{"id":2596,"date":"2022-06-15T15:30:04","date_gmt":"2022-06-15T07:30:04","guid":{"rendered":"http:\/\/oncolab.cn\/index.php\/2022\/06\/15\/%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac30%e7%ab%a0%ef%bc%9a%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e7%96%be%e7%97%85%ef%bc%88iii%e5%9e%8b%e8%b6%85%e6%95%8f%e5%8f%8d%e5%ba%94\/"},"modified":"2022-06-15T15:30:04","modified_gmt":"2022-06-15T07:30:04","slug":"%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac30%e7%ab%a0%ef%bc%9a%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e7%96%be%e7%97%85%ef%bc%88iii%e5%9e%8b%e8%b6%85%e6%95%8f%e5%8f%8d%e5%ba%94","status":"publish","type":"post","link":"http:\/\/oncolab.cn\/index.php\/2022\/06\/15\/%e5%85%8d%e7%96%ab%e5%ad%a6%e6%8b%be%e9%81%97-%e7%ac%ac30%e7%ab%a0%ef%bc%9a%e5%85%8d%e7%96%ab%e5%a4%8d%e5%90%88%e7%89%a9%e7%96%be%e7%97%85%ef%bc%88iii%e5%9e%8b%e8%b6%85%e6%95%8f%e5%8f%8d%e5%ba%94\/","title":{"rendered":"\u514d\u75ab\u5b66\u62fe\u9057-\u7b2c30\u7ae0\uff1a\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\uff08III\u578b\u8d85\u654f\u53cd\u5e94\uff09"},"content":{"rendered":"
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\u672c\u7ae0\u8ba8\u8bba\u5728\u67d0\u4e9b\u60c5\u51b5\u4e0b\u6297\u4f53\u4e0e\u6297\u539f\u7ed3\u5408\u65f6\uff0c\u514d\u75ab\u590d\u5408\u7269<\/strong>\u662f\u5982\u4f55\u5f62\u6210\u7684\u3002\u8fd9\u4e9b\u6297\u539f\u53ef\u4ee5\u6765\u81ea\u611f\u67d3\u3001\u65e0\u5bb3\u7684\u73af\u5883\u7269\u8d28\u6216\u81ea\u8eab\u6297\u539f\u3002\u514d\u75ab\u590d\u5408\u7269\u901a\u5e38\u7531\u8865\u4f53\u7cfb\u7edf<\/strong>\u6e05\u9664\uff0c\u5982\u679c\u6ca1\u6709\u6e05\u9664\uff0c\u5219\u53ef\u80fd\u4f1a\u51fa\u73b0\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\uff0c\u519c\u6c11\u80ba<\/strong>\u548c\u963f\u745f\u6c0f\u53cd\u5e94<\/strong>\u90fd\u662f\u5c40\u90e8\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u7684\u4f8b\u5b50\u3002\u94fe\u7403\u83cc\u611f\u67d3\u540e\u7684\u80be\u5c0f\u7403\u80be\u708e<\/strong>\u4e5f\u662f\u4e00\u4e2a\u5faa\u73af\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\u7684\u5b9e\u4f8b\uff0c\u5728\u7b2c26\u7ae0\u4e2d\u5df2\u7ecf<\/span><\/span>\u63cf\u8ff0\u8fc7\u3002\u672c\u7ae0\u5c06\u66f4\u6df1\u5165\u5730\u7814\u7a76\u53e6\u4e00\u79cd\u7cfb\u7edf\u6027\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\uff0c\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae<\/strong>(SLE)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u514d\u75ab\u590d\u5408\u7269\u662f\u6297\u539f\u548c\u6297\u4f53\u7684\u590d\u5408\u7269\uff0c\u5b83\u4eec\u53ef\u4ee5\u5b9a\u4f4d\u4e8e\u6297\u539f\u4ea7\u751f\u7684\u90e8\u4f4d<\/strong>\uff0c\u4e5f\u53ef\u4ee5\u5728\u8840\u6db2\u4e2d\u5faa\u73af<\/strong>\u3002\u5b83\u4eec\u4f5c\u4e3a\u6b63\u5e38\u514d\u75ab\u53cd\u5e94\u7684\u4e00\u90e8\u5206\u4ea7\u751f\uff0c\u901a\u5e38\u901a\u8fc7\u8865\u4f53\u514d\u75ab\u673a\u5236\u88ab\u6e05\u9664\uff0c\u5982\u540e\u6587\u6240\u8ff0\u3002\u514d\u75ab\u590d\u5408\u7269\u5728\u8bb8\u591a\u60c5\u51b5\u4e0b\u4f1a\u5bfc\u81f4\u75be\u75c5\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u514d\u75ab\u590d\u5408\u7269\u4e2d\u7684\u6297\u539f<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u80fd\u591f\u5f62\u6210\u514d\u75ab\u590d\u5408\u7269\u7684\u6297\u539f<\/strong>\u5fc5\u987b\u662f\u591a\u4ef7\u7684<\/strong>\uff0c\u4e5f\u5c31\u662f\u8bf4\uff0c\u6bcf\u4e2a\u6297\u539f\u5206\u5b50\u5fc5\u987b\u80fd\u591f\u4e0e1\u4e2a\u4ee5\u4e0a\u7684\u6297\u4f53\u5206\u5b50\u7ed3\u5408\u3002\u5bf9\u4e8e\u514d\u75ab\u590d\u5408\u7269\u7684\u5f62\u6210\uff0c\u6297\u539f\u5fc5\u987b\u5b58\u5728\u8db3\u591f\u957f\u7684\u65f6\u95f4\u624d\u80fd\u5f15\u8d77\u6297\u4f53\u53cd\u5e94\u3002\u514d\u75ab\u590d\u5408\u7269\u901a\u5e38\u5728\u6297\u539f\u7565\u591a\u4e8e\u6297\u4f53<\/strong>\u65f6\u5f62\u6210(Fig30.1<\/span>)\u3002\u5f53\u6297\u539f\u662f\u4ee5\u4e0b\u4e09\u79cd\u6765\u6e90\u4e4b\u4e00\u65f6\uff0c\u5373\u53ef\u5f62\u6210\u514d\u75ab\u590d\u5408\u7269\uff1a(1)\u611f\u67d3\u6027\u6297\u539f\uff1b(2)\u65e0\u5bb3\u73af\u5883\u6297\u539f\uff1b(3)\u81ea\u8eab\u6297\u539f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u611f\u67d3\u6027\u6297\u539f<\/span><\/strong><\/p>\n<\/section>\n

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\u5927\u591a\u6570\u611f\u67d3\u90fd\u662f\u77ed\u6682\u7684\uff0c\u80fd\u591f\u901a\u8fc7\u514d\u75ab\u53cd\u5e94\u63a7\u5236\u3002\u7136\u800c\uff0c\u5373\u4f7f\u662f\u8fd9\u79cd\u80fd\u591f\u5feb\u901f\u63a7\u5236\u7684\u611f\u67d3\u4e2d\uff0c\u514d\u75ab\u590d\u5408\u7269\u4e5f\u53ef\u80fd\u5bfc\u81f4\u8d85\u654f\u53cd\u5e94<\/strong>\uff0c\u4f8b\u5982\u5728\u94fe\u7403\u83cc\u611f\u67d3\u4e4b\u540e\uff08<\/span>\u7b2c26\u7ae0\uff09<\/span><\/span>\u3002\u800c\u4e59\u809d\u7b49\u611f\u67d3\u5e76\u4e0d\u603b\u662f\u80fd\u5f97\u5230\u63a7\u5236\uff0c\u53ef\u80fd\u4f1a\u5bfc\u81f4\u8840\u6db2\u4e2d\u6297\u539f\u6c34\u5e73<\/strong>\u6301\u7eed\u8f83\u9ad8(\u6297\u539f\u8840\u75c7)\uff0c\u4ece\u800c\u5f15\u53d1\u66f4\u591a\u7684\u6162\u6027\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u65e0\u5bb3\u7684\u73af\u5883\u6297\u539f<\/strong><\/p>\n<\/section>\n

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\u65e0\u5bb3\u73af\u5883\u6297\u539f<\/strong>\u5982\u679c\u5c0f\u5230\u8db3\u4ee5\u8fdb\u5165\u7ec4\u7ec7<\/strong>\uff0c\u5c31\u80fd\u5f15\u53d1\u514d\u75ab\u7403\u86cb\u767dG(IgG<\/strong>)\u53cd\u5e94<\/strong>\u3002\u771f\u83cc\u5b62\u5b50\u662f\u4e00\u4e2a\u5f88\u597d\u7684\u4f8b\u5b50\uff0c\u5b83\u4f1a\u5f15\u8d77\u519c\u6c11\u80ba<\/strong>\u7684\u5c40\u90e8\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5(Box30.1<\/span>)\u3002\u836f\u7269\u4e5f\u662f\u73af\u5883\u6297\u539f\uff0c\u6709\u65f6\u4f1a\u5f15\u8d77\u5c40\u90e8\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\uff0c\u5982\u963f\u745f\u6c0f\u53cd\u5e94<\/strong>(Box30.2<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig30.1  <\/span>\u611f\u67d3\u671f\u95f4\u5f53\u6297\u4f53\u6c34\u5e73\u7565\u9ad8\u4e8e\u6297\u539f\u6c34\u5e73\u65f6\uff0c\u4ea7\u751f\u7684\u514d\u75ab\u590d\u5408\u7269\u6700\u591a\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u836f\u7269\u5f15\u8d77\u5faa\u73af\u514d\u75ab\u590d\u5408\u7269\u7684\u4ea7\u751f\uff0c\u8fd9\u4f1a\u5f15\u53d1\u8840\u6e05\u75c5\u3002\u8fd9\u4e2a\u540d\u5b57\u662f\u5728\u6297\u751f\u7d20\u51fa\u73b0\u4e4b\u524d\u521b\u9020\u51fa\u6765\u7684\uff0c\u5f53\u65f6\u611f\u67d3\u60a3\u8005\u88ab\u7ed9\u4e88\u514d\u75ab\u9a6c\u8840\u6e05\u3002\u5982\u4eca\uff0c\u8840\u6e05\u75c5<\/strong>\u51fa\u73b0\u7684\u6700\u5e38\u89c1\u539f\u56e0\u662f\u4f7f\u7528\u5c0f\u9f20<\/strong>\u5355\u514b\u9686\u6297\u4f53<\/strong>\u6cbb\u7597\u764c\u75c7\u6216\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5(\u7b2c36\u7ae0<\/span>)\u3002\u53cd\u590d\u63a5\u89e6\u4f1a\u5bfc\u81f4\u4ea7\u751f\u6297\u5c0f\u9f20\u6297\u4f53\u53ca\u5faa\u73af\u514d\u75ab\u590d\u5408\u7269<\/strong>\u3002\u8840\u6e05\u75c5\u4f1a\u5f15\u8d77\u53d1\u70e7\u3001\u76ae\u75b9\u548c\u5173\u8282\u75bc\u75db\u3002\u8fd9\u79cd\u75be\u75c5\u53ef\u901a\u8fc7\u5bf9\u5c0f\u9f20\u6297\u4f53\u8fdb\u884c\u57fa\u56e0\u5e72\u9884\u4eba\u4e3a\u89e3\u51b3\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u81ea\u8eab\u6297\u539f<\/strong>\u53ea\u6709\u5728\u81ea\u8eab\u6297\u4f53<\/strong>\u5b58\u5728\u7684\u60c5\u51b5\u4e0b\u624d\u80fd\u5f15\u8d77\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u3002DNA<\/strong>\u662f\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae<\/strong>\u7684\u6297\u539f(\u89c1Box30.3<\/span>)\uff0c\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae(SLE)\u662f\u6700\u5e38\u89c1<\/strong>\u7684\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u3002\u5f53\u7ec6\u80de\u6b7b\u4ea1\u65f6\uff0cDNA\u4f1a\u88ab\u91ca\u653e\u5230\u5faa\u73af\u4e2d\uff0c\u7279\u522b\u662f\u8d1f\u8d23\u6e05\u9664DNA<\/strong>\u7684\u5148\u5929\u514d\u75ab\u7cfb\u7edf\u673a\u5236\u6709\u7f3a\u9677<\/strong>\u7684\u8bdd(\u7b2c28\u7ae0<\/span>)\uff0c\u4e0d\u80fd\u8fc5\u901f\u6e05\u9664DNA\u4fbf\u4f1a\u5f15\u8d77\u6297\u4f53\u53cd\u5e94\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u514d\u75ab\u590d\u5408\u7269\u4e2d\u7684\u6297\u4f53<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u53ea\u6709\u5f53\u6297\u539f\u548c\u6297\u4f53\u7684\u6bd4\u4f8b<\/strong>\u6070\u5230\u597d\u5904\u65f6\uff0c\u624d\u4f1a\u5f62\u6210\u514d\u75ab\u590d\u5408\u7269\u3002\u6297\u4f53\u6c34\u5e73\u8f83\u4f4e\u65f6\uff0c\u6bcf\u4e2a\u6297\u539f\u5206\u5b50\u4e0e\u51e0\u4e2a\u514d\u75ab\u7403\u86cb\u767d\u5206\u5b50\u7ed3\u5408(\u89c1Fig30.1<\/span>)\u3002\u5f53\u6297\u4f53\u548c\u6297\u539f\u6c34\u5e73\u5927\u81f4\u76f8\u7b49\uff0c\u6216\u8005\u6297\u4f53\u6c34\u5e73\u7565\u9ad8\u65f6\uff0c\u4f1a\u5f62\u6210\u8f83\u5927\u7684\u590d\u5408\u7269<\/strong>\uff1b\u5f53\u6297\u4f53\u6c34\u5e73\u663e\u8457\u8d85\u8fc7\u6297\u539f\u65f6\uff0c\u5c06\u4f1a\u5f62\u6210\u5c0f\u7684\u590d\u5408\u7269<\/strong>\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u611f\u67d3\u671f\u95f4\uff0c\u514d\u75ab\u590d\u5408\u7269\u5728\u6297\u4f53\u6c34\u5e73\u5347\u9ad8\u7684\u6301\u7eed\u65f6\u95f4\u975e\u5e38\u77ed\u6682<\/strong>\uff0c\u514d\u75ab\u590d\u5408\u7269\u5f88\u5c11\u5728\u611f\u67d3\u671f\u95f4\u6301\u7eed\u5b58\u5728\uff0c\u53ea\u6709\u5728\u611f\u67d3\u4e0d\u80fd\u88ab\u6297\u4f53\u6e05\u9664\u65f6(\u4f8b\u5982\u809d\u708e\u75c5\u6bd2\u611f\u67d3)\u624d\u4f1a\u6301\u7eed\u6027\u5b58\u5728<\/strong>\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u6e05\u9664\u514d\u75ab\u590d\u5408\u7269<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u611f\u67d3\u8fc7\u7a0b\u4e2d\u4ea7\u751f\u6297\u4f53\u65f6\uff0c\u6b63\u5e38\u4eba\u4f53\u5185\u4f1a\u5f62\u6210\u514d\u75ab\u590d\u5408\u7269\u3002\u8fd9\u4e9b\u590d\u5408\u4f53\u5fc5\u987b\u88ab\u6e05\u9664\uff0c\u5426\u5219\u4ea7\u751f\u76f8\u5173\u81f4\u75c5\u673a\u5236\uff0c\u8865\u4f53<\/strong>\u53c2\u4e0e\u7684\u4e24\u79cd\u673a\u5236\u53ef\u4ee5\u6e05\u9664\u514d\u75ab\u590d\u5408\u7269<\/strong>(\u7b2c20\u7ae0<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig30.2<\/span>  \u514d\u75ab\u590d\u5408\u7269\u6e05\u9664\u60c5\u51b5\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u8865\u4f53\u5206\u89e3\u5927\u5206\u5b50\u53ef\u6eb6\u6027\u590d\u5408\u7269<\/span><\/strong><\/p>\n<\/section>\n

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\u6297\u539f\u514d\u75ab\u590d\u5408\u7269\u548c\u514d\u75ab\u7403\u86cb\u767d\u590d\u5408\u7269\u542b\u6709\u5927\u91cf\u7684\u514d\u75ab\u7403\u86cb\u767dFc<\/strong>\uff0c\u901a\u8fc7\u7ecf\u5178\u9014\u5f84\u6fc0\u6d3b\u8865\u4f53<\/strong>(Fig30.2<\/span>)\u3002\u5c0f\u5206\u5b50\u6210\u5206\uff0c\u7279\u522b\u662f\u6d3b\u5316\u7684\u8865\u4f53C3<\/strong>\u662f\u901a\u8fc7\u6fc0\u6d3b\u8865\u4f53\u9014\u5f84\u4ea7\u751f\u7684\uff0c\u8fd9\u4e9b\u5206\u5b50\u80fd\u591f\u63d2\u5165\u5e76\u5206\u89e3<\/strong>\u514d\u75ab\u590d\u5408\u7269\u7684\u7ed3\u6784\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u8865\u4f53\u53d7\u4f531\u5c06\u590d\u5408\u7269\u8f6c\u79fb\u81f3\u541e\u566c\u7ec6\u80de<\/strong><\/p>\n<\/section>\n

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\u7ea2\u7ec6\u80de<\/strong>\u5c06\u5faa\u73af\u514d\u75ab\u590d\u5408\u7269\u4ece\u7ec4\u7ec7\u548c\u8840\u6db2\u8f6c\u79fb\u5230\u809d\/\u813e\u541e\u566c\u7ec6\u80de<\/strong>\u5904\u3002\u7ea2\u7ec6\u80de\u8868\u8fbe\u8865\u4f53\u53d7\u4f531(CR1)<\/strong>\uff0c\u5b83\u662f\u6fc0\u6d3b\u7684\u8865\u4f53C3\u7684\u53d7\u4f53\u3002\u514d\u75ab\u590d\u5408\u7269\u4e0e\u7ea2\u7ec6\u80de\u4e0a\u7684\u8865\u4f53\u53d7\u4f53CR1\u7ed3\u5408\uff0c\u7136\u540e\u901a\u8fc7\u809d\u810f\u548c\u813e\u810f\u5faa\u73af\uff0c\u540c\u65f6\u523a\u6fc0\u5de8\u566c\u7ec6\u80de\u53d1\u6325\u541e\u566c<\/strong>\u529f\u80fd(\u89c1Fig30.2<\/span>)\u3002\u8fd9\u79cd\u673a\u5236\u975e\u5e38\u6709\u6548\uff0c\u5728\u51e0\u5206\u949f\u5185\u5b8c\u5168\u6e05\u9664\u5faa\u73af\u4e2d\u7684\u514d\u75ab\u590d\u5408\u7269\u3002\u6b64\u5916\uff0c\u7531\u4e8e\u813e\u810f\u662f\u8bb8\u591aB\u7ec6\u80de\u7684\u805a\u96c6\u5904\uff0c\u539f\u672c\u5b58\u5728\u4e8e\u5916\u5468\u7684\u6297\u539f\u88ab\u8fc5\u901f\u63d0\u5448\u7ed9B\u7ec6\u80de\uff0c\u4ee5\u4fc3\u8fdb\u6297\u4f53\u7684\u4ea7\u751f\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u8fd9\u4e9b\u514d\u75ab\u590d\u5408\u7269\u6e05\u9664\u673a\u5236\u53ef\u80fd\u5728\u514d\u75ab\u590d\u5408\u7269\u4ea7\u751f\u8fc7\u591a\u3001\u6301\u7eed\u4ea7\u751f<\/strong>\u7684\u60c5\u51b5\u4e0b\u8fbe\u5230\u9971\u548c\uff0c\u4f8b\u5982\uff0c\u5728\u6162\u6027\u611f\u67d3\u5f15\u8d77\u7684\u6297\u539f\u8840\u75c7\u4e2d\u3002\u4e00\u4e9b\u4e2a\u4f53\u7f3a\u4e4f\u8865\u4f53\uff0c\u5e76\u4e14\u5728\u4e0a\u8ff0\u673a\u5236\u4e2d\u4e0d\u80fd\u53d1\u6325\u4f5c\u7528\uff0c\u6613\u60a3\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5(\u89c1Box20.2<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u7684\u708e\u75c7\u673a\u5236<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u672a\u88ab\u8fc5\u901f\u6e05\u9664\u7684\u514d\u75ab\u590d\u5408\u7269\u901a\u8fc7\u6fc0\u6d3b\u5148\u5929\u514d\u75ab\u7cfb\u7edf<\/strong>\u7684\u6210\u5206\u800c\u9020\u6210\u635f\u5bb3(Fig30.3<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u514d\u75ab\u590d\u5408\u7269\u6fc0\u6d3b\u8865\u4f53\uff0c\u8fd9\u4e00\u8fc7\u7a0b\u6709\u52a9\u4e8e\u6e05\u9664\u590d\u5408\u7269\uff0c\u4f46\u4f1a\u4ea7\u751f\u4f4e\u5206\u5b50\u91cf\u8fc7\u654f\u6027\u6bd2\u7d20<\/strong>\uff0c\u589e\u52a0\u8840\u7ba1\u7684\u901a\u900f\u6027\uff0c\u4ecb\u5bfc\u767d\u7ec6\u80de\u7684\u8d8b\u5316\u4f5c\u7528\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u590d\u5408\u7269\u7ed3\u5408\u5e76\u6fc0\u6d3b\u4e2d\u6027\u7c92\u7ec6\u80de\u3001\u80a5\u5927\u7ec6\u80de\u548c\u8840\u5c0f\u677f\u7b49\u3002\u4e2d\u6027\u7c92\u7ec6\u80de<\/strong>\u548c\u80a5\u5927\u7ec6\u80de<\/strong>\u91ca\u653e\u86cb\u767d\u6c34\u89e3\u9176<\/strong>\uff0c\u7834\u574f\u8840\u7ba1\u5e76\u5f15\u53d1\u708e\u75c7\uff0c\u6d3b\u5316\u7684\u8840\u5c0f\u677f\u4e0e\u5185\u76ae\u7ec6\u80de\u7ed3\u5408\uff0c\u5f62\u6210\u8840\u6813\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5982\u679c\u6297\u539f\u4e3b\u8981\u5b58\u5728\u4e8e\u4e00\u4e2a\u90e8\u4f4d\uff0c\u514d\u75ab\u590d\u5408\u7269\u4f1a\u9020\u6210\u5c40\u90e8\u635f\u5bb3\uff0c\u4f8b\u5982\uff0c\u963f\u745f\u6c0f\u53cd\u5e94<\/strong>(\u89c1Box30.2<\/span>)\u548c\u519c\u6c11\u80ba<\/strong>(\u89c1Box30.1<\/span>)\u3002\u5f53\u6297\u539f\u8fc7\u591a\u65f6\u4ea7\u751f\u5c0f\u590d\u5408\u7269\u8fdb\u5165\u5faa\u73af\uff0c\u5f62\u6210\u5faa\u73af\u514d\u75ab\u590d\u5408\u7269\u3002\u5faa\u73af\u590d\u5408\u4f53\u5bf9\u8840\u7ba1\u9020\u6210\u635f\u4f24\uff0c\u7531\u6b64\u53ef\u80fd\u5bfc\u81f4\u8840\u7ba1\u58c1\u7684\u708e\u75c7<\/strong>\u3001\u8840\u7ba1\u7684\u95ed\u585e\u548c\u7f3a\u8840<\/strong>\u3002\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u662f\u5f15\u8d77\u8840\u7ba1\u708e\u75c7(\u8840\u7ba1\u708e)\u7684\u539f\u56e0\u4e4b\u4e00\u3002\u5faa\u73af\u514d\u75ab\u590d\u5408\u7269\u4f1a\u5bf9\u7279\u5b9a\u90e8\u4f4d\u9020\u6210\u635f\u5bb3\uff0c\u7279\u522b\u662f\u5173\u8282<\/strong>\u3001\u76ae\u80a4<\/strong>\u548c\u80be\u810f<\/strong>\u3002\u514d\u75ab\u590d\u5408\u7269\u53ef\u4ee5\u6c89\u79ef\u5728\u5173\u8282\u4e2d\uff0c\u5f15\u8d77\u6ed1\u819c\u708e\uff0c\u5bfc\u81f4\u75bc\u75db\u548c\u80bf\u80c0\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig30.3  <\/span>\u514d\u75ab\u590d\u5408\u7269\u901a\u8fc7\u6fc0\u6d3b\u5148\u5929\u514d\u75ab\u7cfb\u7edf\u9020\u6210\u635f\u4f24\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u80be\u810f\u4e2d\u7684\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u80be\u53d7\u7d2f\u4e8eIII\u578b\u8d85\u654f\u53cd\u5e94<\/strong>\u662f\u80be\u529f\u80fd\u8870\u7aed\u7684\u5e38\u89c1\u539f\u56e0\u3002\u80be\u810f\u7ecf\u5e38\u53d7\u5230\u5f71\u54cd\uff0c\u56e0\u4e3a\u80be\u5c0f\u7403\u7684\u8840\u538b\u6bd4\u4f53\u5faa\u73af\u4e2d\u7684\u8840\u538b\u9ad8\u56db\u500d\uff0c\u800c\u9ad8\u8840\u538b<\/strong>\u589e\u52a0\u4e86\u514d\u75ab\u590d\u5408\u7269\u5728\u8840\u7ba1\u58c1\u6c89\u79ef<\/strong>\u7684\u53ef\u80fd\u6027\u3002\u80be\u5c0f\u7403\u7ec6\u80de\u4f1a\u8868\u8fbe\u8865\u4f53\u53d7\u4f53CR1<\/strong>\uff0c\u53ef\u80fd\u6709\u5229\u4e8e\u514d\u75ab\u590d\u5408\u7269\u5728\u8be5\u90e8\u4f4d\u6c89\u79ef\u3002\u6ed1\u819c\u7ec6\u80de\u4e5f\u8868\u8fbeCR1\uff0c\u8fd9\u53ef\u80fd\u662f\u4e3a\u4ec0\u4e48\u5173\u8282\u4e5f\u7ecf\u5e38\u4e0e\u5faa\u73af\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\u6709\u5173\u7684\u539f\u56e0\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u80be\u810f\u4e2d\u7684\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\u53ef\u5bfc\u81f4\u4e24\u79cd\u4e34\u5e8a\u7efc\u5408\u5f81\uff1a\u80be\u75c5\u7efc\u5408\u5f81<\/strong>\uff0c\u86cb\u767d\u6e17\u5165\u5c3f\u6db2\uff0c\u51fa\u73b0\u6e10\u8fdb\u6027\u80be\u529f\u80fd\u8870\u7aed\uff1b\u80be\u708e<\/strong>\uff0c\u8fc5\u901f\u53d1\u751f\u80be\u529f\u80fd\u8870\u7aed\uff0c\u5c3f\u6db2\u4e2d\u6709\u8840\u6db2\u548c\u86cb\u767d\uff0c\u60a3\u8005\u8fd8\u4f1a\u6709\u9ad8\u8840\u538b\uff0c\u4e24\u79cd\u75be\u75c5\u90fd\u662f\u7531\u80be\u5c0f\u7403\u708e\u75c7(\u80be\u5c0f\u7403\u80be\u708e<\/strong>)\u5f15\u8d77\u7684\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u80be\u75c5\u7efc\u5408\u5f81\u4e2d\uff0c\u514d\u75ab\u590d\u5408\u7269\u6c89\u79ef\u5728\u80be\u5c0f\u7403\u57fa\u5e95\u819c<\/strong>\uff0c\u540c\u65f6\u6fc0\u6d3b\u8865\u4f53(Fig30.4<\/span>)\u3002\u8fd9\u901a\u5e38\u4f1a\u5bf9\u57fa\u5e95\u819c\u9020\u6210\u635f\u4f24\uff0c\u4ece\u800c\u4f7f\u86cb\u767d\u8d28\u6e17\u5165\u5230\u5c3f\u6db2\u4e2d\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u80be\u708e\u65f6\uff0c\u9664\u4e86\u8865\u4f53\u6d3b\u5316<\/strong>\u5916\uff0c\u8fd8\u4f1a\u5f15\u8d77\u7ec6\u80de\u6d78\u6da6<\/strong>\u3002\u4e2d\u6027\u7c92\u7ec6\u80de\u88ab\u52df\u96c6\u5230\u80be\u5c0f\u7403\uff0c\u7531\u6b64\u4ea7\u751f\u7684\u708e\u75c7\u5bfc\u81f4\u8840\u6db2\u548c\u86cb\u767d\u8d28\u6e17\u5165\u5230\u5c3f\u6db2\u4e2d\uff0c\u635f\u4f24\u80be\u810f\u6392\u6cc4\u6709\u6bd2\u4ee3\u8c22\u7269\u7684\u80fd\u529b\uff0c\u4ea7\u751f\u54ea\u79cd\u7c7b\u578b\u7684\u80be\u5c0f\u7403\u75c5\u53d8\u53d6\u51b3\u4e8e\u51e0\u4e2a\u56e0\u7d20\uff0c\u514d\u75ab\u590d\u5408\u7269\u7684\u5927\u5c0f\uff0c\u5b83\u4eec\u4ea7\u751f\u7684\u901f\u5ea6\uff0c\u4ee5\u53ca\u514d\u75ab\u590d\u5408\u7269\u7684\u6301\u7eed\u65f6\u95f4\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig30.4<\/span>  \u80be\u75c5\u7efc\u5408\u5f81\u3002A\u3001\u6b63\u5e38\u80be\u5c0f\u7403B\u3001\u590d\u5408\u4f53\u7f13\u6162\u5f62\u6210\uff0c\u5982\u5728\u4e59\u809d\u75c5\u6bd2\u611f\u67d3\u4e2dC\u3001\u590d\u5408\u4f53\u8fc5\u901f\u5f62\u6210\uff0c\u5982\u94fe\u7403\u83cc\u611f\u67d3\u540e\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u94fe\u7403\u83cc\u6027\u80be\u5c0f\u7403\u80be\u708e<\/strong>\uff08\u89c1Box26.3<\/span>\uff09\u4e2d\uff0c\u80be\u810f\u75be\u75c5\u8d77\u75c5\u6025\uff0c\u4f46\u6301\u7eed\u65f6\u95f4\u77ed\uff0c\u56e0\u4e3a\u611f\u67d3\u53d7\u5230\u514d\u75ab\u53cd\u5e94\u7684\u63a7\u5236\u3002\u5f53\u836f\u7269\u5f15\u8d77\u514d\u75ab\u590d\u5408\u7269\u4ecb\u5bfc\u7684\u80be\u75c5\u65f6\uff0c\u505c\u836f\u53ef\u4ee5\u6539\u5584\u80be\u529f\u80fd\u3002\u5728\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae<\/strong>\u4e2d\uff0c\u514d\u75ab\u590d\u5408\u7269\u542b\u6709\u81ea\u8eab\u6297\u539f\uff0c\u56e0\u6b64\u80be\u810f\u75be\u75c5\u662f\u6e10\u8fdb\u7684\uff0c\u4f46\u4e0d\u662f\u81ea\u9650\u6027\u7684(Box30.3<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u514d\u75ab\u590d\u5408\u4f53\u5e76\u4e0d\u662f\u80be\u5c0f\u7403\u80be\u708e\u7684\u552f\u4e00\u514d\u75ab\u5b66\u539f\u56e0\u3002\u5728GoodPasure\u7efc\u5408\u5f81(\u7b2c29\u7ae0<\/span>)\u548c\u514d\u75ab\u7403\u86cb\u767d\u8f7b\u94fe\u635f\u5bb3\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u4e2d\uff0c\u4e5f\u53ef\u80fd\u53d1\u751f\u80be\u810f\u635f\u4f24(\u7b2c35\u7ae0<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5b9e\u9a8c\u5ba4\u68c0\u67e5\u5728\u80be\u708e\u548c\u80be\u75c5\u7efc\u5408\u5f81\u7684\u7814\u7a76\u4e2d\u975e\u5e38\u91cd\u8981\u3002\u95f4\u63a5\u514d\u75ab\u8367\u5149<\/strong>\u7528\u4e8e\u5bfb\u627e\u4e0e\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\u6709\u5173\u7684\u6297\u4f53(\u5982\u6297DNA\u6297\u4f53<\/strong>)\u6216\u5176\u4ed6\u7c7b\u578b\u7684\u81ea\u8eab\u6297\u4f53(\u6297\u80be\u5c0f\u7403\u57fa\u5e95\u819c\u6297\u4f53<\/strong>)\u3002\u6709\u65f6\u6709\u5fc5\u8981\u5bf9\u80be\u6d3b\u68c0\u6807\u672c\u8fdb\u884c\u76f4\u63a5\u514d\u75ab\u8367\u5149\u68c0\u67e5\uff0c\u4ee5\u786e\u5b9a\u9020\u6210\u635f\u5bb3\u7684\u539f\u56e0\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u7684\u6cbb\u7597<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5728\u67d0\u4e9bIII\u578b\u8d85\u654f\u53cd\u5e94\u7684\u75c5\u4f8b\u4e2d\uff0c\u6297\u539f\u7684\u4ea7\u751f<\/strong>\u662f\u53ef\u4ee5\u907f\u514d\u7684\uff0c\u4f8b\u5982\uff0c\u519c\u592b\u80ba\u6216\u4e00\u4e9b\u836f\u7269\u548c\u75ab\u82d7\u5f15\u8d77\u7684\u8d85\u654f\u53cd\u5e94\u3002\u7136\u800c\uff0c\u81ea\u8eab\u6297\u539f(\u4f8b\u5982DNA)\u663e\u7136\u662f\u4e0d\u53ef\u4ee5\u907f\u514d\u7684\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u7531\u4e8e\u81ea\u8eab\u514d\u75ab\u75c5\u56e0\u800c\u5f15\u8d77\u7684\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u4e2d\uff0c\u76ae\u8d28\u7c7b\u56fa\u9187<\/strong>\u53ef\u4ee5\u963b\u65ad\u4e00\u4e9b\u6548\u5e94\u7ec6\u80de(\u5982\u4e2d\u6027\u7c92\u7ec6\u80de)\u9020\u6210\u7684<\/span>\u635f\u4f24\u3002\u73af\u78f7\u9170\u80fa\u662f\u4e00\u79cd\u70f7\u5316\u5242\uff0c\u4f1a\u6291\u5236DNA\u5408\u6210\uff0c\u963b\u6b62\u6dcb\u5df4\u7ec6\u80de\u7b49\u7ec6\u80de\u5feb\u901f\u589e\u6b96\u3002\u867d\u7136\u73af\u78f7\u9170\u80fa\u5bf9T\u7ec6\u80de\u6709\u4e00\u4e9b\u5f71\u54cd\uff0c\u4f46\u5b83\u4e3b\u8981\u662f\u6291\u5236B\u7ec6\u80de\u7684\u589e\u6b96\uff0c\u4ece\u800c\u964d\u4f4e\u81ea\u8eab\u6297\u4f53\u6c34\u5e73\uff0c\u73af\u78f7\u9170\u80fa<\/strong>\u5e38\u7528\u4e8e\u91cd\u75c7\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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BOX 30.1<\/span>\u519c\u6c11\u80ba<\/span><\/p>\n<\/section>\n<\/section>\n

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23\u5c81\uff0c\u519c\u6c11\uff0c\u5582\u5b8c\u725b\u540e\u591a\u6b21\u51fa\u73b0\u547c\u5438\u56f0\u96be\u3001\u54b3\u55fd\u3001\u8eab\u4f53\u4e0d\u9002\u548c\u53d1\u70e7\u3002\u4ed6\u662f\u5728\u63a5\u89e6\u5e72\u8349\u6570\u5c0f\u65f6\u540e\u51fa\u73b0\u4e86\u8fd9\u4e9b\u75c7\u72b6\uff0c\u6301\u7eed\u7ea62\u5929\u3002\u8840\u6db2\u6837\u672c\u663e\u793a\u4ed6\u6709\u9488\u5bf9\u9709\u83cc\u63d0\u53d6\u7269\u7684\u514d\u75ab\u7403\u86cb\u767dG(IgG)\u6297\u4f53\u3002\u6b64\u5916\uff0c\u8ba9\u4ed6\u63a5\u89e6\u9709\u83cc\u5b62\u5b505\u5c0f\u65f6\u540e\u4ed6\u7684\u75c7\u72b6\u518d\u6b21\u51fa\u73b0\uff0c\u6700\u7ec8\u786e\u8bca\u4e3a\u519c\u6c11\u80ba\u3002\u4ed6\u6309\u8981\u6c42\u5728\u5904\u7406\u5e72\u8349\u65f6\u901a\u8fc7\u8fc7\u6ee4\u9762\u7f69\u547c\u5438\uff0c\u75be\u75c5\u4e0d\u518d\u590d\u53d1\u3002<\/p>\n

\u519c\u6c11\u80ba\u60a3\u8005\u4f1a\u4ea7\u751f\u9488\u5bf9\u9709\u83cc\u5b62\u5b50\u4e2d\u86cb\u767d\u8d28\u7684IgG\u6297\u4f53\u3002\u63a5\u89e6\u5b62\u5b50\u540e\uff0c\u80ba\u90e8\u4f1a\u5f62\u6210\u514d\u75ab\u590d\u5408\u7269\u3002\u51e0\u4e2a\u5c0f\u65f6\u540e\uff0c\u8fd9\u4e9b\u514d\u75ab\u590d\u5408\u7269\u4f1a\u5728\u80ba\u6ce1\u5185\u5f15\u53d1\u708e\u75c7(Fig30.5<\/span>)\u3002\u8fd9\u4e00\u8fc7\u7a0b\u4e0d\u540c\u4e8eIgE\u4ecb\u5bfc\u7684\u8d85\u654f\u53cd\u5e94\uff0c\u540e\u8005\u5728\u63a5\u89e6\u6297\u539f\u65f6\u4f1a\u7acb\u5373\u51fa\u73b0\u75c7\u72b6\uff0c\u4e0d\u4f1a\u4ea7\u751f\u53d1\u70e7\u6216\u80ba\u90e8\u4ee5\u5916\u7684\u75c7\u72b6\u3002<\/span><\/p>\n<\/section>\n<\/section>\n

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Fig 30.5<\/span>  \u519c\u6c11\u80ba<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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BOX 30.2<\/span> \u963f\u745f\u6c0f\u53cd\u5e94<\/p>\n<\/section>\n<\/section>\n

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\u9189\u9152\u533b\u5b66\u751f\u817f\u90e8\u6495\u88c2\uff0c\u5728\u6025\u8bca\u79d1\u7f1d\u5408\u4f24\u53e3\u3002\u4ed6\u6700\u540e\u4e00\u6b21\u63a5\u79cd\u7834\u4f24\u98ce\u75ab\u82d7\u5927\u7ea6\u662f\u57285\u5e74\u524d\uff0c\u6839\u636e\u533b\u9662\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u4f1a\u5bf9\u4ed6\u8fdb\u884c\u7834\u4f24\u98ce\u5f3a\u5316\u75ab\u82d7\u63a5\u79cd\uff0c\u5728\u540e\u7eed\u6cbb\u7597\u8fdb\u884c\u76ae\u5185\u63a5\u79cd12\u5c0f\u65f6\u540e\uff0c\u63a5\u79cd\u75ab\u82d7\u90e8\u4f4d\u7684\u75bc\u75db\u75c5\u4f7f\u5f97\u60a3\u8005\u5728\u7761\u7720\u4e2d\u75db\u9192(Fig30.6<\/span>)\uff0c\u8fd9\u662f\u963f\u745f\u6c0f\u53cd\u5e94\u3002<\/p>\n

\u75ab\u82d7\u901a\u5e38\u662f\u808c\u8089\u6ce8\u5c04\uff0c\u8fd9\u6837\u6297\u539f\u5c31\u53ef\u4ee5\u6269\u6563\u5230\u6dcb\u5df4\u7cfb\u7edf\u3002\u76ae\u5185\u6ce8\u5c04\u7684\u6297\u539f\u4e0d\u80fd\u8fc5\u901f\u6269\u6563\uff0c\u56e0\u800c\u63a5\u79cd\u52a0\u5f3a\u7834\u4f24\u98ce\u75ab\u82d7\u4f7f\u5f97\u5c40\u90e8\u6297\u4f53\u6c34\u5e73\u8f83\u9ad8\uff0c\u6297\u539f\u548c\u672c\u8eab\u5b58\u5728\u7684\u6297\u4f53\u7ed3\u5408\uff0c\u5728\u539f\u4f4d\u5f62\u6210\u514d\u75ab\u590d\u5408\u7269\u5e76\u6fc0\u6d3b\u8865\u4f53\u3001\u80a5\u5927\u7ec6\u80de\u548c\u4e2d\u6027\u7c92\u7ec6\u80de\uff0c\u89e6\u53d1\u5c40\u90e8\u7684III\u578b\u8d85\u654f\u53cd\u5e94(Fig30.7<\/span>)\u3002<\/p>\n

\u963f\u745f\u6c0f\u53cd\u5e94\u7684\u53d1\u5c55\u901f\u5ea6\u6bd4I\u578b\u8d85\u654f\u53cd\u5e94\u6162\uff0c\u4f46\u6bd4IV\u578b\u8d85\u654f\u53cd\u5e94\u5feb\u3002\u56e0\u6b64\uff0c\u76ae\u80a4\u5bf9\u5916\u6e90\u6027\u6297\u539f\u53cd\u5e94\u7684\u5ef6\u8fdf\u4e3a\u4e86\u89e3\u4ecb\u8d28\u7684\u6027\u8d28\u63d0\u4f9b\u4e86\u91cd\u8981\u7ebf\u7d22\u3002\u514d\u75ab\u7403\u86cb\u767d\u4ecb\u5bfc\u7684\u53cd\u5e94\u57285\u5206\u949f\u5185\u53d1\u751f\uff0c\u514d\u75ab\u590d\u5408\u7269\u5f15\u8d77\u7684\u75c7\u72b6\u5728\u5927\u7ea612\u5c0f\u65f6\u540e\u51fa\u73b0\uff0c2\u81f33\u5929\u51fa\u73b0T\u7ec6\u80de\u635f\u4f24\u3002<\/p>\n<\/section>\n<\/section>\n

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Fig30.6 <\/span> \u963f\u745f\u6c0f\u53cd\u5e94\u9700\u898112\u5c0f\u65f6\u624d\u80fd\u51fa\u73b0\uff0c\u56e0\u4e3a\u514d\u75ab\u590d\u5408\u7269\u5fc5\u987b\u5728\u539f\u4f4d\u5f62\u6210\uff0c\u7136\u540e\u6fc0\u6d3b\u80a5\u5927\u7ec6\u80de\u548c\u4e2d\u6027\u7c92\u7ec6\u80de\u3002(\u4f26\u6566\u5723\u5df4\u585e\u6d1b\u7f2a\u533b\u9662\u63d0\u4f9b)<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig30.7<\/span>  \u8be5\u56fe\u663e\u793a\u4e86\u5bfc\u81f4\u963f\u745f\u6c0f\u53cd\u5e94\u7684\u7ec6\u80de\u6548\u5e94\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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BOX 30.3<\/span> \u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae<\/p>\n<\/section>\n<\/section>\n

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20\u5c81\uff0c\u5973\u6027\u56e0\u5173\u8282\u75bc\u75db\u548c\u76ae\u75b9\u88ab\u8bca\u65ad\u4e3a\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae(SLE\uff1b\u89c1Box28.3<\/span>)\u3002\u5982\u7b2c28\u7ae0<\/span>\u6240\u8ff0\uff0c\u95f4\u63a5\u514d\u75ab\u8367\u5149\u663e\u793a\u5979\u7684\u8840\u6db2\u4e2d\u542b\u6709\u6297\u6838\u6297\u4f53(\u89c1Fig28.14<\/span>)\uff0c\u800c\u9176\u8054\u514d\u75ab\u5438\u9644\u8bd5\u9a8c(ELISA)\u68c0\u6d4b\u663e\u793a\u5979\u7684DNA\u6297\u4f53\u6c34\u5e73\u5f88\u9ad8\u3002\u6700\u521d\u975e\u753e\u4f53\u6297\u708e\u836f\u80fd\u591f\u7f13\u89e3\u5979\u7684\u5173\u8282\u75bc\u75db\uff0c\u5f53\u5979\u907f\u514d\u5f3a\u70c8\u7684\u9633\u5149\u7167\u5c04\u65f6\u76ae\u75b9\u4f1a\u597d\u8f6c\u3002<\/p>\n

\u4e00\u5e74\u540e\uff0c\u5728\u98ce\u6e7f\u75c5\u79d1\uff0c\u5979\u63d0\u5230\u5173\u8282\u75bc\u75db\u66f4\u4e25\u91cd\u4e86\uff0c\u5e38\u89c4\u5c3f\u68c0\u63d0\u793a\u86cb\u767d\u8d28\u542b\u91cf\u5f88\u9ad8\uff0c\u80be\u529f\u80fd\u6b63\u5728\u6076\u5316\u3002\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u53ef\u5f15\u8d77\u4e00\u7cfb\u5217\u4e0d\u540c\u7684\u80be\u810f\u95ee\u9898\uff0c\u6240\u4ee5\u8981\u505a\u6d3b\u7ec4\u7ec7\u68c0\u67e5\u3002\u76f4\u63a5\u514d\u75ab\u8367\u5149\u663e\u793a\u8865\u4f53\u548c\u514d\u75ab\u7403\u86cb\u767d(Ig)G\u5728\u80be\u5c0f\u7403\u5185\u6c89\u79ef\uff0c\u4e0e\u514d\u75ab\u590d\u5408\u4f53\u75be\u75c5\u4e00\u81f4(<\/span>Fig30.8<\/span>)\u3002\u8fd9\u4e9b\u53d1\u73b0\u4e0e\u65e9\u5148\u7684\u76ae\u80a4\u6d3b\u68c0\u7ed3\u679c\u76f8\u4f3c(\u89c1<\/span>Fig28.13<\/span>)\u3002\u5e38\u89c4\u663e\u5fae\u955c\u68c0\u67e5\u663e\u793a\uff0c\u5979\u7684\u80be\u5c0f\u7403\u5185\u6709\u7ec6\u80de\u708e\u6027\u6d78\u6da6\u3002\u5982\u679c\u4e0d\u7ed9\u4e88\u6cbb\u7597\uff0cSLE\u4e2d\u8fd9\u7c7b\u80be\u810f\u75be\u75c5\u7684\u9884\u540e\u5f88\u5dee\u3002\u60a3\u8005\u63a5\u53d7\u4e86\u51e0\u4e2a\u7597\u7a0b\u7684\u9759\u8109\u6ce8\u5c04\u514d\u75ab\u6291\u5236\u836f\u7269\u73af\u78f7\u9170\u80fa\u6cbb\u7597\uff0c\u5979\u7684\u80be\u529f\u80fd\u548c\u5173\u8282\u95ee\u9898\u90fd\u6709\u76f8\u5f53\u5927\u7684\u6539\u5584\u3002<\/span><\/p>\n

\u5173\u8282\u3001\u76ae\u80a4\u548c\u80be\u810f\u53d7\u7d2f\u662f\u5178\u578b\u7684\u5faa\u73af\u514d\u75ab\u590d\u5408\u7269\u75be\u75c5\u3002\u9664\u4e86\u5173\u8282\u3001\u76ae\u80a4\u548c\u80be\u810f\u53d7\u7d2f\u5916\uff0c\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u8fd8\u4f1a\u5f71\u54cd\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u548c\u80ce\u76d8\uff0c\u540e\u8005\u4f1a\u5bfc\u81f4\u6d41\u4ea7\u3002<\/span><\/p>\n<\/section>\n<\/section>\n

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Fig30.8<\/span>  \u76f4\u63a5\u514d\u75ab\u8367\u5149\u73bb\u7247\u663e\u793a\u514d\u75ab\u7403\u86cb\u767dG(IgG)\u6c89\u79ef\u5728\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u60a3\u8005\u7684\u80be\u810f\u4e2d\u3002\u80be\u5c0f\u7403\u5df2\u7ecf\u201c\u4eae\u8d77\u6765\u201d\uff0c\u800c\u80be\u810f\u7684\u5176\u4f59\u90e8\u5206\u6ca1\u6709\u663e\u793a\u51fa\u4efb\u4f55IgG\u6c89\u79ef\u7684\u8bc1\u636e\u3002\u5bf9\u4e8e\u76f4\u63a5\u514d\u75ab\u8367\u5149\uff0c\u9700\u8981\u60a3\u8005\u7684\u7ec4\u7ec7\uff0c\u800cFig29.3\u662f\u5bf9\u60a3\u8005\u8840\u6e05\u8fdb\u884c\u7684\u95f4\u63a5\u514d\u75ab\u8367\u5149\uff0c\u4e0d\u9700\u8981\u60a3\u8005\u7684\u7ec4\u7ec7\u6d3b\u68c0\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u672c\u6587\u7531Oncolab\u5b9e\u9a8c\u5ba4\u5fae\u4fe1\u516c\u4f17\u53f7\u7ffb\u8bd1\u6574\u7406\u81eaImmunology for Medical Students\uff0c\u4ec5\u7528\u4e8e\u5b66\u4e60\u4ea4\u6d41\u4f7f\u7528\uff0c\u5982\u9700\u8d2d\u4e70\u539f\u7248\u4e66\u7c4d\u53ef\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8d2d\u4e70\u3002<\/span><\/p>\n


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\u2014 THE  END \u2014<\/span><\/p>\n


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\u6765\u6e90 | Immunology for Medical Students<\/span><\/section>\n
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\u7f16\u8f91\u6392\u7248 | \u7ae0\u9707<\/span><\/span><\/section>\n
\u521d\u5ba1 | \u848b\u4fca\u535a \u5b8b\u4e50<\/span><\/span><\/section>\n
\u7ec8\u5ba1 | \u8096\u5efa\u52c7 \u738b\u5764<\/span><\/section>\n
\uff08\u8f6c\u8f7d\u8bf7\u4fdd\u7559\u6b64\u90e8\u5206\u5185\u5bb9\uff09<\/span><\/section>\n

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\u2589  OncoLab\u5b9e\u9a8c\u5ba4\u7f51\u7ad9<\/strong><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u672c\u516c\u4f17\u53f7\u4e0a\u7684\u5f80\u671f\u6587\u7ae0\u540c\u6b65\u53d1\u5e03\u81f3\u5bf9\u5e94\u7f51\u7ad9OncoLab\u5b9e\u9a8c\u5ba4\u3002<\/p>\n

\u7f51\u7ad9\u81ea\u5e26\u68c0\u7d22\u529f\u80fd\uff0c\u53ef\u4ee5\u6839\u636e\u5173\u952e\u8bcd\u8fdb\u884c\u68c0\u7d22<\/span>\uff0c\u5e76\u4e14\u53ef\u4ee5\u6839\u636e\u65e5\u671f\u53ca\u5185\u5bb9\u5206\u7c7b<\/span>\u8fdb\u884c\u67e5\u770b ,\u5927\u5bb6\u53ef\u4ee5\u6536\u85cf\u65b9\u4fbf\u5728\u7535\u8111\u4e0a\u67e5\u770b\u3002<\/p>\n

\u7f51\u5740\u662f\uff1aoncolab.cn<\/span><\/strong><\/p>\n<\/section>\n

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\u2589  OncoLab\u5b66\u672f\u5bfc\u822a<\/strong><\/strong><\/p>\n

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\u672c\u7bc7\u6587\u7ae0\u6765\u6e90\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7: OncoLab <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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