{"id":3241,"date":"2023-11-05T00:09:46","date_gmt":"2023-11-04T16:09:46","guid":{"rendered":"http:\/\/oncolab.cn\/index.php\/2023\/11\/05\/cancer-cell%ef%bc%9a%e9%80%9a%e8%bf%87%e4%bd%93%e5%86%85%e5%b7%a5%e7%a8%8b%e5%8c%96%e5%b7%a8%e5%99%ac%e7%bb%86%e8%83%9e%e9%87%8d%e5%a1%91%e8%82%9d%e7%99%8c%e5%be%ae%e7%8e%af%e5%a2%83%e5%ae%9e%e7%8e%b0\/"},"modified":"2023-11-05T00:09:46","modified_gmt":"2023-11-04T16:09:46","slug":"cancer-cell%ef%bc%9a%e9%80%9a%e8%bf%87%e4%bd%93%e5%86%85%e5%b7%a5%e7%a8%8b%e5%8c%96%e5%b7%a8%e5%99%ac%e7%bb%86%e8%83%9e%e9%87%8d%e5%a1%91%e8%82%9d%e7%99%8c%e5%be%ae%e7%8e%af%e5%a2%83%e5%ae%9e%e7%8e%b0","status":"publish","type":"post","link":"http:\/\/oncolab.cn\/index.php\/2023\/11\/05\/cancer-cell%ef%bc%9a%e9%80%9a%e8%bf%87%e4%bd%93%e5%86%85%e5%b7%a5%e7%a8%8b%e5%8c%96%e5%b7%a8%e5%99%ac%e7%bb%86%e8%83%9e%e9%87%8d%e5%a1%91%e8%82%9d%e7%99%8c%e5%be%ae%e7%8e%af%e5%a2%83%e5%ae%9e%e7%8e%b0\/","title":{"rendered":"Cancer Cell\uff1a\u901a\u8fc7\u4f53\u5185\u5de5\u7a0b\u5316\u5de8\u566c\u7ec6\u80de\u91cd\u5851\u809d\u764c\u5fae\u73af\u5883\u5b9e\u73b0\u809d\u8f6c\u79fb\u7624\u6d88\u9664"},"content":{"rendered":"
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\u6742\u5fd7\u540d\u79f0<\/strong>\uff1aCancer Cell<\/span><\/p>\n

\u53d1\u8868\u65e5\u671f<\/strong>\uff1a2023.10.13<\/p>\n

DOI<\/strong>\uff1a10.1016\/j.ccell.2023.09.014.<\/p>\n

PubMed<\/strong>\uff1ahttps:\/\/pubmed.ncbi.nlm.nih.gov\/37863068<\/span><\/p>\n

\u5f71\u54cd\u56e0\u5b50<\/strong>\uff1a50.3<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u809d\u8f6c\u79fb\u7624\u5bf9\u5f53\u524d\u836f\u7269\u7597\u6cd5\uff0c\u5305\u62ec\u514d\u75ab\u7597\u6cd5\u7684\u53cd\u5e94\u5f80\u5f80\u8f83\u5dee\u3002\u6211\u4eec\u63cf\u8ff0\u4e86\u4e00\u4e2a\u6162\u75c5\u6bd2\u8f7d\u4f53(LV)\u5e73\u53f0\uff0c\u5176\u53ef\u7528\u4e8e\u9009\u62e9\u6027\u5730\u4fee\u6539\u809d\u5de8\u566c\u7ec6\u80de\uff0c\u5305\u62ec\u5e93\u666e\u5f17\u7ec6\u80de\u548c\u80bf\u7624\u76f8\u5173\u5de8\u566c\u7ec6\u80de(TAMs)\uff0c\u5e76\u5c06I\u578b\u5e72\u6270\u7d20(IFN\u03b1)\u4f20\u9012\u5230\u809d\u8f6c\u79fb\u7624\u3002\u57fa\u56e0\u578bIFN\u03b1\u7684\u8f93\u9001\u5ef6\u7f13\u4e86\u5c0f\u9f20\u4e2d\u7ed3\u80a0\u764c\u548c\u80f0\u817a\u5bfc\u7ba1\u817a\u764c\u809d\u8f6c\u79fb\u7624\u7684\u589e\u957f\u3002IFN\u03b1\u7684\u53cd\u5e94\u4e0e\u5de8\u566c\u7ec6\u80de\u7684\u514d\u75ab\u6fc0\u6d3b\u3001\u589e\u5f3a\u7684MHC-II\u9650\u5236\u6027\u6297\u539f\u9012\u5448\u548cCD8+ <\/sup>T\u7ec6\u80de\u75b2\u52b3\u7684\u51cf\u5c11\u76f8\u5173\u3002\u7136\u800c\uff0cIL-10\u4fe1\u53f7\u7684\u589e\u52a0\u3001\u7279\u6027\u663e\u793aI\u578b\u8c03\u8282\u6027T\u7ec6\u80de(Tr1)\u7279\u6027\u7684Eomes CD4+ <\/sup>T\u7ec6\u80de\u7684\u6269\u5c55\u548cCTLA-4\u7684\u8868\u8fbe\u4e0e\u6cbb\u7597\u62b5\u6297\u76f8\u5173\u3002\u901a\u8fc7\u7ed3\u5408CTLA-4\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u548cIFN\u03b1 LV\u8f93\u9001\u6765\u7cbe\u786e\u8c03\u63a7T\u7ec6\u80de\u529f\u80fd\uff0c\u6269\u5c55\u80bf\u7624\u53cd\u5e94\u6027T\u7ec6\u80de\uff0c\u5728\u5927\u591a\u6570\u5c0f\u9f20\u4e2d\u5b9e\u73b0\u4e86\u5b8c\u5168\u54cd\u5e94\u3002\u8fd9\u4e9b\u53d1\u73b0\u652f\u6301\u4e86\u4e00\u4e2a\u6709\u524d\u666f\u7684\u6cbb\u7597\u7b56\u7565\uff0c\u6709\u53ef\u80fd\u4e3a\u90a3\u4e9b\u6709\u672a\u6ee1\u8db3\u533b\u7597\u9700\u6c42\u7684\u60a3\u8005\u63d0\u4f9b\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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OncoLab\u516c\u4f17\u53f7\u5df2\u589e\u52a0\u671f\u520a\u67e5\u8be2\u529f\u80fd<\/span><\/strong>\uff0cSCI\u671f\u520a<\/strong><\/span>\u53ef\u67e5\u8be2\u671f\u520a\u540d\u79f0\u7f29\u5199\u3001ISSN\u520a\u53f7\u3001\u8fd1\u4e94\u5e74\u5f71\u54cd\u56e0\u5b50<\/strong>\u3001\u6700\u65b0WOS\u7684JCR\u5206\u533a<\/strong>\u3001\u6700\u65b0\u4e2d\u79d1\u9662\u5206\u533a<\/strong>\u4ee5\u53ca\u4e2d\u79d1\u9662\u671f\u520a\u9884\u8b66\u4fe1\u606f<\/strong>\uff1b<\/p>\n

\u4e2d\u6587\u671f\u520a<\/span><\/strong>\u53ef\u68c0\u7d22CSCD\u6838\u5fc3<\/strong>\u3001\u5317\u5927\u4e2d\u6587\u6838\u5fc3<\/strong>\u3001\u79d1\u6280\u6838\u5fc3<\/strong>\u6536\u5f55\u60c5\u51b5\uff1b<\/p>\n

\u5728\u516c\u4f17\u53f7\u5bf9\u8bdd\u6846\u53d1\u9001\u6742\u5fd7\u540d\u79f0<\/span><\/strong>\u5373\u53ef\u5feb\u901f\u68c0\u7d22\uff0c\u652f\u6301\u6a21\u7cca\u68c0\u7d22\uff0c\u6b22\u8fce\u4f7f\u7528\uff01<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u2014 THE  END \u2014<\/span><\/section>\n
\u6765\u6e90 | Cancer Cell<\/span><\/span><\/section>\n
\u7b5b\u9009\u7ffb\u8bd1\u6574\u7406 | \u738b\u5764<\/span><\/span><\/span><\/section>\n
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ACIR\u6587\u732e\u901f\u9012<\/span><\/a><\/p>\n

SCI\u8bba\u6587\u4f5c\u56fe<\/span><\/a><\/p>\n

SCI\u8bba\u6587\u5199\u4f5c\u53ca\u6295\u7a3f<\/span><\/a><\/p>\n

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RCIM\u4eea\u5668\u7b80\u4ecb\u53ca\u64cd\u4f5c\u89c6\u9891<\/a><\/span><\/p>\n

\u5e38\u7528\u7535\u8111\u8f6f\u4ef6\u4f7f\u7528\u6559\u7a0b<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u70b9\u4eae\u8d5e\u4e0e\u5728\u770b <\/span><\/p>\n

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\u672c\u7bc7\u6587\u7ae0\u6765\u6e90\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7: OncoLab <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u6742\u5fd7\u540d\u79f0\uff1aCancer Cell \u53d1\u8868\u65e5\u671f\uff1a2023.10.13 DOI\uff1a10.1016\/j.ccell.20…<\/p>\n","protected":false},"author":1,"featured_media":3239,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[63],"tags":[],"_links":{"self":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/3241"}],"collection":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/comments?post=3241"}],"version-history":[{"count":0,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/posts\/3241\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/media\/3239"}],"wp:attachment":[{"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/media?parent=3241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/categories?post=3241"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/oncolab.cn\/index.php\/wp-json\/wp\/v2\/tags?post=3241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}