
<\/p>\n

\u5982\u4f55\u4f7f\u7528ImageJ\u8fdb\u884c\u7ec6\u80de\u8367\u5149\u5b9a\u91cf<\/span><\/a>
<\/p>\n

\u5982\u4f55\u4f7f\u7528Scrivener\u8fdb\u884c\u79d1\u6280\u8bba\u6587\u5199\u4f5c<\/span><\/a>
<\/p>\n

Mendeley-\u6700\u597d\u7528\u7684\u6587\u732e\u9605\u8bfb\u7ba1\u7406\u8f6f\u4ef6\uff0c\u6ca1\u6709\u4e4b\u4e00<\/span><\/a>
<\/p>\n

\u5982\u4f55\u9009\u62e9\u4e00\u4e2a\u5408\u9002\u7684\u6742\u5fd7\u8fdb\u884c\u6295\u7a3f\uff1f<\/span><\/a>
<\/p>\n

PubMed\u4e2d\u5982\u4f55\u6309\u5f71\u54cd\u56e0\u5b50\u7b5b\u9009\u68c0\u7d22\u7ed3\u679c\u5e76\u663e\u793a\u5f71\u54cd\u56e0\u5b50\u53ca\u5206\u533a\uff1f<\/span><\/a>
<\/p>\n

\u5982\u4f55\u4f7f\u7528EndNote\u8f6f\u4ef6\u63d2\u5165\u53c2\u8003\u6587\u732e\uff08\u96446813\u79cd\u6742\u5fd7\u53c2\u8003\u6587\u732e\u683c\u5f0f\u6587\u4ef6\uff09<\/span><\/a><\/span><\/p>\n

\u4e2d\u533b\u4e2d\u836f\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u516b\u6bb5\u9526\uff08\u89c6\u9891\u7248+\u56fe\u7247\u7248\uff0c\u63a8\u8350\u6536\u85cf\uff09<\/span><\/a>
<\/p>\n

\u4e2d\u6210\u836f\u4f20\u7edf\u65b9\u5242\u4ea4\u53c9\u68c0\u7d22\u6570\u636e\u5e93\u4f7f\u7528\u8bf4\u660e<\/span><\/a><\/p>\n


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\u5173<\/span>\u6ce8<\/span>\u672c<\/span>\u53f7<\/span>~<\/span><\/span><\/p>\n


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\u52a0<\/span>\u5165<\/span>\u8bfb<\/span>\u8005<\/span>\u4ea4<\/span>\u6d41<\/span>\u7fa4<\/span>~<\/span><\/span><\/p>\n


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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u70b9<\/span>\u4eae<\/span>\u201c<\/span>\u5728<\/span>\u770b<\/span>\u201d<\/span><\/span><\/section>\n
\u8ba9<\/span>\u66f4<\/span>\u591a<\/span>\u4eba<\/span>\u770b<\/span>\u5230<\/span>\uff01<\/span><\/span><\/section>\n<\/section>\n
\n

\u672c\u7bc7\u6587\u7ae0\u6765\u6e90\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7: OncoLab <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u65b0\u5e74\u65b0\u6c14\u8c61\uff0c\u795d\u5927\u5bb6\u5728\u65b0\u7684\u4e00\u5e74\u91cc\u4e07\u4e8b\u987a\u9042\uff0c\u8eab\u4f53\u5065\u5eb7~ \u5bfc \u8bfb \u672c\u7ae0\u8ba8\u8bba\u75c5\u539f\u4f53\u7528\u6765\u9003\u907f\u514d\u75ab\u76d1\u6d4b\u7684\u673a\u5236\u4ee5\u53ca\u4e09\u79cd\u4e3b\u8981\u7c7b…<\/p>\n","protected":false},"author":1,"featured_media":1899,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[64],"tags":[],"_links":{"self":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/1900"}],"collection":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/comments?post=1900"}],"version-history":[{"count":0,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/1900\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/media\/1899"}],"wp:attachment":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/media?parent=1900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/categories?post=1900"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/tags?post=1900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}