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\u6d89\u53ca\u8fc7\u654f\u7684\u4e3b\u8981\u7ec6\u80de\u662f\u80a5\u5927\u7ec6\u80de\u548c\u55dc\u9178\u6027\u7c92\u7ec6\u80de<\/span>\uff0c\u8fd9\u4e2a\u5df2\u7ecf\u5728\u7b2c22\u7ae0<\/span>\u4e2d\u8fdb\u884c\u4e86\u63cf\u8ff0\uff0c\u5176\u4e2d\u4ecb\u7ecd\u4e86\u8fd9\u4e9b\u7ec6\u80de\u662f\u5982\u4f55\u5206\u5316\u5e76\u6740\u6b7b\u5bc4\u751f\u866b\u7684\u3002\u80a5\u5927\u7ec6\u80de\u5b58\u5728\u4e8e\u8bb8\u591a\u7ec4\u7ec7\u4e2d\uff0c\u800c\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u4f1a\u8fc1\u79fb\u5230\u2160\u578b\u8d85\u654f\u53cd\u5e94\u53d1\u751f\u7684\u7ec4\u7ec7\u4e2d\uff0c\u8fd9\u4e9b\u7ec6\u80de\u91ca\u653e\u7684\u4ecb\u8d28\u53ef\u5f15\u8d77\u8fc7\u654f\u3002\u7b2c\u4e09\u79cd\u8131\u9897\u7c92\u7ec6\u80de\u662f\u55dc\u78b1\u6027\u7c92\u7ec6\u80de\u3002\u5b83\u4eec\u7684\u5916\u89c2\u4e0e\u80a5\u5927\u7ec6\u80de\u76f8\u4f3c\uff0c\u4f46\u76ee\u524d\u4ecd\u4e0d\u77e5\u9053\u5b83\u4eec\u662f\u5426\u6709\u7279\u6b8a\u529f\u80fd\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u80a5\u5927\u7ec6\u80de\u819c\u4e0a\u6709Fc\u03b5RI (\u9ad8\u4eb2\u548c\u6027\u7684IgE\u53d7\u4f53)\u3002\u5f53\u6297\u539f\u901a\u8fc7 Fc\u03b5RI\u4e0e\u540c\u7ec6\u80de\u7ed3\u5408\u7684 IgE \u4ea4\u8054\u65f6\uff0c\u80a5\u5927\u7ec6\u80de\u88ab\u6fc0\u6d3b\uff0c\u91ca\u653e\u65e9\u671f\u53cd\u5e94\u7684\u4ecb\u8d28(Fig 27.1<\/span>)\u3002\u6b64\u5916\uff0c\u80a5\u5927\u7ec6\u80de\u3001\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u548c\u55dc\u78b1\u6027\u7c92\u7ec6\u80de\u4e5f\u53ef\u4ee5\u88ab\u5176\u4ed6\u4fe1\u53f7\u523a\u6fc0\u6fc0\u6d3b\u3002\u4f8b\u5982\uff0c\u611f\u67d3\u4ea7\u751f\u7684\u6fc0\u6d3b\u8865\u4f53\u53ef\u4ee5\u6fc0\u6d3b\u80a5\u5927\u7ec6\u80de\u3002\u8fd8\u53ef\u4ee5\u50cf\u795e\u7ecf\u7cfb\u7edf\u4f20\u9012\u7684\u4fe1\u53f7\u4e00\u6837\u88ab\u6fc0\u6d3b\uff0c\u4f8b\u5982\uff0c\u5bf9\u6e29\u5ea6\u53d8\u5316\u7684\u53cd\u5e94\u3002\u672c\u7ae0\u540e\u9762\u5c06\u4f1a\u8be6\u7ec6\u63cf\u8ff0\u9664\u4e86\u8fc7\u654f\u5916\uff0c\u7531\u5176\u4ed6\u6761\u4ef6\u5f15\u8d77\u7684\u75c7\u72b6(Table 27.1<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
<\/section>\n<\/section>\n
\n
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\n


<\/p>\n<\/section>\n<\/section>\n

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\n

Fig 27.1<\/span> IgE\u4e0e\u80a5\u5927\u7ec6\u80de\u4e0a\u7684Fc\u03b5R\u7ed3\u5408\u3002\u5f53\u8fc7\u654f\u539f\u4e0eIgE\u5206\u5b50\u4ea4\u8054\u65f6\uff0c\u80a5\u5927\u7ec6\u80de\u88ab\u6fc0\u6d3b\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/section>\n<\/section>\n
\n
\n
\n


<\/p>\n<\/section>\n<\/section>\n

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\n

Table 27.1 <\/span>\u8fc7\u654f\u6027\u75be\u75c5<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n

\n
\n

\u6297\u4f53<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

IgE \u662f I \u578b\u8d85\u654f\u53cd\u5e94\u6240\u5fc5\u9700\u7684\u3002\u5f53B\u7ec6\u80de\u88abTH2\u7ec6\u80de\u5206\u6ccc\u7684IL-4\u523a\u6fc0\u65f6\uff0c\u5b83\u4eec\u4f1a\u4ea7\u751fIgE\u3002\u4ea7\u751f\u7684IgE\u4f1a\u4e0e\u9ad8\u4eb2\u548c\u529b\u53d7\u4f53Fc\u03b5RI\u7ed3\u5408\uff0cFc\u03b5RI\u901a\u5e38\u5728\u7ec4\u7ec7\u4e2d\u7684\u80a5\u5927\u7ec6\u80de\u548c\u5df2\u88ab\u6fc0\u6d3b\u5e76\u8fc1\u79fb\u5230\u7ec4\u7ec7\u4e2d\u7684\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u4e0a\u8868\u8fbe(\u89c1Fig 27.1<\/span>)\u3002\u5c3d\u7ba1\u8840\u6e05\u4e2dIgE\u7684\u6d53\u5ea6\u6bd4IgG\u4f4e\u5343\u500d\uff0c\u4f46\u7531\u4e8eIgE\u4e0eFc\u03b5RI\u4e4b\u95f4\u5177\u6709\u5f88\u9ad8\u7684\u4eb2\u548c\u529b\uff0cIgE\u4f1a\u4e0d\u65ad\u5730\u4e0e\u80a5\u5927\u7ec6\u80de\u4e0a\u7684Fc\u03b5RI\u7ed3\u5408\u4ee5\u5bf9\u6297\u4e0d\u540c\u7684\u6297\u539f\u3002
<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u5728\u611f\u67d3\u5bc4\u751f\u866b(\u5982\u8840\u5438\u866b\u75c5)\u7684\u60a3\u8005\u548c\u9057\u4f20\u4e86\u5f02\u4f4d\u6027\u7279\u5f81\u7684\u4eba\u7fa4\u4e2d\uff0c\u603bIgE\u6c34\u5e73\u975e\u5e38\u9ad8\u3002\u5728\u8c03\u67e5\u8fc7\u654f\u75c7\u72b6\u7684\u539f\u56e0\u65f6\uff0c\u53ef\u4f7f\u7528\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u6216\u9176\u8054\u514d\u75ab\u5438\u9644\u8bd5\u9a8c(ELISA)\u6d4b\u5b9a\u9488\u5bf9\u7279\u5b9a\u8fc7\u654f\u539f\u7684IgE\u6c34\u5e73\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n


<\/p>\n<\/section>\n<\/section>\n

\n
\n

\u8f85\u52a9\u6027T\u7ec6\u80de2(TH2)<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u4eba\u7c7b\u5927\u591a\u6570\u9002\u5e94\u6027\u514d\u75ab\u7cfb\u7edf\u53cd\u5e94\u4f1a\u4ea7\u751f\u6297\u4f53\u548c\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de(CTL)\u7684\u6df7\u5408\u7269\u3002\u54ea\u79cd\u7c7b\u578b\u7684\u53cd\u5e94\u5360\u4e3b\u5bfc\u5730\u4f4d\u53d6\u51b3\u4e8e\u514d\u75ab\u7cfb\u7edf\u6240\u8bc6\u522b\u7684\u75c5\u539f\u4f53\u7c7b\u578b\u3002\u7b2c23\u7ae0<\/span>\u63cf\u8ff0\u4e86\u514d\u75ab\u7cfb\u7edf\u5982\u4f55\u5e94\u5bf9\u6162\u6027\u7ec6\u80de\u5185\u611f\u67d3\uff0c\u5982\u7ed3\u6838\u75c5(TB)\u4e3b\u8981\u901a\u8fc7\u4ea7\u751fTH1\uff0c\u5e76\u901a\u8fc7\u5e72\u6270\u7d20\u03b3 (IFN-\u03b3)\u6fc0\u6d3bCTL\u548c\u5de8\u566c\u7ec6\u80de\u3002TH1\u514d\u75ab\u53cd\u5e94\u4e2d\u4e5f\u4f1a\u4ea7\u751f\u9ad8\u6c34\u5e73\u7684IgG\u3002\u5982\u7b2c16\u7ae0<\/span>\u6240\u8ff0\uff0cTH17\u7ec6\u80de\u901a\u8fc7\u6fc0\u6d3b\u4e2d\u6027\u7c92\u7ec6\u80de\u548c\u523a\u6fc0\u4e0a\u76ae\u7ec6\u80de\u5206\u6ccc\u6297\u83cc\u80bd\u6765\u5e94\u5bf9\u7ec6\u80de\u5916\u7684\u611f\u67d3\u3002\u7136\u800c\uff0c\u8fc7\u654f\u9700\u8981\u4ea7\u751f\u5927\u91cf\u7684 IgE\uff0c\u800c\u8fd9\u53c8\u9700\u8981\u4ea7\u751f IL-4 \u7684 TH2 \u7ec6\u80de\u7684\u5e2e\u52a9\u3002\u5728 TH2 \u53cd\u5e94\u4e2d\uff0cIgG \u548c CTL \u7684\u4ea7\u751f\u53d7\u5230\u6291\u5236\u3002\u7ed3\u6838\u75c5\u548c\u8fc7\u654f\u4ee3\u8868\u4e86\u9002\u5e94\u6027\u514d\u75ab\u53cd\u5e94\u7684\u76f8\u53cd\u4e24\u6781\u3002 <\/p>\n

\u5927\u591a\u6570\u53cd\u5e94\u4e0d\u90a3\u4e48\u6781\u7aef\uff0c\u6d89\u53ca TH1\u3001TH17 \u548c TH2 \u7ec6\u80de\u7684\u6df7\u5408\u3002TH1\u6781\u5316\u7ec6\u80de\u7684\u7279\u70b9\u662f\u8868\u8fbe\u8f6c\u5f55\u56e0\u5b50TBX21\uff0c\u8be5\u8f6c\u5f55\u56e0\u5b50\u4f1a\u4fc3\u8fdbT\u7ec6\u80de\u5206\u6cccIFN-\u03b3\u3002\u6b64\u5916\uff0cTH17\u7ec6\u80de\u53d7\u8f6c\u5f55\u56e0\u5b50ROR\u03b3t\u7684\u8c03\u8282\u3002TH2\u7ec6\u80de\u8868\u8fbe\u8f6c\u5f55\u56e0\u5b50GATA3\uff0c\u8fdb\u800c\u4fc3\u8fdbIL-4\u53ca\u76f8\u5173\u7ec6\u80de\u56e0\u5b50IL-5\u548cIL-13\u7684\u5206\u6ccc\u3002\u6240\u6709CD4+ <\/sup>T\u7ec6\u80de\u90fd\u6765\u81eaT\u7ec6\u80de\u7684\u53d1\u80b2\u8fc7\u7a0b\u4e2d\uff0cT\u7ec6\u80de\u5177\u6709\u5411TH1\u3001TH17\u6216TH2\u65b9\u5411\u5206\u5316\u7684\u80fd\u529b\u3002\u8fd9\u79cd\u5206\u5316\u7684\u65b9\u5411\u53d6\u51b3\u4e8e\u8f6c\u5f55\u56e0\u5b50TBX21\u3001ROR\u03b3t\u6216GATA3\u662f\u5426\u6210\u4e3a\u663e\u6027\u8f6c\u5f55\u56e0\u5b50(\u89c1Box 16.1<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u7b2c\u56db\u79cdCD4+ <\/sup>T\u7ec6\u80de\u7684\u7c7b\u578b\u662f\u8c03\u8282\u6027T\u7ec6\u80de(Tregs;\u7b2c18\u7ae0<\/span>)\u3002Tregs\u5728\u5916\u5468\u8010\u53d7\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\uff0c\u5e76\u4ee5\u6297\u539f\u4f9d\u8d56\u7684\u65b9\u5f0f\u6291\u5236TH1\u548cTH2\u7ec6\u80de\u3002Tregs\u901a\u8fc7\u5206\u6ccc\u7ec6\u80de\u56e0\u5b50\u6291\u5236\u5176\u4ed6T\u7ec6\u80de\uff0c\u5982\u8f6c\u5316\u751f\u957f\u56e0\u5b50\u03b2 (TGF-\u03b2)\u548cIL-10\u3002Tregs\u7ec6\u80de\u4e5f\u53ef\u80fd\u5728\u611f\u67d3\u8fc7\u7a0b\u4e2d\u8d77\u4f5c\u7528\uff0c\u6bd4\u5982\u5b83\u4eec\u53ef\u4ee5\u9632\u6b62\u514d\u75ab\u8fc7\u5ea6\u5bfc\u81f4\u7684\u8fc7\u654f\u3002\u5728\u5927\u591a\u6570\u4eba\u4e2d\uff0cTregs\u53ef\u963b\u6b62\u8f85\u52a9\u6027T\u7ec6\u80de\u5bf9TH1 \u6216 TH2 \u7ec6\u80de\u56e0\u5b50\u4ea7\u751f\u7684\u6781\u7aef\u60c5\u51b5\u6240\u51fa\u73b0\u7684\u8fc7\u5ea6\u6781\u5316\u3002\u4f8b\u5982\uff0c\u5728\u975e\u8fc7\u654f\u7684\u4e2a\u4f53\u4e2d\uff0c\u7531\u4e8eTregs\u7684\u6291\u5236\u4f5c\u7528\uff0c\u673a\u4f53\u4e0d\u4f1a\u53d1\u751f\u5bf9\u73af\u5883\u8fc7\u654f\u539f\u7684\u6781\u5316\u53cd\u5e94\u3002\u6b64\u5916\uff0c\u5728\u8fc7\u654f\u7684\u4e2a\u4f53\u4e2d\u4e5f\u53ef\u4ee5\u8bf1\u5bfcTregs\u53d1\u6325\u6291\u5236TH1\u548cTH2\u7ec6\u80de\u7684\u4f5c\u7528\uff0c\u8fd9\u662f\u8fc7\u654f\u539f\u514d\u75ab\u6cbb\u7597\u7684\u57fa\u7840\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
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\n

\u5982\u7b2c16\u7ae0<\/span>\u6240\u8ff0\uff0c\u6297\u539f\u63d0\u5448\u7ec6\u80de(APCs)\u4f3c\u4e4e\u53ef\u4ee5\u51b3\u5b9aT\u7ec6\u80de\u662f\u5411TH1\u8fd8\u662fTH2\u5206\u5316\u3002\u539f\u56e0\u76ee\u524d\u5c1a\u4e0d\u6e05\u695a\uff0c\u4f46APC\u4f3c\u4e4e\u66f4\u6709\u5229\u4e8eT\u7ec6\u80de\u5411TH2\u7ec6\u80de\u7684\u5206\u5316\u3002\u5982\u679c\u6297\u539f\u5b58\u5728\u4e8e\u7c98\u819c\u8868\u9762\u6216\u4e0e\u523a\u6fc0APC\u4e0a\u7684\u7279\u5b9a\u6a21\u5f0f\u8bc6\u522b\u5206\u5b50\u6709\u5173\uff0cT\u7ec6\u80de\u5219\u66f4\u6709\u53ef\u80fd\u5411TH2\u7ec6\u80de\u7684\u5206\u5316\u3002\u4f8b\u5982\uff0c\u5728Tregs\u4e0d\u6291\u5236\u6781\u5316\u7684\u524d\u63d0\u4e0b\uff0c\u523a\u6fc0T\u7ec6\u80de\u4e0a\u7684Toll\u6837\u53d7\u4f53 (TLR)\u4f1a\u8bf1\u5bfcT\u7ec6\u80deGATA3\u7684\u8868\u8fbe\uff0c\u4e14\u4ea7\u751f\u5c11\u91cf\u7684IL-4\u3002\u968f\u7740T\u7ec6\u80de\u7684\u589e\u6b96\uff0c\u4f1a\u66f4\u52a0\u5bb9\u6613\u4ea7\u751f\u8868\u89c2\u9057\u4f20\u7684\u53d8\u5316\uff0c\u6700\u7ec8\u5b50\u4ee3T\u7ec6\u80de\u8d8b\u5411\u4e8eTH2\u8868\u578b\u7684\u6781\u5316\u3002\u7531\u6b64\u770b\u6765\uff0c\u523a\u6fc0TLR\u4f3c\u4e4e\u6709\u5229\u4e8eT\u7ec6\u80de\u5206\u5316\u4e3aTH2\u7ec6\u80de\u3002\u4e00\u65e6\u5efa\u7acbTH2\u514d\u75ab\u53cd\u5e94\uff0c\u9ad8\u6c34\u5e73\u7684IL-4\u5206\u6ccc\u5c06\u523a\u6fc0B\u7ec6\u80de\u4ea7\u751fIgE\u3002\u4ea7\u751f\u7684IgE\u4e0e\u80a5\u5927\u7ec6\u80de\u8868\u9762\u7684Fc\u03b5RI\u7ed3\u5408\u3002\u5982\u679c\u6297\u539f\u4e0eFc\u03b5RI\u7ed3\u5408\u7684IgE\u4ea4\u8054\uff0c\u80a5\u5927\u7ec6\u80de\u5c06\u4f1a\u91ca\u653eIL-4\uff0c\u8fd9\u4e3a\u4ea7\u751f\u66f4\u591a\u7684IgE\u548cTH2\u7ec6\u80de\u63d0\u4f9b\u4e86\u4e00\u4e2a\u6b63\u53cd\u9988\u7cfb\u7edf\u3002IL-4\u8fd8\u80fd\u6291\u5236TH1\u7ec6\u80de\u4ea7\u751fIFN-\u03b3\u3002\u56e0\u6b64\uff0c\u4e00\u65e6T\u7ec6\u80de\u5bf9\u6297\u539f\u7684\u53cd\u5e94\u5f71\u54cd\u4e86TH2\u7ec6\u80de\u4ea7\u751f\u7684\u7ec6\u80de\u56e0\u5b50\u7684\u6b63\u5e38\u6c34\u5e73\uff0c\u6b63\u53cd\u9988\u5c06\u4f1a\u7ef4\u6301\u5e76\u589e\u5f3a\u53cd\u5e94\u3002\u6b64\u5916\uff0cTH2\u7ec6\u80de\u5206\u6ccc\u5176\u4ed6\u7684\u7ec6\u80de\u56e0\u5b50(\u5982IL-5\u3001IL-13\u3001eotaxin)\u53ef\u901a\u8fc7\u523a\u6fc0\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u7684\u6210\u719f\u548c\u8fc1\u79fb\u4ee5\u53ca\u6291\u5236TH1\u7ec6\u80de\uff0c\u6765\u7ef4\u6301TH2\u7ec6\u80de\u7684\u8868\u8fbe\u6c34\u5e73(Fig 27.2<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/section>\n<\/section>\n
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<\/p>\n<\/section>\n<\/section>\n

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Fig 27.2<\/span> IL-5\u3001IL-4\u3001eotaxin\u5e2e\u52a9\u7ef4\u6301TH2\u514d\u75ab\u53cd\u5e94\u5e76\u6291\u5236TH1\u514d\u75ab\u53cd\u5e94\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u603b\u4e4b\uff0cAPCs\u80fd\u51b3\u5b9aT\u7ec6\u80de\u662f\u5426\u5411TH1\u3001TH17\u6216TH2\u7ec6\u80de\u65b9\u5411\u53d1\u5c55\uff0c\u4ece\u800c\u5f71\u54cdIL-4\u6216IFN-\u03b3\u7684\u8868\u8fbe\u3002\u5728\u5927\u591a\u6570\u5e94\u7b54\u8fc7\u7a0b\u4e2d\u4f1a\u4ea7\u751fTH1\u548cTH2\u7ec6\u80de\u7684\u6df7\u5408\u7269\uff0c\u5bf9\u4e8e\u54ea\u79cd\u5e94\u7b54\u5360\u4e3b\u5bfc\u5730\u4f4d\u53d6\u51b3\u4e8e\u89e6\u53d1\u611f\u67d3\u7684\u7c7b\u578b\u3002TH1\u548cTH2\u7ec6\u80de\u5bf9\u81ea\u8eab\u7ec6\u80de\u4ea7\u751f\u7684\u6b63\u53cd\u9988\u53ef\u80fd\u5bfc\u81f4\u514d\u75ab\u53cd\u5e94\u7684\u6781\u7aef\u6781\u5316\u3002Tregs\u901a\u5e38\u53ef\u4ee5\u963b\u6b62\u6781\u7aef\u6781\u5316\u3002\u5018\u82e5\u6ca1\u6709Tregs\uff0c\u514d\u75ab\u7cfb\u7edf\u53cd\u5e94\u53ef\u80fd\u8fc7\u5ea6\u6781\u5316\u81f3TH2\uff0c\u5e76\u53ef\u80fd\u53d1\u5c55\u6210\u8fc7\u654f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n

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\u8fc7\u654f\u6613\u611f\u6027<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u8fc7\u654f\u7684\u6d41\u884c\u75c5\u5b66\u7814\u7a76\u4e2d\u9700\u8981\u6e05\u695a\u4e09\u4e2a\u91cd\u8981\u7684\u5df2\u77e5\u4e8b\u5b9e\uff1a<\/p>\n

\u2022 \u8fc7\u654f\u662f\u975e\u5e38\u666e\u904d\u7684\uff0c\u5728\u53d1\u8fbe\u56fd\u5bb6\u4e2d\u9ad8\u8fbe40%\u7684\u4eba\u53e3\u53d7\u5176\u5f71\u54cd\u3002<\/span><\/p>\n

\u2022 \u9057\u4f20\u56e0\u7d20\u4f3c\u4e4e\u662f\u8fc7\u654f\u7684\u90e8\u5206\u539f\u56e0\u3002\u7814\u7a76\u8868\u660e80%\u7684\u8fc7\u654f\u98ce\u9669\u662f\u9057\u4f20\u7684\u3002\u53d7\u5f71\u54cd\u7684\u5bb6\u5ead\u6210\u5458\u53ef\u80fd\u5bf9\u4e0d\u540c\u7684\u8fc7\u654f\u539f\u6709\u4e0d\u540c\u7684\u8fc7\u654f\u53cd\u5e94\uff0c\u5982\u54ee\u5598\u3001\u82b1\u7c89\u70ed\u6216\u6e7f\u75b9\u3002<\/span><\/span><\/p>\n

\u2022 \u8bb8\u591a\u56fd\u5bb6\u8fc7\u654f\u7684\u53d1\u75c5\u7387\u5f00\u59cb\u589e\u52a0\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e86\u89e3\u8fd9\u4e9b\u6d41\u884c\u75c5\u5b66\u7684\u751f\u7269\u5b66\u57fa\u7840\u5c06\u6709\u52a9\u4e8e\u6211\u4eec\u9884\u9632\u548c\u6cbb\u7597\u8fc7\u654f\u3002\u63a5\u4e0b\u6765\u7684\u4e24\u8282\u8ba8\u8bba\u5df2\u77e5\u6709\u5173\u8fc7\u654f\u7684\u9057\u4f20\u56e0\u7d20\u548c\u73af\u5883\u56e0\u7d20\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u8fc7\u654f\u7684\u9057\u4f20\u56e0\u7d20<\/strong><\/p>\n<\/section>\n

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\u867d\u7136\u9057\u4f20\u56e0\u7d20\u662f\u8fc7\u654f\u7684\u90e8\u5206\u539f\u56e0\uff0c\u4f46\u4e0d\u53ef\u80fd\u5728\u6bcf\u4e2a\u53d7\u8fc7\u654f\u5f71\u54cd\u7684\u4eba\u8eab\u4e0a\u53d1\u73b0\u57fa\u56e0\u7a81\u53d8\u6216\u591a\u6001\u6027\u3002\u5176\u4e2d\u4e00\u4e9b\u7814\u7a76\u5df2\u7ecf\u8bc1\u5b9e\u4e0d\u540c\u57fa\u56e0\u7684\u591a\u6001\u6027\uff0c\u8fd9\u4e9b\u57fa\u56e0\u53ef\u80fd\u5171\u540c\u5f71\u54cd\u8fc7\u654f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u76ee\u524d\u5df2\u7ecf\u8bc1\u5b9e\u4e86\u4e1d\u805a\u86cb\u767d\u57fa\u56e0\u7684\u591a\u6001\u6027\u662f\u8fc7\u654f\u539f\u56e0\u4e4b\u4e00\u3002\u4e1d\u805a\u86cb\u767d\u662f\u4e00\u79cd\u5728\u76ae\u80a4\u89d2\u8d28\u5f62\u6210\u7ec6\u80de\u4e2d\u8868\u8fbe\u7684\u86cb\u767d\u8d28\u3002\u5b83\u5728\u76ae\u80a4\u89d2\u8d28\u5f62\u6210\u7ec6\u80de\u7684\u7ec6\u80de\u9aa8\u67b6\u4e2d\u8d77\u4e00\u5b9a\u7684\u4f5c\u7528\uff0c\u7279\u522b\u662f\u5728\u76ae\u80a4\u89d2\u8d28\u5f62\u6210\u7ec6\u80de\u4e4b\u95f4\u7684\u7d27\u5bc6\u8fde\u63a5\u5185\u548c\u5468\u56f4\uff0c\u53ef\u5e2e\u52a9\u7ef4\u6301\u4e0a\u76ae\u5c4f\u969c(Fig 27.3<\/span>)\u3002\u6b64\u5916\uff0c\u4e1d\u805a\u86cb\u767d\u53ef\u88ab\u5206\u89e3\u6210\u66f4\u5c0f\u7684\u80bd\uff0c\u8fd9\u4e9b\u80bd\u662f\u4e00\u79cd\u5929\u7136\u4fdd\u6e7f\u56e0\u5b50(NMF)\uff0c\u5177\u6709\u5438\u6e7f\u6027\u3002NMF\u6709\u52a9\u4e8e\u7ef4\u6301\u76ae\u80a4\u7684pH\u503c\u5728\u8f83\u4f4e\u6c34\u5e73\uff0c\u8fd9\u88ab\u8ba4\u4e3a\u6709\u5229\u4e8e\u9632\u6b62\u75c5\u539f\u4f53\u7684\u5165\u4fb5\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig 27.3 <\/span>\u4e1d\u805a\u86cb\u767d\u6709\u52a9\u4e8e\u7ef4\u6301\u76ae\u80a4\u5c4f\u969c\u548c\u6ecb\u6da6\u76ae\u80a4\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e1d\u805a\u86cb\u767d\u57fa\u56e0\u6709\u9ad8\u5ea6\u53d8\u5f02\u6027\uff0c\u8fd9\u4e9b\u53d8\u5f02\u88ab\u8ba4\u4e3a\u662f\u591a\u6001\u6027\uff0c\u56e0\u4e3a\u5b83\u53d1\u751f\u5728\u8d85\u8fc71%\u7684\u4eba\u7fa4\u4e2d\u3002\u53d8\u5f02\u540e\u4e1d\u805a\u86cb\u767d\u5728\u7ef4\u6301\u4e0a\u76ae\u5c4f\u969c\u6216\u6ecb\u6da6\u76ae\u80a4\u65b9\u9762\u6548\u679c\u8f83\u5dee\u3002\u4e1d\u805a\u86cb\u767d\u53d8\u5f02\u4e0e\u6240\u6709\u7c7b\u578b\u7684\u8fc7\u654f\u90fd\u6709\u5173\uff0c\u73af\u5883\u56e0\u7d20\u4f7f\u9057\u4f20\u4e86\u4e1d\u805a\u86cb\u767d\u53d8\u5f02\u7684\u513f\u7ae5\u6709\u8f83\u9ad8\u7684\u8fc7\u654f\u98ce\u9669\u3002\u4f8b\u5982\uff0c\u5bf9\u4e8e\u5e26\u6709\u4e1d\u805a\u86cb\u767d\u53d8\u5f02\u7684\u513f\u7ae5\uff0c\u65e9\u671f\u63a5\u89e6\u732b\u4f1a\u589e\u52a0\u5728\u4ee5\u540e\u751f\u6d3b\u4e2d\u60a3\u4e0a\u82b1\u7c89\u70ed(\u7531\u8349\u82b1\u7c89\u5f15\u8d77\u7684\u8fc7\u654f\u6027\u9f3b\u708e)\u7684\u98ce\u9669\u3002\u8fd9\u610f\u5473\u7740\u4e1d\u805a\u86cb\u767d\u53d8\u5f02\u4f1a\u5f15\u8d77\u514d\u75ab\u7cfb\u7edf\u7684\u7cfb\u7edf\u6027\u53d8\u5316\uff0c\u4ece\u800c\u5f71\u54cd\u5176\u4ed6\u5668\u5b98\u7cfb\u7edf\uff0c\u589e\u52a0\u5bf9\u5176\u4ed6\u8fc7\u654f\u539f\u7684\u654f\u611f\u6027\u3002\u7136\u800c\uff0c\u957f\u5927\u540e\u63a5\u89e6\u732b\u5374\u4e0d\u4f1a\u4ea7\u751f\u8fd9\u6837\u7684\u6548\u679c\u3002\u56e0\u6b64\uff0c\u66b4\u9732\u4e8e\u73af\u5883\u56e0\u7d20\u7684\u65f6\u673a\u4e5f\u662f\u81f3\u5173\u91cd\u8981\u7684\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5176\u4ed6\u514d\u75ab\u7cfb\u7edf\u57fa\u56e0\u7684\u53d8\u5f02\u4e5f\u4e0e\u8fc7\u654f\u6709\u5173\u3002\u4f8b\u5982\uff0c\u5bf9\u4e8e\u8bb8\u591a\u751f\u7269\u4f53\u4e2d\u91ca\u653e\u51fa\u6765\u7684\u8102\u591a\u7cd6(LPS)\uff0cCD14 \u57fa\u56e0\uff08LPS \u53d7\u4f53\uff09\u548c LPS \u6c34\u5e73\u7684\u53d8\u5f02\u76f8\u4e92\u4f5c\u7528\uff0c\u5bf9\u8fc7\u654f\u98ce\u9669\u4ea7\u751f\u6b63\u9762\u6216\u8d1f\u9762\u5f71\u54cd\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig 27.4<\/span>\u5217\u51fa\u4e86\u4e00\u4e2a\u5047\u8bbe\u7684\u65f6\u95f4\u8f74\uff0c\u8bf4\u660e\u4e86\u9057\u4f20\u548c\u73af\u5883\u56e0\u7d20\u5982\u4f55\u5728\u5173\u952e\u65f6\u95f4\u70b9\u76f8\u4e92\u4f5c\u7528\u5e76\u5bfc\u81f4\u8fc7\u654f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig 27.4 <\/span>\u8fc7\u654f\u662f\u5982\u4f55\u5728\u4e00\u4e2a\u4eba\u8eab\u4e0a\u53d1\u5c55\u7684\u7406\u8bba\u65f6\u95f4\u8868\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u73af\u5883\u56e0\u7d20\u4e0e\u8fc7\u654f<\/strong><\/p>\n<\/section>\n

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\u53d1\u8fbe\u56fd\u5bb6\u8fc7\u654f\u53d1\u75c5\u7387\u7684\u589e\u52a0\u8868\u660e\u4e86\u73af\u5883\u56e0\u7d20\u53d8\u5316\u5bf9\u8fc7\u654f\u7684\u5f71\u54cd\uff0c\u7279\u522b\u662f\u968f\u7740\u57ce\u5e02\u5316\u8fdb\u7a0b\u7684\u52a0\u5feb\uff0c\u8fc7\u654f\u53d1\u75c5\u7387\u589e\u52a0\u5e45\u5ea6\u8f83\u5927\u3002\u7814\u7a76\u8868\u660e\uff0c\u5728\u519c\u573a\u957f\u5927\u548c\u63a5\u89e6\u7272\u755c\u53ef\u4ee5\u964d\u4f4e\u8fc7\u654f\u98ce\u9669\u3002\u8fd9\u5bfc\u81f4\u4e86\u4e00\u79cd\u89c2\u70b9\uff0c\u5373\u63a5\u89e6\u52a8\u7269\u53ca\u5176\u6392\u6cc4\u7269\u548c\u7ec6\u83cc\u901a\u5e38\u4f1a\u4f7f\u514d\u75ab\u7cfb\u7edf\u8fdc\u79bbTH2\u514d\u75ab\u53cd\u5e94\u548c\u8fc7\u654f\u3002\u8fd9\u79cd\u60f3\u6cd5\u88ab\u79f0\u4e3a\u536b\u751f\u5047\u8bf4\uff0c\u8be5\u5047\u8bf4\u8ba4\u4e3a\uff0c\u5728\u53d1\u8fbe\u56fd\u5bb6\u8fc7\u654f\u53d1\u75c5\u7387\u7684\u589e\u52a0\u662f\u7531\u4e8e\u5728\u65e9\u671f\u751f\u6d3b\u4e2d\u8f83\u5c11\u63a5\u89e6\u5fae\u751f\u7269\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u536b\u751f\u5047\u8bf4\u542f\u53d1\u4e86\u4e00\u4e9b\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8fd9\u4e9b\u8bd5\u9a8c\u8ba9\u513f\u7ae5\u63a5\u89e6\u65e0\u5bb3\u7684\u5fae\u751f\u7269\uff0c\u7814\u7a76\u4e86\u65e0\u5bb3\u5fae\u751f\u7269\u5bf9\u8fc7\u654f\u7684\u5f71\u54cd\u3002\u8fd9\u4e9b\u7814\u7a76\u5305\u62ec\u5bf9\u725b\u5976\u4e2d\u6240\u8c13\u7684\u201c\u76ca\u751f\u83cc\u201d\u7ec6\u83cc\u548c\u6d3b\u75ab\u82d7\u7684\u7814\u7a76\u3002\u4f46\u8fd9\u4e9b\u65b9\u6cd5\u5728\u9884\u9632\u8fc7\u654f\u65b9\u9762\u90fd\u6ca1\u6709\u660e\u663e\u7684\u597d\u5904\u3002\u73b0\u5728\u6211\u4eec\u77e5\u9053\u536b\u751f\u5047\u8bf4\u8fc7\u4e8e\u7b80\u5355\u5316\u4e86\u3002\u4f8b\u5982\uff0c\u4e00\u4e9b\u8815\u866b\u7684\u611f\u67d3\uff0c\u5982\u8840\u5438\u866b(\u7b2c22\u7ae0<\/span>)\uff0c\u8fd9\u4e9b\u8815\u866b\u5f15\u8d77TH2\u514d\u75ab\u53cd\u5e94\u5374\u964d\u4f4e\u4e86\u8fc7\u654f\u7684\u98ce\u9669\u3002\u5728\u4e16\u754c\u4e0a\u63a5\u89e6\u4f20\u67d3\u6027\u5fae\u751f\u7269\u4ecd\u7136\u975e\u5e38\u666e\u904d\u7684\u5730\u533a\uff0c\u4f8b\u5982\u5728\u5357\u7f8e\u6d32\u7684\u4e00\u4e9b\u5730\u533a\uff0c\u8fc7\u654f\u53d8\u5f97\u8d8a\u6765\u8d8a\u666e\u904d\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u76ee\u524d\u7684\u8bf4\u6cd5\u662f\uff0c\u8fc7\u654f\u7684\u53d1\u5c55\u98ce\u9669\u53d6\u51b3\u4e8e\u66b4\u9732\u7684\u786e\u5207\u65f6\u95f4\u548c\u4e2a\u4eba\u7684\u57fa\u56e0\u578b\u3002\u6b64\u5916\uff0c\u5176\u4ed6\u73af\u5883\u53d8\u5316\u53ef\u80fd\u4e5f\u5bfc\u81f4\u4e86\u8fc7\u654f\u53d1\u75c5\u7387\u7684\u589e\u52a0\uff0c\u6bd4\u5982\u67d0\u4e9b\u7c7b\u578b\u7684\u7a7a\u6c14\u6c61\u67d3\u548c\u98df\u7528\u8fc7\u91cf\u7684\u98df\u7269\u5bfc\u81f4\u7684\u80a5\u80d6\u3002\u4f17\u6240\u5468\u77e5\uff0c\u80a5\u80d6\u548c\u7a7a\u6c14\u6c61\u67d3\u90fd\u4f1a\u5f15\u53d1\u708e\u75c7\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u968f\u7740\u8868\u89c2\u9057\u4f20\u5b66\u77e5\u8bc6\u7684\u63d0\u5347\uff0c\u4eba\u4eec\u8d8a\u6765\u8d8a\u6e05\u695a\u5730\u8ba4\u8bc6\u5230\uff0c\u5bf9\u73af\u5883\u56e0\u7d20\u7684\u7814\u7a76\u53ef\u4ee5\u5e2e\u52a9\u63a2\u7d22\u9884\u9632\u8fc7\u654f\u7684\u5e72\u9884\u63aa\u65bd\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u8fc7\u654f\u65e9\u671f\u7684\u5a92\u4ecb\u56e0\u5b50<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5f53\u4e0eFc\u03b5RI\u7ed3\u5408\u7684IgE\u88ab\u8fc7\u654f\u539f\u4ea4\u8054\u65f6\uff0c\u80a5\u5927\u7ec6\u80de\u91ca\u653e\u7684\u4ecb\u8d28\u4f1a\u5f15\u8d77\u8fc7\u654f\u7684\u65e9\u671f\u53cd\u5e94\u3002\u82e5\u8fc7\u654f\u539f\u80fd\u4ece\u4efb\u4f55\u9014\u5f84\u8fdb\u5165\u4eba\u4f53\u53d1\u751f\u8fc7\u654f\u6027\u53cd\u5e94\uff0c\u90a3\u4e48\u8fd9\u5c31\u662f\u6700\u4e25\u91cd\u7684\u8fc7\u654f\u7c7b\u578b\u3002\u5728\u8fc7\u654f\u53cd\u5e94\u671f\u95f4\uff0c\u80a5\u5927\u7ec6\u80de\u901a\u8fc7\u73af\u6c27\u5408\u9176\u548c\u8102\u6c27\u5408\u9176\u9014\u5f84\u5feb\u901f\u5408\u6210\u524d\u5217\u817a\u7d20\u548c\u767d\u4e09\u70ef(\u7b2c22\u7ae0<\/span>)\u3002\u8fd9\u4e9b\u4ecb\u8d28\u5f15\u8d77\u8840\u7ba1\u8212\u5f20\u548c\u8840\u7ba1\u901a\u900f\u6027\u7684\u589e\u52a0\u3002\u6b64\u5916\uff0c\u8fc7\u654f\u53cd\u5e94\u7684\u7279\u5f81\u662f\u8840\u7ba1\u5f20\u529b\u4e0b\u964d\uff1b\u5927\u91cf\u7684\u80a5\u5927\u7ec6\u80de\u6d3b\u5316\u4f7f\u8840\u538b\u6025\u5267\u4e0b\u964d\uff1b\u76ae\u80a4\u4e2d\u7684\u80a5\u5927\u7ec6\u80de\u91ca\u653e\u7684\u7ec4\u80fa\u53ef\u5bfc\u81f4\u80bf\u80c0\u548c\u4f53\u6db2\u8f6c\u79fb\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u5176\u4ed6\u5f62\u5f0f\u7684\u8fc7\u654f\u4e2d\uff0c\u4f1a\u53d1\u751f\u66f4\u591a\u7684\u5c40\u90e8\u53d8\u5316\uff0c\u8fd9\u4e9b\u53d8\u5316\u4ec5\u9650\u4e8e\u8fc7\u654f\u539f\u8fdb\u5165\u7684\u90e8\u4f4d\u3002\u4f8b\u5982\uff0c\u5728\u53d8\u5e94\u6027\u9f3b\u708e\u4e2d\uff0c\u5438\u5165\u7684\u8fc7\u654f\u539f\u4f1a\u523a\u6fc0\u9f3b\u9ecf\u819c\u4e2d\u7684\u80a5\u5927\u7ec6\u80de\u3002\u968f\u540e\u4f7f\u8840\u7ba1\u6269\u5f20\u548c\u9f3b\u5b50\u6c34\u80bf\uff0c\u5bfc\u81f4\u9f3b\u585e\u548c\u6253\u55b7\u568f\u3002\u5176\u4e2d\uff0c\u767d\u4e09\u70ef(\u7b2c22\u7ae0<\/span>)\u589e\u52a0\u7c98\u6db2\u5206\u6ccc\uff0c\u5bfc\u81f4\u8fc7\u654f\u6027\u9f3b\u708e\u7684\u5206\u6ccc\u6027\u7279\u5f81\u3002\u5728\u54ee\u5598\u4e2d\uff0c\u652f\u6c14\u7ba1\u7c98\u6db2\u5206\u6ccc\u589e\u52a0\u4f1a\u4f7f\u6c14\u6d41\u963b\u585e\u3002\u7136\u800c\uff0c\u5728\u80ba\u90e8\uff0c\u767d\u4e09\u70ef\u4f1a\u5f15\u8d77\u5e73\u6ed1\u808c\u6536\u7f29\uff0c\u8fd9\u662f\u9020\u6210\u6c14\u6d41\u963b\u585e\u7684\u4e3b\u8981\u539f\u56e0<\/span>(Fig. 27.5<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n

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Fig 27.5 <\/span>\u8fc7\u654f\u75c7\u65e9\u671f\u9636\u6bb5\u7684\u4ecb\u8d28\u6839\u636e\u9776\u7ec4\u7ec7\u7684\u4e0d\u540c\u4ea7\u751f\u4e0d\u540c\u7684\u540e\u679c\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u80a5\u5927\u7ec6\u80de\u8131\u9897\u7c92\u4e5f\u4f1a\u91ca\u653e\u9176\u3002\u8fd9\u4e9b\u9176\u53ef\u6fc0\u6d3b\u4fe1\u4f7f\u5206\u5b50\uff0c\u5982\u8865\u4f53\u548c\u6fc0\u80bd\u3002\u80a5\u5927\u7ec6\u80de\u80f0\u86cb\u767d\u9176\u5728\u8bca\u65ad\u8fc7\u654f\u53cd\u5e94\u7684\u4e34\u5e8a\u533b\u5b66\u4e2d\u6709\u7279\u6b8a\u4f5c\u7528(Box 27.2; Box 22.1<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e0a\u8ff0\u6240\u6709\u7684\u5f71\u54cd\u4f1a\u5728\u63a5\u89e6\u8fc7\u654f\u539f\u7684\u51e0\u5206\u949f\u5185\u53d1\u751f\u3002\u5018\u82e5\u6301\u7eed\u63a5\u89e6\u8fc7\u654f\u539f\uff0c\u75c7\u72b6\u4f1a\u6301\u7eed\u5b58\u5728\u3002\u5373\u4f7f\u60a3\u8005\u80fd\u591f\u907f\u5f00\u8fc7\u654f\u539f\uff0c\u4e5f\u53ef\u80fd\u4f1a\u6709\u665a\u671f\u53cd\u5e94\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n

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\u8fc7\u654f\u540e\u671f\u7684\u4ecb\u8d28<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
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\n

\u2160\u578b\u8d85\u654f\u53cd\u5e94\u7684\u7279\u5f81\u4e00\u822c\u662f\u63a5\u89e6\u8fc7\u654f\u539f\u540e\u7acb\u5373\u51fa\u73b0\u75c7\u72b6\u3002\u4f8b\u5982\uff0c\u5bf9\u732b\u8fc7\u654f\u7684\u54ee\u5598\u60a3\u8005\u4f1a\u5728\u63a5\u89e6\u732b\u51e0\u79d2\u949f\u540e\u51fa\u73b0\u6c14\u9053\u963b\u585e\u7684\u75c7\u72b6\uff0c\u7279\u5f81\u662f\u5598\u606f\u3002\u968f\u7740\u2160\u578b\u8d85\u654f\u53cd\u5e94\u7684\u51cf\u5f31\uff0c\u75c7\u72b6\u4e00\u5c0f\u65f6\u5de6\u53f3\u5c31\u4f1a\u5f97\u5230\u6539\u5584\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u6025\u6027\u53d1\u4f5c\u51e0\u5c0f\u65f6\u540e\uff0c\u652f\u6c14\u7ba1\u7684\u6c14\u6d41\u53ef\u80fd\u518d\u6b21\u6076\u5316\uff0c\u767d\u7ec6\u80de\uff08\u7279\u522b\u662f\u55dc\u9178\u6027\u7c92\u7ec6\u80de\uff09\u7531\u4e8e\u8d8b\u5316\u56e0\u5b50\u7684\u4f5c\u7528\u800c\u8fc1\u79fb\u5230\u652f\u6c14\u7ba1\u3002\u8fc7\u654f\u540e\u671f\u9636\u6bb5\u53ef\u80fd\u4f1a\u6301\u7eed\u51e0\u4e2a\u5c0f\u65f6(Fig <\/span>27.6<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u4e00\u4e9b\u4e2a\u4f53\u4e2d\uff0c\u652f\u6c14\u7ba1\u58c1\u4e2d\u7684TH2\u7ec6\u80de\u4f1a\u5206\u6cccIL-4\u548c\u8bf1\u5bfc\u6027\u8d8b\u5316\u56e0\u5b50\u7b49\u7ec6\u80de\u56e0\u5b50\uff0c\u8fdb\u800c\u5bfc\u81f4\u547c\u5438\u9053\u51fa\u73b0\u6162\u6027\u8fc7\u654f\u6027\u708e\u75c7\u3002\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u91ca\u653e\u7684\u4ecb\u8d28\u5305\u62ec\u8fc7\u6c27\u5316\u7269\u9176\u3001\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u4e3b\u8981\u78b1\u6027\u86cb\u767d\u548c\u9633\u79bb\u5b50\u86cb\u767d\uff0c\u5b83\u4eec\u90fd\u4f1a\u5bf9\u652f\u6c14\u7ba1\u7ec4\u7ec7\u9020\u6210\u76f4\u63a5\u635f\u4f24\u3002\u7531\u4e8e\u6162\u6027\u8fc7\u654f\u6027\u708e\u75c7\u7684\u5f71\u54cd\uff0c\u5bfc\u81f4\u652f\u6c14\u7ba1\u5e73\u6ed1\u808c\u80a5\u5927\u548c\u7c98\u6db2\u5206\u6ccc\u589e\u52a0\uff1b\u6c14\u6d41\u6301\u7eed\u51cf\u5c11(\u800c\u975e\u95f4\u6b47\u6027\u51cf\u5c11)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/section>\n<\/section>\n
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<\/p>\n<\/section>\n<\/section>\n

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Fig 27.6 <\/span>\u8fc7\u654f\u7684\u836f\u7269\u6cbb\u7597<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n

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\u6cbb\u7597<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u8fc7\u654f\u4f1a\u4ea7\u751f\u4e00\u7cfb\u5217\u75c7\u72b6\uff0c\u4ece\u8f7b\u5fae\u7684\u75c7\u72b6\uff08\u4f8b\u5982\u9f3b\u708e\u4e2d\u7684\u9f3b\u585e\uff09\u5230\u5371\u53ca\u751f\u547d\u7684\u75c7\u72b6\uff08\u4f8b\u5982\u4e25\u91cd\u7684\u54ee\u5598\u6216\u8fc7\u654f\u53cd\u5e94\uff09\u3002\u8fc7\u654f\u7684\u6cbb\u7597\u662f\u6839\u636e\u60a3\u8005\u7684\u60c5\u51b5\u548c\u75c7\u72b6\u800c\u4e2a\u6027\u5316\u5236\u5b9a\u7684\u3002\u6cbb\u7597\u8fc7\u654f\u7684\u4e00\u822c\u63aa\u65bd\u5305\u62ec\u8bc6\u522b\u548c\u907f\u514d\u53ef\u80fd\u7684\u8fc7\u654f\u539f\uff0c\u5176\u4ed6\u6cbb\u7597\u5305\u62ec\u4f7f\u7528\u836f\u7269\u6216\u8131\u654f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u836f\u7269\u6cbb\u7597<\/strong><\/p>\n<\/section>\n

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\u4e00\u4e9b\u836f\u7269\u80fd\u963b\u65ad\u4ecb\u8d28\u91ca\u653e\u7684\u7ec8\u672b\u6548\u5e94\u3002\u4f8b\u5982\uff0c\u03b22-\u80be\u4e0a\u817a\u7d20\u80fd\u6fc0\u52a8\u5242\uff0c\u5982\u6c99\u4e01\u80fa\u9187\uff0c\u4e3b\u8981\u901a\u8fc7\u9632\u6b62\u54ee\u5598\u60a3\u8005\u7684\u652f\u6c14\u7ba1\u5e73\u6ed1\u808c\u6536\u7f29\u6765\u53d1\u6325\u4f5c\u7528(\u89c1Fig 27.6<\/span>)\u3002\u80be\u4e0a\u817a\u7d20\u662f\u4e00\u79cd\u91cd\u8981\u7684\u836f\u7269\uff0c\u5728\u8fc7\u654f\u53cd\u5e94\u4e2d\u53ef\u4ee5\u633d\u6551\u751f\u547d\u3002\u56e0\u4e3a\u5728\u8fc7\u654f\u53cd\u5e94\u4e2d\uff0c\u7531\u4e8e\u8840\u7ba1\u901a\u900f\u6027\u589e\u52a0\u65f6\uff0c\u6db2\u4f53\u4f1a\u6d41\u51fa\u8840\u7ba1\uff0c\u8fdb\u5165\u7ec4\u7ec7\uff0c\u8840\u538b\u4f1a\u6025\u5267\u4e0b\u964d\u3002\u800c\u80be\u4e0a\u817a\u7d20\u80fd\u591f\u523a\u6fc0\u03b1\u548c\u03b2\u80be\u4e0a\u817a\u7d20\u80fd\u53d7\u4f53\uff0c\u964d\u4f4e\u8840\u7ba1\u901a\u900f\u6027\uff0c\u5347\u9ad8\u8840\u538b\uff0c\u9006\u8f6c\u6c14\u9053\u963b\u585e\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u6297\u7ec4\u80fa\u836f\u7269\u80fd\u963b\u65ad\u7279\u5b9a\u7684\u7ec4\u80fa\u53d7\u4f53\uff0c\u5e76\u5728\u5f71\u54cd\u76ae\u80a4\u3001\u9f3b\u5b50\u548c\u7c98\u819c\u7684\u8fc7\u654f\u75c7\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u3002\u7531\u4e8e\u7ec4\u80fa\u4e0d\u662f\u80ba\u5185\u80a5\u5927\u7ec6\u80de\u91ca\u653e\u7684\u91cd\u8981\u8fc7\u654f\u4ecb\u8d28\u3002\u56e0\u6b64\uff0c\u6297\u7ec4\u80fa\u836f\u7269\u5728\u6cbb\u7597\u8fc7\u654f\u53cd\u5e94\u65b9\u9762\u7684\u4f5c\u7528\u6bd4\u80be\u4e0a\u817a\u7d20\u6162\u5f97\u591a\uff0c\u5bf9\u54ee\u5598\u4e5f\u4e0d\u662f\u5f88\u6709\u7528\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u7279\u5f02\u6027\u53d7\u4f53\u62ee\u6297\u5242\u53ef\u963b\u65ad\u767d\u4e09\u70ef\u7684\u4f5c\u7528\u3002\u4f8b\u5982\uff0c\u5b5f\u9c81\u53f8\u7279(Montelukast)\u53ef\u4ee5\u51cf\u5c11\u54ee\u5598\u60a3\u8005\u7684\u6c14\u9053\u708e\u75c7\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u76ae\u8d28\u7c7b\u56fa\u9187\u88ab\u5e7f\u6cdb\u7528\u4e8e\u9884\u9632\u8fc7\u654f\u60a3\u8005\u7684\u75c7\u72b6\u3002\u8fd9\u4e9b\u5c06\u5728\u7b2c31\u7ae0<\/span>\u8be6\u7ec6\u8ba8\u8bba\u3002\u76ae\u8d28\u7c7b\u56fa\u9187\u53ef\u4ee5\u9884\u9632\u901f\u53d1\u578b\u8fc7\u654f\u53cd\u5e94\u3001\u665a\u671f\u8fc7\u654f\u53cd\u5e94\u548c\u6162\u6027\u8fc7\u654f\u6027\u708e\u75c7\u3002\u4e3a\u907f\u514d\u526f\u4f5c\u7528\uff0c\u76ae\u8d28\u7c7b\u56fa\u9187\u901a\u5e38\u5728\u8fc7\u654f\u65f6\u5c40\u90e8\u7ed9\u836f\uff1b\u4f8b\u5982\uff0c\u5438\u5165\u7c7b\u56fa\u9187\u7528\u4e8e\u54ee\u5598\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u8272\u7518\u9178\u94a0\u5728\u9884\u9632\u8fc7\u654f\u53d1\u4f5c\u65b9\u9762\u6709\u4e00\u5b9a\u6548\u679c\u3002\u5b83\u88ab\u8ba4\u4e3a\u662f\u901a\u8fc7\u7a33\u5b9a\u80a5\u5927\u7ec6\u80de\u548c\u51cf\u5c11\u8131\u9897\u7c92\u6765\u53d1\u6325\u4f5c\u7528\u7684\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5176\u4ed6\u6b63\u5728\u5f00\u53d1\u4e2d\u7684\u836f\u7269\u65e8\u5728\u963b\u65adTH2\u7ec6\u80de\u56e0\u5b50\u9014\u5f84\u6216\u963b\u6b62IgE\u4e0eFc\u03b5R\u7ed3\u5408\u3002\u4eba\u4eec\u8fd8\u91c7\u53d6\u4e86\u4e00\u4e9b\u6709\u8da3\u7684\u65b9\u6cd5\u6765\u964d\u4f4e\u73af\u5883\u8fc7\u654f\u539f\u7684\u8fc7\u654f\u539f\u6027\u3002\u4f8b\u5982\uff0c\u4e00\u5bb6\u751f\u7269\u6280\u672f\u516c\u53f8\u5df2\u7ecf\u57f9\u80b2\u51fa\u4e0d\u4ea7\u751f\u732b\u8fc7\u654f\u539fFelD1\u7684\u8f6c\u57fa\u56e0\u732b\u3002\u8fd9\u4e9b\u732b\u4e0d\u4f1a\u5f15\u8d77\u8fc7\u654f\u60a3\u8005\u7684\u8fc7\u654f\u75c7\u72b6\uff0c\u4f46\u6bcf\u53ea\u732b\u8d85\u8fc71000\u7f8e\u5143\uff0c\u8fd9\u79cd\u89e3\u51b3\u65b9\u6848\u53ef\u80fd\u4e0d\u592a\u53d7\u5927\u4f17\u6b22\u8fce\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u8fc7\u654f\u539f\u514d\u75ab\u7597\u6cd5<\/strong><\/p>\n<\/section>\n

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\u8fc7\u654f\u539f\u514d\u75ab\u7597\u6cd5\u6216\u8131\u654f(\u8fc7\u654f\u9488)\u76ee\u524d\u662f\u4e00\u9879\u6210\u719f\u7684\u6280\u672f\uff0c\u65e8\u5728\u6539\u5584\u7279\u5b9a\u8fc7\u654f\u539f\u5f15\u8d77\u7684\u8fc7\u654f\u75c7\u72b6\u3002\u5b83\u5728\u75c7\u72b6\u4ec5\u6d89\u53ca\u5355\u4e00\u8fc7\u654f\u539f\u65f6\u6548\u679c\u6700\u597d\u3002\u901a\u5e38\u88ab\u5e94\u7528\u4e8e\u6606\u866b\u53ee\u54ac\u5f15\u8d77\u7684\u8fc7\u654f\u53cd\u5e94\uff0c\u8fd8\u53ef\u51cf\u8f7b\u7531\u4e8e\u8349\u82b1\u7c89\u8fc7\u654f\u5f15\u8d77\u7684\u5e72\u8349\u70ed\u7684\u75c7\u72b6\u3002\u867d\u7136\u6cbb\u7597\u5f00\u59cb\u65f6\u6ce8\u5c04\u7684\u8fc7\u654f\u539f\u5242\u91cf\u975e\u5e38\u5c0f\uff0c\u4f46\u4f9d\u7136\u5b58\u5728\u5f15\u53d1\u5168\u8eab\u6027\u8fc7\u654f\u53cd\u5e94\u7684\u98ce\u9669\u3002\u56e0\u6b64\uff0c\u6709\u7ecf\u9a8c\u7684\u5de5\u4f5c\u4eba\u5458\u5fc5\u987b\u4f7f\u7528\u590d\u82cf\u8bbe\u5907\u8fdb\u884c\u8131\u654f\u6cbb\u7597\u3002\u968f\u7740\u65f6\u95f4\u7684\u63a8\u79fb\uff0c\u7ed9\u60a3\u8005\u6ce8\u5c04\u8d8a\u6765\u8d8a\u591a\u7684\u8fc7\u654f\u539f\uff0c\u76f4\u5230\u7ed9\u4e88\u8db3\u591f\u7684\u8fc7\u654f\u539f\u6765\u6291\u5236\u8fc7\u654f\u53cd\u5e94\u3002\u53e6\u4e00\u79cd\u6cbb\u7597\u65b9\u6cd5\u662f\u820c\u4e0b\u514d\u75ab\u7597\u6cd5\uff0c\u7528\u4e8e\u6cbb\u7597\u82b1\u7c89\u75c7\u3002\u65b9\u6cd5\u662f\u7ed9\u4e88\u5c0f\u5242\u91cf\u7684\u7eaf\u5316\u8349\u82b1\u7c89\u4e8e\u60a3\u8005\u7684\u820c\u4e0b\u51e0\u4e2a\u6708\uff0c\u53ef\u51cf\u8f7b\u8fc7\u654f\u75c7\u72b6\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\n

\u7b2c18\u7ae0<\/span>\u89e3\u91ca\u4e86\u5927\u5242\u91cf\u7684\u8702\u6bd2\u8fc7\u654f\u539f\u662f\u5982\u4f55\u5728\u7ecf\u5e38\u88ab\u8707\u7684\u4eba\u8eab\u4e0a\u8bf1\u5bfcTregs\u7684\u3002\u514d\u75ab\u7597\u6cd5\u6ce8\u5c04\u7684\u4f5c\u7528\u65b9\u5f0f\u4e5f\u662f\u76f8\u540c\u7684\u3002\u968f\u7740\u5242\u91cf\u7684\u589e\u52a0\u8bf1\u5bfcTregs\u3002\u8fd9\u4e9bTregs\u5206\u6cccIL-10\uff0c\u4ece\u800c\u964d\u4f4eTH2\u7ec6\u80de\u7684\u6d3b\u6027\uff0c\u51cf\u5c11IgE\u7684\u5206\u6ccc(Fig 27.7<\/span>)\u3002\u540c\u65f6\uff0c\u7279\u5f02\u6027IgG\u5206\u6ccc\u589e\u52a0\u3002\u53ea\u6709\u5f53\u9ad8\u5242\u91cf\u7684\u8fc7\u654f\u539f\u88ab\u8f93\u5165\u65f6\u624d\u80fd\u5b9e\u73b0\u8fd9\u4e9b\u8c03\u8282\u4f5c\u7528\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/section>\n<\/section>\n
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\n


<\/p>\n<\/section>\n<\/section>\n

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Fig 27.7<\/span> \u514d\u75ab\u7597\u6cd5\u8bf1\u5bfc\u8c03\u8282\u6027T\u7ec6\u80de<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u820c\u4e0b\u514d\u75ab\u7597\u6cd5\u8bf1\u5bfc\u8c03\u8282\u6027T\u7ec6\u80de\u7684\u65b9\u5f0f\u7565\u6709\u4e0d\u540c\u3002\u540c\u6837\u5242\u91cf\u7684\u82b1\u7c89\u653e\u5728\u82b1\u7c89\u8fc7\u654f\u7684\u4eba\u7684\u9f3b\u5b50\u91cc\u4f1a\u5f15\u8d77\u4e25\u91cd\u7684\u75c7\u72b6\u3002\u4f46\u662f\u56e0\u4e3a\u53e3\u8154\u4e2d\u542b\u6709\u5f88\u5c11\u91cf\u7684\u80a5\u5927\u7ec6\u80de\uff0c\u6240\u4ee5\u53e3\u670d\u4e00\u5b9a\u5242\u91cf\u7684\u8349\u82b1\u7c89\u4e0d\u4f1a\u5f15\u8d77\u4efb\u4f55\u8fc7\u654f\u75c7\u72b6\u3002\u53e3\u8154\u548c\u76f8\u5173\u6dcb\u5df4\u7ed3\u4e2d\u7684APCs\u503e\u5411\u4e8e\u8bf1\u5bfcTregs\u3002\u8fd9\u4e9bTregs\u5206\u6cccIL-10\uff0c\u5bfc\u81f4IgE\u751f\u6210\u51cf\u5c11\uff1b\u56e0\u6b64\uff0c\u820c\u4e0b\u63a5\u89e6\u8349\u82b1\u7c89\u6700\u7ec8\u4f1a\u51cf\u5f31\u8fc7\u654f\u75c7\u72b6\uff0c\u5373\u4f7f\u540e\u7eed\u82b1\u7c89\u662f\u5230\u8fbe\u9f3b\u5b50\u7684\u60c5\u51b5\u3002 <\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u8fd9\u4e24\u79cd\u7c7b\u578b\u7684\u6cbb\u7597\u8bf4\u660e\u4e86\u6539\u53d8\u5242\u91cf(\u5728\u6ce8\u5c04\u8131\u654f\u7684\u60c5\u51b5\u4e0b)\u6216\u7ed9\u836f\u9014\u5f84(\u5728\u820c\u4e0b\u8131\u654f\u7684\u60c5\u51b5\u4e0b)\u65f6\u662f\u5982\u4f55\u5f71\u54cd\u514d\u75ab\u7ed3\u679c\u7684\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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BOX 27.1 <\/span>\u4e73\u80f6\u8fc7\u654f<\/span><\/p>\n<\/section>\n<\/section>\n

\n
\n
<\/svg><\/section>\n<\/section>\n
\n
<\/svg><\/section>\n<\/section>\n<\/section>\n
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\n

\u4e00\u540d25\u5c81\u7684\u5973\u6027\u5728\u7259\u79d1\u624b\u672f\u5f00\u59cb\u51e0\u5206\u949f\u540e\u51fa\u73b0\u820c\u5934\u548c\u5634\u5507\u80bf\u80c0\uff0c\u5728\u5403\u5b8c\u6c34\u679c\u6c99\u62c9\u540e\uff0c\u6709\u51e0\u6b21\u4e5f\u6709\u7c7b\u4f3c\u7684\u80bf\u80c0\u3002\u5979\u60a3\u6709\u54ee\u5598\uff0c\u5979\u7684\u6bcd\u4eb2\u548c\u54e5\u54e5\u90fd\u6709\u8fc7\u654f\u75c7\u3002\u7528\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u6765\u8c03\u67e5\u5bf9\u4e73\u80f6\u548c\u6c34\u679c\u8fc7\u654f\u7684\u53ef\u80fd\u6027\u3002\u572810\u5206\u949f\u5185\u5c31\u53ef\u4ee5\u8bfb\u53d6\u6d4b\u8bd5\u7ed3\u679c\uff0c\u5e76\u786e\u5b9a\u5979\u5bf9\u4e73\u80f6\u3001\u9999\u8549\u3001\u9cc4\u68a8\u548c\u7315\u7334\u6843\u8fc7\u654f(Fig 27.8<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n

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<\/section>\n<\/section>\n
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Fig 27.8 <\/span>\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u3002\u4e3a\u4e86\u63d0\u4f9b\u5bf9\u7167\uff0c\u5728\u4f4d\u7f6e1\u6d82\u62b9\u7ec4\u80fa\u6eb6\u6db2\uff0c\u5728\u4f4d\u7f6e2\u6d82\u62b9\u751f\u7406\u76d0\u6c34<\/p>\n


<\/p>\n<\/section>\n

\n

\u523a\u7a7f\u771f\u76ae\uff0c10\u5206\u949f\u540e\u7ec4\u80fa\u5904\u51fa\u73b0\u9633\u6027\u53cd\u5e94\uff1b\u5982\u679c\u60a3\u8005\u6700\u8fd1\u670d\u7528\u4e86\u6297\u7ec4\u80fa\u836f\u7269\uff0c\u8fd9\u79cd\u60c5\u51b5\u5c06\u4e0d\u4f1a\u53d1\u751f\u3002\u751f\u7406\u76d0\u6c34\u5904\u6ca1\u6709\u4efb\u4f55\u53cd\u5e94\uff0c\u8fd9\u8bc1\u5b9e\u4e86\u60a3\u8005\u7684\u76ae\u80a4\u4e0d\u662f\u5bf9\u521b\u4f24\u6709\u53cd\u5e94\u3002\u57283\u53f7\u548c4\u53f7\u4f4d\u7f6e\u4f7f\u7528\u4e86\u5c4b\u5c18\u87a8\u7caa\u4fbf\u548c\u6811\u6728\u82b1\u7c89\uff0c\u60a3\u8005\u5bf9\u8fd9\u4e9b\u90fd\u6ca1\u6709\u53cd\u5e94\u3002\u7b2c5\u30016\u30017\u548c8\u53f7\u5219\u5206\u522b\u662f\u9cc4\u68a8\u3001\u9999\u8549\u3001\u7315\u7334\u6843\u548c\u4e73\u80f6\u60ac\u6d6e\u6db2\u7684\u63d0\u53d6\u7269\u3002\u60a3\u8005\u5bf9\u8fd9\u56db\u79cd\u836f\u7269\u90fd\u6709\u53cd\u5e94\uff0c\u5176\u4e2d\u5bf9\u7315\u7334\u6843\u548c\u9999\u8549\u7684\u53cd\u5e94\u6700\u5f3a\u3002<\/span><\/p>\n<\/section>\n

\n

\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u662f\u8fc7\u654f\u8bd5\u9a8c\u7684\u9996\u9009\u65b9\u6cd5\u3002\u5f53\u901a\u8fc7\u7a7f\u523a\u5f15\u5165\u7684\u6297\u539f\u4e0e\u80a5\u5927\u7ec6\u80deFc\u03b5RI\u4e0a\u7684\u514d\u75ab\u7403\u86cb\u767d (IgE)\u4ea4\u8054\u65f6\uff0c\u7ec4\u80fa\u7684\u5feb\u901f\u91ca\u653e\u5bfc\u81f4\u5c40\u90e8\u7206\u53d1\u548c\u98ce\u56e2\u53cd\u5e94\u3002\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u53ef\u4ee5\u7acb\u5373\u5f97\u51fa\u7ed3\u679c\uff0c\u800c\u4e14\u6bd4\u8840\u6db2\u6837\u672c\u7684\u7279\u5f02\u6027IgE\u68c0\u6d4b\u66f4\u4fbf\u5b9c\u3001\u66f4\u654f\u611f\u3002\u5f53\u60a3\u8005\u670d\u7528\u6297\u7ec4\u80fa\u836f\u65f6\uff0c\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u5c31\u4e0d\u53ef\u884c\u4e86\uff1b\u5728\u8fd9\u4e9b\u60c5\u51b5\u4e0b\uff0c\u6d4b\u91cf\u7279\u5f02\u6027IgE\u6c34\u5e73\u662f\u6700\u6709\u7528\u7684\u3002\u76f8\u5e94\u7684\u56fe(Fig 27.9<\/span>)\u663e\u793a\u4e86\u76ae\u80a4\u80bf\u80c0\u662f\u5982\u4f55\u8fc5\u901f\u53d1\u5c55\u7684\u3002<\/span><\/p>\n<\/section>\n

\n
<\/section>\n<\/section>\n
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Fig 27.9<\/span> \u8fc7\u654f\u539f\u523a\u7a7f\u76ae\u80a410\u5206\u949f\u540e\uff0c\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u5448\u9633\u6027\u3002<\/span><\/span><\/p>\n


<\/span><\/span><\/p>\n<\/section>\n

\n

\u6a61\u80f6\u3001\u9999\u8549\u3001\u9cc4\u68a8\u548c\u7315\u7334\u6843\u690d\u7269\u5728\u690d\u7269\u5b66\u4e0a\u662f\u76f8\u5173\u7684\uff0c\u5e76\u4e14\u542b\u6709\u975e\u5e38\u76f8\u4f3c\u7684\u53ef\u4ee4\u60a3\u8005\u8fc7\u654f\u7684\u86cb\u767d\u8d28\u3002\u5982\u679c\u5979\u518d\u6b21\u63a5\u89e6\u8fd9\u4e9b\u8fc7\u654f\u539f\uff0c\u5979\u53ef\u80fd\u4f1a\u6709\u66f4\u4e25\u91cd\u7684\u53cd\u5e94\u3002\u56e0\u6b64\u544a\u8beb\u75c5\u4eba\u662f\u5f88\u91cd\u8981\u7684\uff0c\u9700\u8981\u786e\u4fdd\u5979\u77e5\u9053\u5982\u4f55\u5728\u672a\u6765\u907f\u514d\u4e0e\u76f8\u5173\u7684\u6c34\u679c\u548c\u4e73\u80f6\u63a5\u89e6\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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BOX 27.2<\/span>\u82b1\u751f\u8fc7\u654f<\/span><\/p>\n<\/section>\n<\/section>\n

\n
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<\/svg><\/section>\n<\/section>\n
\n
<\/svg><\/section>\n<\/section>\n<\/section>\n
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\u4e00\u540d4\u5c81\u7537\u5b69\u56e0\u9762\u90e8\u80bf\u80c0\u3001\u5168\u8eab\u7619\u75d2\u548c\u55dc\u7761\u88ab\u9001\u5f80\u6025\u8bca\u79d1\u3002\u8fd9\u4e9b\u75c7\u72b6\u662f\u5728\u5403\u4e0b\u4e00\u5757\u5de7\u514b\u529b\u68d2\u51e0\u5206\u949f\u540e\u51fa\u73b0\u7684\u3002\u6025\u8bca\u79d1\u533b\u751f\u53d1\u73b0\u4ed6\u6709\u9762\u90e8\u8840\u7ba1\u6027\u6c34\u80bf(Fig 27.10<\/span>)\u548c\u8368\u9ebb\u75b9(Fig 27.11<\/span>)\uff0c\u4e14\u8840\u538b\u504f\u4f4e\u3002\u56e0\u6b64\u4ed6\u63a5\u53d7\u4e86150\u03bcg\u80be\u4e0a\u817a\u7d20(\u513f\u79d1\u5242\u91cf)\u7684\u808c\u8089\u6ce8\u5c04\uff0c\u51e0\u5206\u949f\u540e\u4ed6\u5c31\u5f00\u59cb\u6062\u590d\u4e86\u3002\u4ed6\u7684\u6bcd\u4eb2\u89e3\u91ca\u8bf4\uff0c\u4ed6\u8fc7\u53bb\u5bf9\u575a\u679c\u6709\u8f7b\u5fae\u53cd\u5e94\uff0c\u4f1a\u5f15\u8d77\u5634\u5507\u80bf\u80c0\u3002\u5e76\u4e14\u8fd9\u4e2a\u7537\u5b69\u4e5f\u6709\u6e7f\u75b9(Fig 27.12<\/span>)\uff0c\u5f53\u4ed6\u5403\u82b1\u751f\u65f6\u6e7f\u75b9\u5c31\u4f1a\u53d1\u4f5c\u3002\u56e0\u6b64\uff0c\u5979\u7684\u6bcd\u4eb2\u5f97\u51fa\u4ed6\u53ef\u80fd\u5bf9\u575a\u679c\u8fc7\u654f\u7684\u7ed3\u8bba\uff0c\u5e76\u5c06\u575a\u679c\u4ece\u5bb6\u91cc\u6e05\u9664\u3002\u60a3\u8005\u4ece\u672a\u56e0\u725b\u5976\u800c\u51fa\u73b0\u4efb\u4f55\u75c7\u72b6\u3002<\/p>\n<\/section>\n<\/section>\n

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<\/section>\n<\/section>\n
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Fig 27.10 <\/span>\u8fd9\u4e2a\u7537\u5b69\u56e0\u63a5\u89e6\u575a\u679c\u800c\u8868\u73b0\u51fa\u4e86\u8840\u7ba1\u6027\u6c34\u80bf\u3002<\/span><\/p>\n<\/section>\n

\n
<\/section>\n<\/section>\n
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Fig 27.11<\/span>\u6025\u6027\u8368\u9ebb\u75b9\u662f\u4e00\u79cd\u53d1\u75d2\u7684\u76ae\u75b9\uff0c\u53ef\u7531\u8fc7\u654f\u5f15\u8d77\u3002\u5f53\u8368\u9ebb\u75b9\u6301\u7eed\u51e0\u5468\u4ee5\u4e0a\u65f6\uff0c\u5f88\u5c11\u4f1a\u7531\u8fc7\u654f\u5f15\u8d77\u3002<\/p>\n<\/section>\n

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<\/section>\n<\/section>\n
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Fig 27.12<\/span>\u7279\u5e94\u6027\u6e7f\u75b9\u4f1a\u5f15\u8d77\u589e\u539a\u7619\u75d2\u7684\u6d41\u884c\u6027\u76ae\u75b9\uff0c\u5c24\u5176\u4f1a\u5f71\u54cd\u819d\u76d6\u548c\u8098\u90e8\u7684\u5c48\u66f2\u3002<\/span><\/span><\/p>\n


<\/p>\n<\/section>\n

\n

\u75c5\u4eba\u7684\u6bcd\u4eb2\u4fdd\u7559\u4e86\u5de7\u514b\u529b\u68d2\u5305\u88c5\u7eb8\uff0c\u8fd9\u8bc1\u5b9e\u4e86\u5b83\u201c\u53ef\u80fd\u542b\u6709\u575a\u679c\u7684\u75d5\u8ff9\u201d\u3002\u9ad8\u5ea6\u8fc7\u654f\u7684\u4eba\u4f1a\u5bf9\u5c11\u91cf\u8fc7\u654f\u539f\u4ea7\u751f\u53cd\u5e94\uff0c\u8fd9\u4e9b\u8fc7\u654f\u539f\u53ef\u80fd\u662f\u5728\u52a0\u5de5\u8fc7\u7a0b\u4e2d\u6c61\u67d3\u65e0\u5bb3\u7684\u98df\u7269\u3002\u56e0\u4e3a\u8fd9\u4e2a\u75c5\u4eba\u4f3c\u4e4e\u5bf9\u575a\u679c\u8fc7\u654f\u539f\u975e\u5e38\u654f\u611f\uff0c\u6025\u8bca\u533b\u751f\u4e0d\u63a8\u8350\u75c5\u4eba\u8fdb\u884c\u76ae\u80a4\u70b9\u523a\u8bd5\u9a8c\u3002\u4ed6\u91c7\u96c6\u4e86\u8840\u6db2\u6837\u672c\uff0c\u5e76\u5b89\u6392\u60a3\u80052\u5468\u540e\u5728\u8fc7\u654f\u8bca\u6240\u5c31\u8bca\u3002<\/span><\/p>\n<\/section>\n

\n

\u7b2c\u4e00\u6b21\u8840\u6db2\u68c0\u6d4b\u663e\u793a\u8840\u6db2\u4e2d\u80a5\u5927\u7ec6\u80de\u7c7b\u80f0\u86cb\u767d\u9176\u6c34\u5e73\u5f88\u9ad8\u3002\u80a5\u5927\u7ec6\u80de\u7c7b\u80f0\u86cb\u767d\u9176\u901a\u5e38\u5728\u8840\u6db2\u4e2d\u8868\u73b0\u4e3a\u4f4e\u6c34\u5e73\uff0c\u5b83\u7684\u589e\u9ad8\u8868\u660e\u5728\u91c7\u96c6\u8840\u6db2\u6837\u672c\u4e4b\u524d\u53d1\u751f\u4e86\u80a5\u5927\u7ec6\u80de\u8131\u9897\u7c92\u3002\u7ed3\u5408\u75c5\u53f2\uff0c\u8fd9\u8bc1\u5b9e\u4e86\u8fc7\u654f\u53cd\u5e94\u5df2\u7ecf\u53d1\u751f(\u89c1BOX 22.1<\/span>)\u3002\u8840\u6db2\u68c0\u6d4b\u7ed3\u679c\u7684\u7b2c\u4e8c\u90e8\u5206\u662f\u7279\u5f02\u6027IgE\u68c0\u6d4b\u3002\u8fd9\u4e9b\u68c0\u6d4b\u6ca1\u6709\u68c0\u6d4b\u5230\u725b\u5976\u4e2d\u7684IgE\uff0c\u8fd9\u4e00\u70b9\u5f88\u91cd\u8981\uff0c\u56e0\u4e3a\u8fd9\u95f4\u63a5\u8bf4\u660e\u5de7\u514b\u529b\u68d2\u4e2d\u7684\u67d0\u4e9b\u6210\u5206\u53ef\u80fd\u662f\u8fc7\u654f\u539f\u3002\u7ed3\u679c\u7684\u7b2c\u4e8c\u90e8\u5206\u663e\u793a\uff0c\u8fd9\u4e2a\u7537\u5b69\u5bf9\u51e0\u79cd\u575a\u679c\u8fc7\u654f\u3002\u56e0\u4e3a\u6297\u539f\u4e4b\u95f4\u5b58\u5728\u4ea4\u53c9\u53cd\u5e94\uff0c\u6240\u4ee5\u5bf9\u51e0\u79cd\u575a\u679c\u4ea7\u751f\u53cd\u5e94\u662f\u5f88\u5e38\u89c1\u7684\u3002<\/p>\n

\u8fd9\u540d\u7537\u5b69\u9884\u9632\u8fc7\u654f\u7684\u4e00\u4e2a\u91cd\u8981\u63aa\u65bd\u662f\u964d\u4f4e\u4ee5\u540e\u63a5\u89e6\u575a\u679c\u7684\u98ce\u9669\uff0c\u8fd9\u5305\u62ec\u544a\u8beb\u7537\u5b69\u548c\u4ed6\u7684\u7236\u6bcd\u5e94\u8be5\u907f\u514d\u98df\u7528\u53ef\u80fd\u542b\u6709\u9690\u85cf\u575a\u679c\u7684\u98df\u7269\u3002\u7136\u800c\uff0c\u53cd\u590d\u63a5\u89e6\u8fc7\u654f\u539f\u662f\u5f88\u5e38\u89c1\u7684\uff0c\u8fd9\u540d\u60a3\u8005\u5f88\u6709\u53ef\u80fd\u4f1a\u51fa\u73b0\u5371\u53ca\u751f\u547d\u7684\u8fc7\u654f\u53cd\u5e94\u3002\u56e0\u6b64\uff0c\u4ed6\u5f97\u5230\u4e86\u4e00\u4e2a\u80be\u4e0a\u817a\u7d20\u808c\u8089\u6ce8\u5c04\u88c5\u7f6e\uff0c\u5e76\u63a5\u53d7\u4e86\u5728\u672a\u6765\u51fa\u73b0\u75c7\u72b6\u65f6\u4f7f\u7528\u8be5\u88c5\u7f6e\u7684\u57f9\u8bad\u3002\u808c\u8089\u6ce8\u5c04\u80be\u4e0a\u817a\u7d20\u662f\u6cbb\u7597\u8fc7\u654f\u53cd\u5e94\u7684\u91cd\u8981\u65b9\u6cd5\u3002\u80be\u4e0a\u817a\u7d20\u53ef\u4ee5\u9006\u8f6c\u8840\u7ba1\u8212\u5f20\u5e76\u7f29\u5c0f\u5185\u76ae\u7ec6\u80de\u4e4b\u95f4\u7684\u95f4\u9699\u3002\u6ce8\u5c04\u80be\u4e0a\u817a\u7d20\u540e\uff0c\u80bf\u80c0\u7684\u7ec4\u7ec7\u53ef\u6062\u590d\u6b63\u5e38\uff0c\u8840\u538b\u4e5f\u4f1a\u6062\u590d\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\u672c\u6587\u7531Oncolab\u5b9e\u9a8c\u5ba4\u5fae\u4fe1\u516c\u4f17\u53f7\u7ffb\u8bd1\u6574\u7406\u81eaImmunology for Medical Students\uff0c\u4ec5\u7528\u4e8e\u5b66\u4e60\u4ea4\u6d41\u4f7f\u7528\uff0c\u5982\u9700\u8d2d\u4e70\u539f\u7248\u4e66\u7c4d\u53ef\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8d2d\u4e70\u3002<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\u2014 THE  END \u2014<\/span><\/p>\n


<\/p>\n

\u6765\u6e90 | Immunology for Medical Students<\/span><\/section>\n
\u7ffb\u8bd1 |   \u848b\u4fca\u535a  \u9648\u6653\u610f \u9648\u8389\u8679 \u7f57\u4f73\u4f73<\/span><\/section>\n
\u7f16\u8f91\u6392\u7248 | \u9648\u6653\u610f<\/span><\/span><\/section>\n
\u521d\u5ba1 | \u5ed6\u5a9b \u4efb\u632f\u9633<\/span><\/span><\/section>\n
\u7ec8\u5ba1 | \u738b\u5764<\/span> \u8096\u5efa\u52c7<\/span><\/section>\n
\uff08\u8f6c\u8f7d\u8bf7\u4fdd\u7559\u6b64\u90e8\u5206\u5185\u5bb9\uff09<\/span><\/strong><\/section>\n

<\/section>\n

<\/section>\n

\u2589  \u5f80\u671f\u6587\u7ae0\u76ee\u5f55<\/strong><\/strong><\/p>\n

\u57fa\u7840\u514d\u75ab\u5b66\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c26\u7ae0\uff1a\u8d85\u654f\u53cd\u5e94<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c25\u7ae0\uff1a\u611f\u67d3\u548c\u75ab\u82d7<\/span><\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c24\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u4e2d\u7684\u7ec6\u80de\u56e0\u5b50<\/span><\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c23\u7ae0\uff1a\u708e\u75c7\u4e0e\u514d\u75ab<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c22\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u6740\u4f24\u529f\u80fd<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c21\u7ae0\uff1a\u541e\u566c\u7ec6\u80de<\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c20\u7ae0\uff1a\u56fa\u6709\u514d\u75ab\u7684\u9632\u5fa1\u4f5c\u7528<\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c19\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u751f\u7406\u529f\u80fd\u7b80\u8ff0<\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c18\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u8c03\u8282<\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c17\u7ae0\uff1a\u514d\u75ab\u8bb0\u5fc6\u4e0e\u6dcb\u5df4\u7ec6\u80de\u7a33\u6001<\/span><\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c16\u7ae0\uff1aT\u7ec6\u80de\u4e0e\u5176\u4ed6\u514d\u75ab\u7ec6\u80de\u95f4\u7684\u76f8\u4e92\u4f5c\u7528<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c15\u7ae0\uff1aT\u7ec6\u80de\u7684\u53d1\u80b2<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c14\u7ae0\uff1aB\u7ec6\u80de\u7684\u53d1\u80b2<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c13\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u5668\u5b98\u548c\u7ec4\u7ec7<\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c12\u7ae0\uff1a\u9020\u8840\u529f\u80fd-\u8840\u7ec6\u80de\u751f\u6210<\/a>
<\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c11\u7ae0\uff1a\u6dcb\u5df4\u7ec6\u80de\u6d3b\u5316<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c10\u7ae0\uff1a\u6297\u539f\u7684\u5904\u7406\u548c\u5448\u9012<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c9\u7ae0\uff1a\u6297\u539f\u8bc6\u522b\u7814\u7a76\u8fdb\u5c55<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c8\u7ae0\uff1a\u4e3b\u8981\u7ec4\u7ec7\u76f8\u5bb9\u6027\u590d\u5408\u7269MHC<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c7\u7ae0\uff1aT\u7ec6\u80de\u53d7\u4f53(TCR)\u6982\u8ff0<\/a>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c6\u7ae0\uff1a\u6297\u4f53\u591a\u6837\u6027<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c5\u7ae0\uff1a\u6297\u4f53-\u6297\u539f\u76f8\u4e92\u4f5c\u7528<\/a><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c4\u7ae0\uff1a\u6297\u539f\u548c\u6297\u4f53\u7ed3\u6784<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c3\u7ae0\uff1a\u6297\u539f\u8bc6\u522b<\/a><\/span><\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c2\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7684\u57fa\u672c\u6982\u5ff5\u548c\u7ec4\u6210<\/a><\/span>
<\/p>\n

\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c1\u7ae0\uff1a\u514d\u75ab\u7cfb\u7edf\u7b80\u4ecb<\/a><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c6\u7ae0\uff1a\u8c03\u8282\u6027T\u7ec6\u80de\u7684\u4f5c\u7528\u3001\u4f5c\u7528\u673a\u5236\u4ee5\u53ca\u5bf9\u764c\u75c7\u7684\u5f71\u54cd\uff08\u4e0b\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c6\u7ae0\uff1a\u8c03\u8282\u6027T\u7ec6\u80de\u7684\u4f5c\u7528\u3001\u4f5c\u7528\u673a\u5236\u4ee5\u53ca\u5bf9\u764c\u75c7\u7684\u5f71\u54cd\uff08\u4e0a\uff09<\/span><\/a><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c5\u7ae0\uff1aT\u7ec6\u80de\u6781\u5316\u7684\u79d8\u5bc6\uff08\u4e0b\uff09<\/span><\/a><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c5\u7ae0\uff1aT\u7ec6\u80de\u6781\u5316\u7684\u79d8\u5bc6\uff08\u4e0a\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c4\u7ae0\uff1a\u80bf\u7624\u4e2d\u7684\u7a81\u53d8\u8868\u4f4d\uff08\u4e0b\uff09<\/a><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c4\u7ae0\uff1a\u80bf\u7624\u4e2d\u7684\u7a81\u53d8\u8868\u4f4d\uff08\u4e0a\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c3\u7ae0\uff1aCD8+ T\u7ec6\u80de\u5728\u514d\u75ab\u6cbb\u7597\u3001\u653e\u7597\u548c\u5316\u7597\u4e2d\u7684\u4f5c\u7528\uff08\u4e0b\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c3\u7ae0\uff1aCD8+ T\u7ec6\u80de\u5728\u514d\u75ab\u6cbb\u7597\u3001\u653e\u7597\u548c\u5316\u7597\u4e2d\u7684\u4f5c\u7528\uff08\u4e0a\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c2\u7ae0\uff1a\u4eba\u7c7b\u80bf\u7624\u5fae\u73af\u5883\uff08\u4e0b\uff09<\/a><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c2\u7ae0\uff1a\u4eba\u7c7b\u80bf\u7624\u5fae\u73af\u5883\uff08\u4e0a\uff09<\/a>
<\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66-\u7b2c1\u7ae0\uff1a\u80bf\u7624\u514d\u75ab\u7b80\u53f2<\/span><\/a>
<\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66\u7cfb\u5217\u66f4\u65b0\u9884\u544a<\/span><\/a><\/p>\n

\u6587\u732e\u5206\u4eab\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u80bf\u7624\u4ee3\u8c22\u91cd\u7f16\u7a0b\u4e0e\u514d\u75ab\u5e94\u7b54<\/a>
<\/p>\n

\u5e74\u5ea6\u5de8\u732e\uff1a\u795e\u520aCA\u53d1\u5e03\u6700\u65b0\u764c\u75c7\u6570\u636e\uff1a\u5168\u74031000\u4e07\u4eba\u6b7b\u4e8e\u764c\u75c7\uff0c\u4e2d\u56fd\u5360\u6bd4\u8d853\u6210<\/a>
<\/p>\n

HLA-I\u5206\u5b50\u52a0\u5de5\u548c\u9012\u5448\u6297\u539f\u529f\u80fd\u53d7\u635f\u662f\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8010\u836f\u7684\u91cd\u8981\u539f\u56e0<\/a>
<\/p>\n

PD-1\/PD-L1\u963b\u65ad\u5242\u6cbb\u7597\u80bf\u7624\u7684\u7814\u7a76\u8fdb\u5c55\u4e0e\u9762\u4e34\u7684\u6311\u6218<\/a><\/span><\/p>\n

Immunity\uff1a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7684\u5341\u5927\u6311\u6218<\/span><\/a><\/p>\n

\u57fa\u4e8e\u5de8\u566c\u7ec6\u80de\u7684\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u65b9\u6cd5<\/span><\/a>
<\/p>\n

\u6700\u65b053\u5206\u7efc\u8ff0\uff1aMHC\u2160\u7c7b\u5206\u5b50\u4e0e\u80bf\u7624\u514d\u75ab\u76d1\u89c6\u548c\u514d\u75ab\u9003\u907f<\/a><\/p>\n

\u80bf\u7624\u6d78\u6da6DC\u7684\u8868\u578b\u548c\u529f\u80fd\u5dee\u5f02<\/span><\/a>
<\/p>\n

T\u7ec6\u80de\u8017\u7aed\uff08Exhaustion\uff09<\/span><\/a>
<\/p>\n

\u80bf\u7624\u76f8\u5173\u5de8\u566c\u7ec6\u80de\u53ca\u76f8\u5173\u9776\u5411\u6cbb\u7597<\/span><\/a>
<\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c7\u5929)-210608<\/a>
<\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c6\u5929)-210607<\/a>
<\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c5\u5929)-210605<\/a>
<\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c4\u5929)-210604<\/a><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c3\u5929)-210603<\/span><\/a>
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\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c1\u5929)-20210531<\/a><\/span><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0(\u7b2c2\u5929)-20210601<\/a><\/p>\n

Linux\u6700\u5f3a\u603b\u7ed3\uff01<\/span><\/a>
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TCGA\u514d\u75ab\u6d78\u6da6\u8bc4\u4ef7\u6570\u636e\u5e93<\/a>
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ggplot2|\u8be6\u89e3\u516b\u5927\u57fa\u672c\u7ed8\u56fe\u8981\u7d20<\/a>
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Python\u96c6\u6210\u5f00\u53d1\u73af\u5883PyCharm\u7684\u5b89\u88c5\u4e0e\u6fc0\u6d3b<\/a>
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Python\u53d1\u884c\u7248Anaconda\u7684\u5b89\u88c5\u4e0e\u4f7f\u7528<\/a><\/p>\n

\u57fa\u7840\u5b9e\u9a8c\u6280\u672f\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u6d41\u5f0f\u68c0\u6d4b\u7ec6\u80de\u603bROS-OncoLab\u5b9e\u9a8c\u5ba4<\/a><\/span>
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Annexin V\/PI\u67d3\u8272\u68c0\u6d4b\u7ec6\u80de\u51cb\u4ea1-OncoLab\u5b9e\u9a8c\u5ba4<\/a>
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\u514d\u75ab\u8367\u5149\u5b9e\u9a8c-OncoLab\u5b9e\u9a8c\u5ba4<\/a>
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WB\u64cd\u4f5c\u89c6\u9891-OncoLab\u5b9e\u9a8c\u5ba4<\/a><\/span><\/p>\n

QPCR\u5b9e\u9a8c\u64cd\u4f5c\u89c6\u9891-OncoLab\u5b9e\u9a8c\u5ba4<\/a>
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\u4eea\u5668\u64cd\u4f5c\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u5c0f\u52a8\u7269\u6d3b\u4f53\u5149\u5b66\u6210\u50cf\u7cfb\u7edf\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a>
<\/p>\n

\u8521\u53f8LSM800\u6fc0\u5149\u5171\u805a\u7126\u663e\u5fae\u955c\u64cd\u4f5c\u89c6\u9891-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a>
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IN Cell Analyzer2200\u9ad8\u5185\u6db5\u7ec6\u80de\u6210\u50cf\u5206\u6790\u7cfb\u7edf\u64cd\u4f5c\u6559\u7a0b-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a>
<\/p>\n

BD LSR Fortessa\u6d41\u5f0f-\u4e2d\u897f\u533b\u7ed3\u5408\u57fa\u7840\u7814\u7a76\u4e2d\u5fc3<\/a><\/span><\/p>\n

\u4f5c\u56fe\u6295\u7a3f\u9009\u520a\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

GraphPad+AI\u5236\u4f5c\u53ef\u53d1\u8868\u7ea7\u522b\u7684\u67f1\u72b6\u56fe-OncoLab\u5b9e\u9a8c\u5ba4<\/a>
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\u5982\u4f55\u4f7f\u7528ImageJ\u8fdb\u884c\u7ec6\u80de\u8367\u5149\u5b9a\u91cf<\/a>
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\u5982\u4f55\u4f7f\u7528Scrivener\u8fdb\u884c\u79d1\u6280\u8bba\u6587\u5199\u4f5c<\/a>
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Mendeley-\u6700\u597d\u7528\u7684\u6587\u732e\u9605\u8bfb\u7ba1\u7406\u8f6f\u4ef6\uff0c\u6ca1\u6709\u4e4b\u4e00<\/a>
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\u5982\u4f55\u9009\u62e9\u4e00\u4e2a\u5408\u9002\u7684\u6742\u5fd7\u8fdb\u884c\u6295\u7a3f\uff1f<\/a>
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PubMed\u4e2d\u5982\u4f55\u6309\u5f71\u54cd\u56e0\u5b50\u7b5b\u9009\u68c0\u7d22\u7ed3\u679c\u5e76\u663e\u793a\u5f71\u54cd\u56e0\u5b50\u53ca\u5206\u533a\uff1f<\/a>
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\u5982\u4f55\u4f7f\u7528EndNote\u8f6f\u4ef6\u63d2\u5165\u53c2\u8003\u6587\u732e\uff08\u96446813\u79cd\u6742\u5fd7\u53c2\u8003\u6587\u732e\u683c\u5f0f\u6587\u4ef6\uff09<\/a><\/span><\/p>\n

\u4e2d\u533b\u4e2d\u836f\u7cfb\u5217<\/strong><\/strong><\/span><\/p>\n

\u516b\u6bb5\u9526\uff08\u89c6\u9891\u7248+\u56fe\u7247\u7248\uff0c\u63a8\u8350\u6536\u85cf\uff09<\/span><\/a>
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\u4e2d\u6210\u836f\u4f20\u7edf\u65b9\u5242\u4ea4\u53c9\u68c0\u7d22\u6570\u636e\u5e93\u4f7f\u7528\u8bf4\u660e<\/a><\/span><\/p>\n

\u4e2d\u6210\u836f\u4f20\u7edf\u65b9\u5242\u4ea4\u53c9\u68c0\u7d22\u6570\u636e\u5e93\u89c6\u9891\u4ecb\u7ecd\uff08\u5b8c\u5168\u514d\u8d39\uff0c\u6c38\u4e0d\u6536\u8d39\uff09<\/a><\/span><\/p>\n


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\u5173\u6ce8\u672c\u53f7~<\/span><\/p>\n


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\u52a0\u5165\u8bfb\u8005\u4ea4\u6d41\u7fa4~<\/span><\/p>\n


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\u8d5e\u4e0e\u5728\u770b <\/span><\/section>\n
\u90fd\u9700\u8981<\/span><\/section>\n
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\u672c\u7bc7\u6587\u7ae0\u6765\u6e90\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7: OncoLab <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u5bfc \u8bfb \u672c\u7ae0\u4e3b\u8981\u8ba8\u8bba\u57fa\u56e0\u548c\u73af\u5883\u56e0\u7d20\u662f\u5982\u4f55\u8bf1\u5bfc\u514d\u75ab\u7cfb\u7edf\u5411TH2\u578b\u53cd\u5e94\u5206\u5316\u7684\u3002\u73af\u5883\u4e2d\u7684\u67d0\u4e9b\u53d8\u5316\u4f1a\u5bfc\u81f4\u4f53\u5185\u4ea7\u751f\u8fc7\u91cf\u7684…<\/p>\n","protected":false},"author":1,"featured_media":1903,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[64],"tags":[],"_links":{"self":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/1904"}],"collection":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/comments?post=1904"}],"version-history":[{"count":0,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/1904\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/media\/1903"}],"wp:attachment":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/media?parent=1904"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/categories?post=1904"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/tags?post=1904"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}