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31.3 \u5f53\u524d\u7684\u548c\u65b0\u51fa\u73b0\u7684\u6cbb\u7597\u53cd\u5e94\u3001\u8010\u836f\u6027\u548c\u6bd2\u6027\u9884\u6d4b\u56e0\u7d20<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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31.3.3 \u57fa\u4e8e\u8840\u6db2\u7684\u6cbb\u7597\u53cd\u5e94\u9884\u6d4b\u56e0\u5b50<\/p>\n<\/section>\n

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31.3.4 \u6cbb\u7597\u53cd\u5e94\u7684\u65e0\u521b\u6027\u9884\u6d4b\u6307\u6807<\/p>\n<\/section>\n

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\u5f15\u5165\u4ee5\u514d\u75ab\u76f8\u5173\u53cd\u5e94\u6807\u51c6\uff08irRC\uff09\u4e3a\u57fa\u7840\u7684\u65b0\u8bc4\u4f30\u6807\u51c6\u8868\u660e\uff0c\u4f20\u7edf\u7684\u653e\u5c04\u5b66\u8bc4\u4f30\u5728\u68c0\u67e5\u70b9\u963b\u65ad\u6cbb\u7597\u7684\u764c\u75c7\u76d1\u6d4b\u4e2d\u5b58\u5728\u5c40\u9650\u6027\uff0c\u4e14\u5176\u4f5c\u4e3a\u53cd\u5e94\u9884\u6d4b\u56e0\u5b50\u7684\u80fd\u529b\u6709\u9650\u3002\u7136\u800c\uff0c\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u975e\u5178\u578b\u653e\u5c04\u5b66\u53cd\u5e94\u6a21\u5f0f\u5e76\u4e0d\u5e38\u89c1\u3002\u5728\u5e38\u89c4\u7684\u4e34\u5e8a\u5b9e\u8df5\u4e2d\uff0c\u653e\u5c04\u5b66\u53cd\u5e94\u901a\u5e38\u5728\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u6cbb\u7597\u5f00\u59cb\u540e10\u81f312\u5468\u624d\u80fd\u660e\u786e\u89c2\u5bdf\u5230\uff0c\u4e14\u4efb\u4f55\u65e9\u671f\u89c2\u5bdf\u5230\u7684\u53cd\u5e94\u90fd\u9700\u8981\u81f3\u5c114\u5468\u540e\u901a\u8fc7\u91cd\u590d\u626b\u63cf\u6765\u786e\u8ba4\u5176\u53ef\u9760\u6027\u3002\u5b9e\u9645\u4e0a\uff0c\u6709\u62a5\u9053\u6307\u51fa\u6cbb\u7597\u540e6\u81f39\u4e2a\u6708\u624d\u51fa\u73b0\u7684\u4e25\u91cd\u5ef6\u8fdf\u53cd\u5e94\u6848\u4f8b\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

PD-1\/PD-L\u8f74\uff0c\u5305\u62ec\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\u86cb\u767d1\uff08PD-1\uff09\u53ca\u5176\u914d\u4f53\uff08PD-L1\u548cPD-L2\uff09\uff0c\u662f\u7ef4\u6301\u5916\u5468\u8010\u53d7\u7684\u5173\u952e\u751f\u7406\u673a\u5236\u4e4b\u4e00\u3002\u8fd9\u4e00\u8f74\u662f\u63a7\u5236\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\u53cd\u5e94\u7684\u91cd\u8981\u8c03\u8282\u56e0\u5b50\uff0c\u4e0e\u8bb8\u591a\u5176\u4ed6\u7684\u6291\u5236\u6027\u53d7\u4f53\u8def\u5f84\u4e0d\u540c\uff0c\u5176\u529f\u80fd\u5728\u51e0\u4e4e\u6240\u6709\u7c7b\u578b\u7684\u708e\u75c7\u6761\u4ef6\u4e0b\u90fd\u88ab\u5e7f\u6cdb\u63cf\u8ff0\u3002PD-1\u4e3b\u8981\u5728\u6d3b\u5316\u7684T\u7ec6\u80de\u548cB\u7ec6\u80de\u4e0a\u8868\u8fbe\uff0c\u5176\u8868\u8fbe\u662f\u7531T\u7ec6\u80de\u53d7\u4f53\uff08TCR\uff09\u4f9d\u8d56\u7684\u6fc0\u6d3b\u8bf1\u5bfc\u7684\uff0c\u8868\u8fbe\u6c34\u5e73\u548c\u6301\u7eed\u65f6\u95f4\u5219\u53d6\u51b3\u4e8e\u523a\u6fc0\u7684\u6027\u8d28\u548c\u6301\u7eed\u6027\u3002PD-L1\u548cPD-L2\u901a\u5e38\u7531\u67d0\u4e9b\u5de8\u566c\u7ec6\u80de\u4e9a\u7fa4\u8868\u8fbe\uff0c\u4f46\u5728\u591a\u79cd\u708e\u75c7\u6761\u4ef6\u4e0b\uff0c\u4e5f\u53ef\u7531\u591a\u79cd\u708e\u75c7\u7ec6\u80de\u56e0\u5b50\u5728\u591a\u79cd\u9020\u8840\u53ca\u975e\u9020\u8840\u7ec6\u80de\u4e2d\u8bf1\u5bfc\u8868\u8fbe\u3002PD-1\/PD-L1\u8f74\u5728\u6291\u5236T\u7ec6\u80de\u7684\u5173\u952e\u529f\u80fd\u4e2d\u8d77\u4f5c\u7528\uff0c\u8fd9\u5305\u62ec\u9650\u5236\u7ec6\u80de\u56e0\u5b50\u7684\u4ea7\u751f\u3001\u6291\u5236\u7ec6\u80de\u7684\u589e\u6b96\u53ca\u7ec6\u80de\u6bd2\u6027\u9897\u7c92\u7684\u5f62\u6210\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u7136\u800c\uff0c\u6b63\u5728\u5f00\u53d1\u65b0\u7684\u57fa\u4e8e\u6210\u50cf\u7684\u6307\u6807\uff0c\u8fd9\u4e9b\u6307\u6807\u53ef\u80fd\u5728\u6cbb\u7597\u524d\u6216\u6cbb\u7597\u521d\u671f\u5c31\u80fd\u63d0\u4f9b\u8bca\u65ad\u548c\u6cbb\u7597\u7684\u91cd\u8981\u89c1\u89e3\uff0c\u6f5c\u5728\u5730\u4fc3\u8fdb\u5bf9\u90a3\u4e9b\u53ef\u80fd\u65e0\u6cd5\u4ece\u5f53\u524d\u6cbb\u7597\u65b9\u6848\u4e2d\u83b7\u76ca\u7684\u60a3\u8005\u8fdb\u884c\u5feb\u901f\u7684\u7ba1\u7406\u8c03\u6574\u3002\u4f8b\u5982\uff0c\u5728\u4e00\u7ec4\u63a5\u53d7ipilimumab\u548c\u6297\u8840\u7ba1\u751f\u6210\u836f\u7269\u8d1d\u4f10\u5355\u6297\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\uff0c\u5229\u7528Choi\u6807\u51c6\u7684\u653e\u5c04\u5b66\u8bc4\u4f30\u5305\u62ec\u4e86\u80bf\u7624\u5bc6\u5ea6\u7279\u5f81\uff1b\u9057\u61be\u7684\u662f\uff0c\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u80bf\u7624\u5bc6\u5ea6\u7684\u53d8\u5316\u5e76\u672a\u80fd\u6709\u6548\u9884\u6d4b\u6cbb\u7597\u53cd\u5e94\u3002\u800c\u5728\u6309Keynote-001\u65b9\u6848\u63a5\u53d7pembrolizumab\u5355\u6297\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\uff0c\u53d1\u73b0\u80bf\u7624\u7684\u5927\u5c0f\u548c\u5bc6\u5ea6\uff0c\u6216\u8005\u7ed3\u5408\u4f7f\u7528\u7684\u7efc\u5408\u6307\u6807\uff08\u5982Choi\u6216\u4fee\u6b63\u7684Choi\u6807\u51c6\uff09\u4e0e\u603b\u751f\u5b58\u7387\u6709\u5173\u3002<\/p>\n

\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fd9\u79cd\u5bc6\u5ea6\u7279\u5f81\u8bc4\u4f30\u4ecb\u7ecd\u4e86\u4e00\u79cd\u6bd4RECIST\u6216irRC\u66f4\u4e3a\u590d\u6742\u7684\u53cd\u5e94\u6a21\u5f0f\u5206\u6790\u65b9\u6cd5\uff0c\u4e3a\u672a\u6765\u5728\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u6cbb\u7597\u80cc\u666f\u4e0b\uff0c\u5229\u7528\u653e\u5c04\u5b66\/\u7ed3\u6784\u7279\u5f81\u4f5c\u4e3a\u6f5c\u5728\u7684\u9884\u540e\u6216\u9884\u6d4b\u56e0\u5b50\u7684\u7814\u7a76\u5f00\u8f9f\u4e86\u65b0\u9014\u5f84\u3002\u8fd9\u4e9b\u65b0\u53d1\u5c55\u6709\u671b\u4e3a\u4e34\u5e8a\u51b3\u7b56\u63d0\u4f9b\u66f4\u7cbe\u786e\u7684\u652f\u6301\uff0c\u7279\u522b\u662f\u5728\u8bc4\u4f30\u514d\u75ab\u6cbb\u7597\u7684\u6548\u679c\u65f6\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n

31.3.5 \u80a0\u9053\u5fae\u751f\u7269\u7ec4\u4f5c\u4e3a\u4e00\u79cd\u9884\u6d4b\u6027\u751f\u7269\u6807\u5fd7\u7269<\/p>\n<\/section>\n

\n
\n
\n

\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u7684\u4e00\u4e2a\u65b0\u5174\u9886\u57df\u662f\u7814\u7a76\u5fae\u751f\u7269\u7fa4\u7cfb\u53ca\u5176\u5bf9\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u53cd\u5e94\u7684\u5f71\u54cd\uff0c\u5176\u4e2d\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u7684\u4f5c\u7528\u5c24\u4e3a\u5173\u952e\u3002\u5728\u4e00\u9879\u5f00\u521b\u6027\u7684\u7814\u7a76\u4e2d\uff0c\u901a\u8fc7\u52a8\u7269\u6a21\u578b\u548c\u5bf9\u63a5\u53d7CTLA-4\u6291\u5236\u5242\u6cbb\u7597\u7684\u60a3\u8005\u8fdb\u884c\u7684\u7caa\u4fbf\u5fae\u751f\u7269\u79fb\u690d\u5b9e\u9a8c\uff0c\u53d1\u73b0\u4e86\u4e09\u4e2a\u5173\u952e\u89c2\u5bdf\u7ed3\u679c\uff1a\u9996\u5148\uff0c\u60a3\u8005\u5bf9\u6cbb\u7597\u7684\u53cd\u5e94\u663e\u8457\u4e0e\u80a0\u9053\u4e2d\u67d0\u4e9b\u7279\u5b9a\u7684\u62df\u6746\u83cc\u7269\u79cd\u7684\u4e30\u5bcc\u5ea6\u76f8\u5173\uff1b\u5176\u6b21\uff0c\u63a5\u53d7CTLA-4\u6291\u5236\u5242\u6cbb\u7597\u540e\u60a3\u8005\u7684\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u6210\u53d1\u751f\u4e86\u53d8\u5316\uff1b\u7b2c\u4e09\uff0cCTLA-4\u6291\u5236\u5242\u7684\u7597\u6548\u4f9d\u8d56\u4e8e\u5fae\u751f\u7269\u7279\u5f02\u6027T\u7ec6\u80de\u53cd\u5e94\u7684\u5b58\u5728\u3002<\/p>\n

\u5728\u53e6\u4e00\u9879\u7814\u7a76\u4e2d\uff0c\u53d1\u73b0\u80a0\u9053\u4e2d\u53cc\u6b67\u6746\u83cc\u7684\u4e30\u5bcc\u5ea6\u4e0e\u5c0f\u9f20\u66f4\u5f3a\u70c8\u7684\u81ea\u53d1\u6297\u80bf\u7624\u53cd\u5e94\u76f8\u5173\uff0c\u5176\u7279\u5b9a\u7684\u5fae\u751f\u7269\u201c\u8865\u5145\u5242\u201d\u4e0d\u4ec5\u5355\u72ec\u53d1\u6325\u4f5c\u7528\uff0c\u8fd8\u53ef\u4e0ePD-L1\u68c0\u67e5\u70b9\u963b\u65ad\u7597\u6cd5\u534f\u540c\u589e\u6548\u3002\u540c\u6837\uff0c\u63a5\u53d7PD-1\u6291\u5236\u5242\u6cbb\u7597\u7684\u60a3\u8005\u5728\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u6210\u548c\u591a\u6837\u6027\u65b9\u9762\u8868\u73b0\u51fa\u663e\u8457\u5dee\u5f02\uff0c\u8fd9\u5728\u6cbb\u7597\u6548\u679c\u597d\u4e0e\u5dee\u7684\u60a3\u8005\u4e2d\u5c24\u4e3a\u660e\u663e\u3002<\/p>\n

\u5c3d\u7ba1\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u4e0e\u73af\u5883\u3001\u996e\u98df\u3001\u5bbf\u4e3b\u514d\u75ab\u4ee5\u53ca\u6297\u80bf\u7624\u514d\u75ab\u4e4b\u95f4\u7684\u4ea4\u4e92\u4f5c\u7528\u5df2\u88ab\u5e7f\u6cdb\u8ba4\u8bc6\uff0c\u4f46\u8fd9\u4e9b\u76f8\u4e92\u4f5c\u7528\u5982\u4f55\u7cbe\u786e\u8c03\u8282\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7684\u53cd\u5e94\u673a\u5236\u4ecd\u5f85\u8fdb\u4e00\u6b65\u660e\u786e\u3002\u8fd9\u4e00\u9886\u57df\u7684\u6df1\u5165\u7814\u7a76\u53ef\u80fd\u63ed\u793a\u65b0\u7684\u6cbb\u7597\u76ee\u6807\uff0c\u4e3a\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u63d0\u4f9b\u66f4\u52a0\u4e2a\u6027\u5316\u548c\u6709\u6548\u7684\u7b56\u7565\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n

31.3.6 \u6bd2\u6027\u7684\u9884\u6d4b\u56e0\u5b50<\/p>\n<\/section>\n

\n
\n
\n

\u57fa\u4e8e\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u6cbb\u7597\u7684\u80bf\u7624\u7279\u5f02\u6027\u4e0d\u5b8c\u5168\uff0c\u975e\u9776\u5411\u514d\u75ab\u523a\u6fc0\u5bfc\u81f4\u7684\u514d\u75ab\u76f8\u5173\u6bd2\u6027\uff08\u514d\u75ab\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\uff0cirAEs\uff09\u662f\u5e38\u89c1\u7684\u3002\u6709\u65f6\uff0cirAEs\u7684\u51fa\u73b0\u88ab\u8ba4\u4e3a\u53ef\u80fd\u9884\u793a\u7740\u6297\u80bf\u7624\u514d\u75ab\u523a\u6fc0\u7684\u6d3b\u6027\uff1b\u7136\u800c\uff0c\u5728\u4f7f\u7528CTLA-4\u548cPD-1\u6cbb\u7597\u7684\u60c5\u51b5\u4e0b\uff0c\u5173\u4e8eirAEs\u7684\u53d1\u751f\u4e0e\u6297\u80bf\u7624\u4e34\u5e8a\u76ca\u5904\u4e4b\u95f4\u7684\u5173\u8054\uff0c\u4e0d\u540c\u80bf\u7624\u7c7b\u578b\u7684\u62a5\u544a\u5e38\u5e38\u663e\u793a\u51fa\u77db\u76fe\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n

\u9274\u4e8e\u8bb8\u591airAEs\u7684\u6f5c\u5728\u4e25\u91cd\u6027\uff0c\u8bc6\u522b\u53ef\u9760\u7684\u6bd2\u6027\u9884\u6d4b\u6807\u8bb0\u4e0e\u9884\u6d4b\u6cbb\u7597\u53cd\u5e94\u540c\u6837\u91cd\u8981\u3002\u7136\u800c\uff0c\u76ee\u524d\u5c1a\u672a\u786e\u5b9a\u4efb\u4f55\u6709\u6548\u7684\u9884\u6d4b\u6807\u8bb0\u3002\u4ece\u673a\u5236\u4e0a\u770b\uff0c\u4eba\u4eec\u8ba4\u4e3a\u5b58\u5728\u7684\u81ea\u8eab\u53cd\u5e94\u6027T\u7ec6\u80de\u514b\u9686\u53ef\u80fd\u56e0\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u800c\u88ab\u91cd\u65b0\u6fc0\u6d3b\uff0c\u5bfc\u81f4\u81ea\u8eab\u514d\u75ab\u6bd2\u6027\u3002\u8fd9\u4e9b\u514b\u9686\u5728\u6cbb\u7597\u524d\u53ef\u80fd\u53ea\u6709\u4f4e\u9891\u7387\u7684\u5b58\u5728\uff0c\u800c\u4e14\u5f53\u524d\u7f3a\u4e4f\u4ec5\u51ed\u5e8f\u5217\u4fe1\u606f\u5c31\u53ef\u9760\u9884\u6d4b\u7279\u5b9aT\u7ec6\u80de\u53d7\u4f53\u6297\u539f\u9776\u6807\u7684\u6280\u672f\uff0c\u8fd9\u4f7f\u5f97\u5bf9\u81ea\u8eab\u53cd\u5e94\u6027T\u7ec6\u80de\u7fa4\u4f53\u7684\u9884\u6d4b\u9274\u5b9a\u5b9e\u9645\u4e0a\u65e0\u6cd5\u5b9e\u73b0\u3002\u6b64\u5916\uff0c\u76ee\u524d\u5c1a\u4e0d\u6e05\u695a\u4e3a\u4f55\u4e00\u4e9b\u9884\u5148\u5b58\u5728\u4f46\u53d7\u5230\u6291\u5236\u7684\u514b\u9686\u4f1a\u88ab\u91cd\u65b0\u6fc0\u6d3b\uff0c\u800c\u5176\u4ed6\u514b\u9686\u5219\u4e0d\u4f1a\u3002<\/p>\n

\u5728\u9488\u5bf9CTLA-4\u6291\u5236\u5242\u6cbb\u7597\u7684\u60a3\u8005\u8fdb\u884c\u7684\u5168\u8840\u57fa\u56e0\u8868\u8fbe\u8c31\u7814\u7a76\u4e2d\uff0c\u867d\u7136\u5728\u6cbb\u7597\u4e2d\u7684\u6837\u672c\u4e2d\u8bc6\u522b\u4e86\u6f5c\u5728\u7684\u80c3\u80a0\u9053\u6bd2\u6027\u9884\u6d4b\u4fe1\u53f7\uff0c\u4f46\u672a\u80fd\u786e\u5b9a\u72ec\u7acb\u7684\u9884\u6d4b\u57fa\u56e0\u3002\u8fd9\u4e9b\u7814\u7a76\u7ed3\u679c\u63d0\u9192\u6211\u4eec\uff0c\u5728\u5f00\u53d1\u65b0\u7684\u514d\u75ab\u6cbb\u7597\u7b56\u7565\u65f6\uff0c\u9700\u8981\u8fdb\u4e00\u6b65\u63a2\u7d22\u548c\u7406\u89e3\u514d\u75ab\u76f8\u5173\u6bd2\u6027\u7684\u751f\u7269\u5b66\u57fa\u7840\uff0c\u4ee5\u6539\u5584\u60a3\u8005\u7ba1\u7406\u548c\u6cbb\u7597\u7ed3\u679c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
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<\/p>\n<\/section>\n<\/section>\n

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31.4 \u7cfb\u7edf\u514d\u75ab\u548c\u6297\u80bf\u7624\u514d\u75ab\u7684\u9759\u6001\u4e0e\u52a8\u6001\u8bc4\u4ef7<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4f20\u7edf\u7684\u764c\u75c7\u6cbb\u7597\u53cd\u5e94\u751f\u7269\u6807\u8bb0\u7269\u5206\u6790\u65b9\u6cd5\u4e3b\u8981\u4f9d\u8d56\u4e8e\u6cbb\u7597\u524d\u4ece\u7ec4\u7ec7\u6216\u8840\u6db2\u6837\u672c\u4e2d\u83b7\u53d6\u7684\u9759\u6001\u65f6\u95f4\u70b9\u6570\u636e\u3002\u7136\u800c\uff0c\u8fd9\u79cd\u65b9\u6cd5\u5b58\u5728\u5c40\u9650\u6027\uff0c\u5c24\u5176\u662f\u5f53\u6837\u672c\u88ab\u957f\u671f\u5b58\u6863\u65f6\uff0c\u53ef\u80fd\u7531\u4e8e\u57fa\u56e0\u7ec4\u7279\u5f81\u548c\u514d\u75ab\u5206\u6790\u7684\u6f14\u53d8\uff0c\u4f7f\u5f97\u751f\u7269\u6807\u8bb0\u7269\u7684\u51c6\u786e\u6027\u53d7\u5230\u5f71\u54cd\u3002\u8fd9\u4e0e\u6837\u672c\u7684\u7a7a\u95f4\u5f02\u8d28\u6027\u548c\u91c7\u6837\u8bef\u5dee\u7ed3\u5408\uff0c\u53ef\u80fd\u89e3\u91ca\u4e86\u50cfPD-L1\u8fd9\u6837\u7684\u9884\u5904\u7406\u751f\u7269\u6807\u5fd7\u7269\u4ec5\u5177\u6709\u9002\u4e2d\u7684\u9884\u6d4b\u4ef7\u503c\u3002\u6b64\u5916\uff0c\u7531\u4e8e\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\u5177\u6709\u52a8\u6001\u7279\u6027\uff0c\u4ec5\u9760\u5bf9\u9884\u5904\u7406\u6837\u672c\u7684\u9759\u6001\u8bc4\u4f30\u65e0\u6cd5\u5168\u9762\u628a\u63e1\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u968f\u7740\u8d8a\u6765\u8d8a\u591a\u7684\u7814\u7a76\u805a\u7126\u4e8e\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u53cd\u5e94\u7684\u9884\u6d4b\u751f\u7269\u6807\u8bb0\u7269\uff0c\u8d8a\u6765\u8d8a\u660e\u663e\u7684\u662f\uff0c\u5206\u6790\u65e9\u671f\u6cbb\u7597\u6837\u672c\u4e2d\u7684\u9002\u5e94\u6027\u514d\u75ab\u7279\u5f81\uff08\u6216\u4ece\u6cbb\u7597\u524d\u5230\u6cbb\u7597\u4e2d\u7684\u53d8\u5316\uff09\u5728\u9884\u6d4b\u80fd\u529b\u65b9\u9762\u53ef\u80fd\u8fdc\u80dc\u4e8e\u9759\u6001\u5206\u6790\uff0c\u8fd9\u53cd\u6620\u4e86\u80bf\u7624\u5fae\u73af\u5883\u7684\u52a8\u6001\u53d8\u5316(Fig.31.3<\/span>)\u3002\u6700\u8fd1\u7684\u7814\u7a76\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u8fd9\u4e00\u70b9\uff0c\u5176\u4e2d\u4e00\u9879\u7814\u7a76\u8868\u660e\uff0c\u901a\u8fc7\u514d\u75ab\u7ec4\u5316\u548c\u57fa\u56e0\u8868\u8fbe\u5206\u6790\u65e9\u671f\u6cbb\u7597\u6837\u672c\u5f97\u5230\u7684\u751f\u7269\u53cd\u5e94\u6807\u8bb0\u7269\u8fdc\u6bd4\u4ec5\u5206\u6790\u9884\u5904\u7406\u6837\u672c\u7684\u6807\u8bb0\u7269\u66f4\u4e3a\u5f3a\u5927\u3002\u5728\u5bf9\u57fa\u4e8e\u7ec4\u7ec7\u548c\u57fa\u4e8e\u8840\u6db2\u7684\u5206\u6790\u7684\u5176\u4ed6\u51e0\u9879\u7814\u7a76\u4e2d\u4e5f\u89c2\u5bdf\u5230\u4e86\u7c7b\u4f3c\u7684\u52a8\u6001\u53d1\u73b0\u3002<\/p>\n

\u7efc\u4e0a\u6240\u8ff0\uff0c\u8fd9\u4e9b\u7814\u7a76\u8868\u660e\uff0c\u5728\u514d\u75ab\u76d1\u6d4b\u4e2d\u5e94\u91c7\u7528\u65b0\u7684\u8303\u5f0f\uff0c\u5373\u5e38\u89c4\u8bc4\u4f30\u65e9\u671f\u6cbb\u7597\u53cd\u5e94\uff0c\u4ee5\u5e2e\u52a9\u6307\u5bfc\u6cbb\u7597\u7b56\u7565\u2014\u2014\u81f3\u5c11\u5728\u786e\u5b9a\u66f4\u6709\u6548\u7684\u9884\u5904\u7406\u751f\u7269\u6807\u8bb0\u7269\u4e4b\u524d\u5e94\u5982\u6b64(Fig.31.3<\/span>)\u3002\u91cd\u8981\u7684\u662f\uff0c\u8fd9\u6837\u7684\u5206\u6790\u5e94\u8be5\u88ab\u7eb3\u5165\u73b0\u4ee3\u4e34\u5e8a\u8bd5\u9a8c\u7684\u8bbe\u8ba1\u4e2d\u2014\u2014\u6700\u7ec8\u751a\u81f3\u53ef\u80fd\u6210\u4e3a\u6807\u51c6\u7684\u62a4\u7406\u6cbb\u7597\u6d41\u7a0b\u7684\u4e00\u90e8\u5206(Fig.31.4<\/span>)\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig 31.3<\/span> \uff08A\uff09\u52a8\u6001\u548c\u9759\u6001\u6807\u8bb0\u5bf9\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u963b\u65ad\u7684\u91cd\u8981\u6027\u3002\u5728\u4f20\u7edf\u7684\u764c\u75c7\u6cbb\u7597\u4e2d\uff0c\u4e00\u65e6\u8bca\u65ad\u51fa\u539f\u53d1\u80bf\u7624\uff0c\u901a\u5e38\u4f1a\u901a\u8fc7\u6709\u9650\u7684\u5206\u5b50\u5206\u6790\u548c\u80bf\u7624\u7ec4\u7ec7\u4ee5\u53ca\u53ef\u80fd\u7684\u8840\u6db2\u4e2d\u7684\u514d\u75ab\u56fe\u8c31\u8fdb\u884c\u80bf\u7624\u8bc4\u4f30\u3002\u6cbb\u7597\u901a\u5e38\u662f\u57fa\u4e8e\u7ecf\u9a8c\u7684\u975e\u4e2a\u6027\u5316\u65b9\u6848\uff0c\u60a3\u8005\u63a5\u53d7\u4e34\u5e8a\u8ddf\u8e2a\u548c\u53ef\u80fd\u7684\u653e\u5c04\u5b66\u968f\u8bbf\u3002\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u76f8\u5f53\u5927\u6bd4\u4f8b\u7684\u60a3\u8005\u4f1a\u7ecf\u5386\u75be\u75c5\u590d\u53d1\uff0c\u5e76\u63a5\u53d7\u975e\u4e2a\u6027\u5316\u7684\u4e8c\u6b21\u6cbb\u7597\u2014\u2014\u901a\u5e38\u5728\u6700\u5c11\u6216\u6ca1\u6709\u751f\u7269\u6807\u5fd7\u7269\u8bc4\u4f30\u7684\u60c5\u51b5\u4e0b\u8fdb\u884c\u3002\u540c\u6837\uff0c\u53cd\u5e94\u7684\u60a3\u8005\u5f88\u5c11\uff0c\u5927\u591a\u6570\u60a3\u8005\u6700\u7ec8\u7ecf\u5386\u4e86\u6cbb\u7597\u9003\u9038\uff0c\u603b\u4f53\u7ed3\u679c\u8f83\u5dee\u3002<\/span>(B) \u5728\u764c\u75c7\u6cbb\u7597\u7684\u521b\u65b0\u65b9\u6cd5\u4e2d\uff0c\u901a\u8fc7\u5728\u6cbb\u7597\u524d\u8fdb\u884c\u5e7f\u6cdb\u7684\u5206\u5b50\u548c\u514d\u75ab\u56fe\u8c31\u5206\u6790\uff0c\u6765\u6269\u5c55\u539f\u53d1\u80bf\u7624\u7684\u7ec4\u7ec7\u5b66\u8bca\u65ad\u3002\u9009\u62e9\u4e2a\u6027\u5316\u7684\u521d\u7ea7\u6cbb\u7597\u65b9\u6848\u662f\u57fa\u4e8e\u8fd9\u4e9b\u8be6\u7ec6\u7684\u89c1\u89e3\uff0c\u4ece\u800c\u4f7f\u66f4\u9ad8\u6bd4\u4f8b\u7684\u60a3\u8005\u5b9e\u73b0\u957f\u671f\u75be\u75c5\u63a7\u5236\u3002\u53ea\u6709\u5c11\u90e8\u5206\u60a3\u8005\u53d1\u751f\u75be\u75c5\u590d\u53d1\uff0c\u6b64\u65f6\uff0c\u4e2a\u6027\u5316\u7684\u4e8c\u6b21\u6cbb\u7597\u65b9\u6cd5\u88ab\u7528\u6765\u7ed3\u5408\u590d\u53d1\u80bf\u7624\u7684\u5206\u5b50\u548c\u514d\u75ab\u56fe\u8c31\u4ee5\u53ca\u80bf\u7624\u548c\u8840\u6db2\u7684\u6cbb\u7597\u54cd\u5e94\u56fe\u8c31\u3002\u8f83\u5c11\u7684\u60a3\u8005\u7ecf\u5386\u75be\u75c5\u9003\u9038\uff0c\u5f53\u8fd9\u79cd\u60c5\u51b5\u786e\u5b9e\u53d1\u751f\u65f6\uff0c\u57fa\u4e8e\u66f4\u7cbe\u7ec6\u5316\u7684\u6cbb\u7597\u7b56\u7565\uff0c\u5bf9\u4e2a\u6027\u5316\u65b9\u6cd5\u7684\u54cd\u5e94\u66f4\u9ad8\u3002\u901a\u8fc7\u8fd9\u79cd\u65b9\u6cd5\uff0c\u6cbb\u7597\u6548\u679c\u4e0d\u4f73\u7684\u60a3\u8005\u975e\u5e38\u5c11\u89c1\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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Fig 31.4<\/span> \u5c06\u751f\u7269\u6807\u8bb0\u7269\u7eb3\u5165\u80bf\u7624\u514d\u75ab\u5b66\u4e34\u5e8a\u8bd5\u9a8c\u7684\u8bbe\u8ba1\uff0c\u53ef\u4ee5\u663e\u8457\u63d0\u9ad8\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6548\u7387\u548c\u6548\u679c\u3002\u73b0\u6709\u7684\u751f\u7269\u6807\u8bb0\u7269\u80fd\u591f\u7528\u4e8e\u6307\u5bfc\u60a3\u8005\u9009\u62e9\u548c\/\u6216\u767b\u8bb0\u53c2\u52a0\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u5176\u4e2d\u5df2\u9a8c\u8bc1\u7684\u751f\u7269\u6807\u8bb0\u7269\u63d0\u4f9b\u9884\u6d4b\u6027\u4fe1\u606f\u4ee5\u6307\u5bfc\u6cbb\u7597\u65b9\u6848\u7684\u9009\u62e9\u3002\u6b64\u5916\uff0c\u9884\u540e\u548c\u9884\u6d4b\u6027\u6807\u8bb0\u7269\u53ef\u7528\u4e8e\u5bf9\u53c2\u8bd5\u8005\u7684\u5165\u9009\u8fdb\u884c\u5206\u5c42\uff0c\u4f18\u5316\u6cbb\u7597\u8f6c\u6362\u548c\u4e34\u5e8a\u7ed3\u679c\u3002<\/span>\u4e3a\u4fdd\u6301\u6cbb\u7597\u7684”\u672a\u77e5\u6027”\u5e76\u5bfb\u627e\u4e0e\u80bf\u7624\u7ec4\u7ec7\u5b66\u7c7b\u578b\u65e0\u5173\u7684\u53cd\u5e94\u751f\u7269\u6807\u8bb0\u7269\uff0c\u9700\u8981\u62db\u52df\u591a\u6837\u5316\u7684\u4eba\u7fa4\u8fdb\u884c\u8bd5\u9a8c\u3002\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5bf9\u63a5\u53d7\u6cbb\u7597\u7684\u60a3\u8005\u5728\u6cbb\u7597\u524d\u548c\u6cbb\u7597\u671f\u95f4\u8fdb\u884c\u751f\u7269\u6837\u672c\u91c7\u96c6\uff0c\u5c24\u5176\u5f3a\u8c03\u7eb5\u5411\u91c7\u6837\uff0c\u4ee5\u4fbf\u6536\u96c6\u5173\u4e8e\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u52a8\u6001\u53d8\u5316\u7684\u91cd\u8981\u4fe1\u606f\uff0c\u5305\u62ec\u6297\u836f\u6027\u7684\u53d1\u5c55\u3002<\/span>\u91c7\u7528\u9002\u5e94\u6027\u8bbe\u8ba1\u7ed3\u5408”\u5373\u65f6”\u751f\u7269\u6807\u8bb0\u7269\u76d1\u6d4b\uff0c\u53ef\u4ee5\u4fc3\u8fdb\u5bf9\u90a3\u4e9b\u4f3c\u4e4e\u4e0d\u592a\u53ef\u80fd\u6709\u53cd\u5e94\u7684\u60a3\u8005\u8fdb\u884c\u65e9\u671f\u3001\u57fa\u4e8e\u751f\u7269\u6807\u8bb0\u7269\u7684\u6cbb\u7597\u8c03\u6574\u3002\u8fbe\u5230\u76f8\u5173\u7684\u4e34\u5e8a\u7ec8\u70b9\u540e\uff0c\u53ef\u80fd\u4f1a\u8fdb\u884c\u4e34\u5e8a\u548c\u751f\u7269\u6807\u8bb0\u7269\u7ed3\u679c\u7684\u5173\u8054\u5206\u6790\uff0c\u4ece\u800c\u4f5c\u51fa\u63a5\u53d7\u6216\u62d2\u7edd\u7279\u5b9a\u751f\u7269\u6807\u8bb0\u7269\u3001\u6cbb\u7597\u65b9\u6848\u6216\u4e24\u8005\u7684\u5173\u952e\u51b3\u7b56\u3002\u5728\u51fa\u73b0\u4e0d\u4e00\u81f4\u7684\u60c5\u51b5\u65f6\uff0c\u751f\u7269\u6807\u8bb0\u7269\u53ef\u4ee5\u9884\u6d4b\u6cbb\u7597\u5931\u8d25\uff0c\u5e76\u53ef\u80fd\u968f\u540e\u88ab\u786e\u8ba4\u4e3a\u7528\u4e8e\u53cd\u5411\u6cbb\u7597\u5206\u914d\u7684\u751f\u7269\u6807\u8bb0\u7269\u3002<\/span>\u5bf9\u4e8e\u672a\u80fd\u4ece\u521d\u59cb\u6cbb\u7597\u83b7\u76ca\u7684\u60a3\u8005\uff0c\u6839\u636e\u751f\u7269\u6807\u5fd7\u7269\u4fe1\u606f\uff0c\u53ef\u4ee5\u7279\u522b\u6216\u9002\u5e94\u6027\u5730\u9009\u62e9\u4e8c\u6b21\u6216\u540e\u7eed\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u4ee5\u671f\u63d0\u9ad8\u6cbb\u7597\u7684\u4e2a\u4f53\u5316\u548c\u6210\u529f\u7387\u3002\u8fd9\u79cd\u65b9\u6cd5\u4e0d\u4ec5\u589e\u5f3a\u4e86\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7b56\u7565\u6027\uff0c\u8fd8\u53ef\u80fd\u63d0\u9ad8\u60a3\u8005\u7684\u751f\u5b58\u8d28\u91cf\u548c\u603b\u4f53\u751f\u5b58\u7387\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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31.5 \u5c06\u9884\u6d4b\u56e0\u7d20\u7eb3\u5165\u4e34\u5e8a\u8bd5\u9a8c\u548c\u62a4\u7406\u6cbb\u7597\u6807\u51c6<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u6301\u7eed\u4f18\u5316\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u7b56\u7565\u7684\u6210\u529f\u5c06\u4f9d\u8d56\u4e8e\u6700\u5927\u5316\u7597\u6548\u548c\u6700\u5c0f\u5316\u514d\u75ab\u76f8\u5173\u6bd2\u6027\uff0c\u8fd9\u4e24\u8005\u90fd\u9700\u5bc6\u5207\u5173\u6ce8\u751f\u7269\u6807\u8bb0\u7269\u7684\u53d1\u73b0\u3002\u5f53\u524d\uff0c\u7531\u4e8e\u7f3a\u4e4f\u53ef\u9760\u7684\u9884\u6d4b\u65e0\u5e94\u7b54\u6307\u6807\uff0c\u73b0\u5b9e\u4e16\u754c\u4e2d\u7684\u4e34\u5e8a\u5b9e\u8df5\u8fd8\u65e0\u6cd5\u50cf\u4e34\u5e8a\u8bd5\u9a8c\u90a3\u6837\u7cbe\u51c6\u5730\u5b9a\u4f4d\u201c\u5f3a\u5e94\u7b54\u8005\u201d\u3002\u56e0\u6b64\uff0c\u9700\u8981\u5927\u91cf\u52aa\u529b\u901a\u8fc7\u6b63\u5728\u8fdb\u884c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6765\u6269\u5c55\u514d\u75ab\u6cbb\u7597\u7684\u9002\u7528\u8303\u56f4\uff0c\u800c\u4e0d\u4ec5\u4ec5\u662f\u96c6\u4e2d\u4e8e\u5df2\u77e5\u53ef\u80fd\u83b7\u76ca\u8f83\u5927\u7684\u60a3\u8005\u7fa4\u4f53\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5c06\u751f\u7269\u6807\u8bb0\u7269\u7684\u53d1\u73b0\u7eb3\u5165\u8fd9\u4e9b\u4e34\u5e8a\u8bd5\u9a8c\u65b9\u6848\u65f6\uff0c\u9700\u8981\u8003\u8651\u51e0\u4e2a\u5173\u952e\u56e0\u7d20\uff1a(1)\u6240\u83b7\u5f97\u7684\u751f\u7269\u6807\u8bb0\u7269\u5e94\u80fd\u53cd\u6620\u53d7\u6cbb\u7597\u5f71\u54cd\u7684\u751f\u7269\u9694\u5ba4\uff1b(2)\u8003\u8651\u836f\u7269\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u836f\u6548\u5b66\u7279\u6027\uff0c\u5408\u7406\u5b89\u6392\u91cd\u590d\u6837\u672c\u91c7\u96c6\u7684\u65f6\u95f4\u548c\u9891\u7387\uff0c\u5e76\u786e\u4fdd\u8fd9\u4e9b\u5236\u5242\u80fd\u6709\u6548\u6e17\u900f\u5230\u5404\u4e2a\u4e0d\u540c\u7684\u7ec4\u7ec7\u9694\u5ba4\uff1b(3)\u6536\u96c6\u751f\u7269\u6807\u8bb0\u7269\u7684\u53ef\u884c\u6027\u4e0e\u60a3\u8005\u7684\u63a5\u53d7\u7a0b\u5ea6\uff1b\u4ee5\u53ca(4)\u5c06\u751f\u7269\u6807\u8bb0\u7269\u7684\u7ed3\u679c\u6574\u5408\u5230\u6cbb\u7597\u65b9\u6848\u7684\u8bbe\u8ba1\u4e0e\u8c03\u6574\u4e2d\u7684\u53ef\u80fd\u6027(Fig.31.4<\/span>)\u3002\u8fd9\u79cd\u7efc\u5408\u65b9\u6cd5\u5c06\u63a8\u52a8\u66f4\u4e3a\u7cbe\u786e\u548c\u4e2a\u6027\u5316\u7684\u6cbb\u7597\u7b56\u7565\uff0c\u4ece\u800c\u63d0\u9ad8\u6cbb\u7597\u6548\u679c\u5e76\u964d\u4f4e\u4e0d\u826f\u53cd\u5e94\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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31.6 \u603b\u7ed3\u548c\u7ed3\u8bba<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u968f\u7740\u7814\u7a76\u7684\u6df1\u5165\uff0c\u8d8a\u6765\u8d8a\u660e\u663e\u6211\u4eec\u9700\u8981\u4e00\u79cd\u7efc\u5408\u7684\u65b9\u6cd5\u548c\u7cbe\u786e\u7684\u9884\u6d4b\u6a21\u578b\u6765\u6307\u5bfc\u6cbb\u7597\u3002\u8fd9\u5305\u62ec\u6d4b\u91cf\u80bf\u7624\u548c\u8840\u6db2\u6837\u672c\u5728\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u7684\u7eb5\u5411\u9002\u5e94\u6027\u53cd\u5e94\u3002\u8fd9\u4e9b\u6982\u5ff5\u4e0d\u4ec5\u5e94\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5f97\u5230\u5e7f\u6cdb\u63a5\u53d7\uff0c\u4e5f\u5e94\u5728\u6807\u51c6\u62a4\u7406\u7684\u6cbb\u7597\u8bbe\u7f6e\u4e2d\u5f97\u5230\u5145\u5206\u8003\u8651\u3002\u901a\u8fc7\u8fd9\u79cd\u65b9\u6cd5\uff0c\u6211\u4eec\u53ef\u4ee5\u5728\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u6cbb\u7597\u7684\u80cc\u666f\u4e0b\u5b9e\u73b0\u6700\u4f18\u7684\u6cbb\u7597\u548c\u76d1\u6d4b\u7b56\u7565\uff0c\u4ece\u800c\u4e3a\u60a3\u8005\u63d0\u4f9b\u6700\u4f73\u7684\u6cbb\u7597\u6548\u679c\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u672c\u6587\u7531Oncolab\u5fae\u4fe1\u516c\u4f17\u53f7\u7ffb\u8bd1\u6574\u7406\u81eaOncoimmunology: A Practical Guide for Cancer Immunotherapy\uff0c\u4ec5\u7528\u4e8e\u5b66\u4e60\u4ea4\u6d41\u4f7f\u7528\uff0c\u5982\u9700\u8d2d\u4e70\u539f\u7248\u4e66\u7c4d\u53ef\u70b9\u51fb\u9605\u8bfb\u539f\u6587\u8d2d\u4e70\u3002<\/span>
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\u2014 THE  END \u2014<\/span><\/p>\n


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\u6765\u6e90 | Oncoimmunology: A Practical Guide <\/span><\/p>\n

for Cancer Immunotherapy<\/span><\/p>\n

\u521d\u7a3f\u7ffb\u8bd1 | \u6e29\u946b<\/span><\/p>\n

\u56fe\u6587\u6392\u7248 | \u90ed\u5b50 \u675c\u8f7b\u677e<\/span><\/span><\/p>\n

\u5ba1\u6838\u4fee\u6539 | \u738b\u5764<\/span><\/p>\n

\uff08\u8f6c\u8f7d\u8bf7\u4fdd\u7559\u6b64\u90e8\u5206\u5185\u5bb9\uff09<\/span><\/strong><\/p>\n

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\u2589  \u5f80\u671f\u63a8\u9001\u5408\u8f91<\/strong><\/strong><\/section>\n
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\u80bf\u7624\u514d\u75ab\u5b66\u6700\u65b0\u6587\u732e<\/span><\/a>
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\u514d\u75ab\u5b66\u62fe\u9057\u7cfb\u5217<\/a><\/span><\/p>\n

\u80bf\u7624\u514d\u75ab\u5b66\u7cfb\u5217<\/span><\/a><\/p>\n

ACIR\u6587\u732e\u901f\u9012<\/span><\/a><\/p>\n

SCI\u8bba\u6587\u4f5c\u56fe<\/span><\/a><\/p>\n

SCI\u8bba\u6587\u5199\u4f5c\u53ca\u6295\u7a3f<\/span><\/a><\/p>\n

\u751f\u4fe1\u5165\u95e8\u5b66\u4e60\u7b14\u8bb0<\/span><\/a><\/p>\n

R\u8bed\u8a00\u57fa\u7840\u4e0e\u5355\u7ec6\u80de\u5206\u6790\u5b9e\u6218\u89c6\u9891\u8bfe\u7a0b<\/span><\/a><\/p>\n

\u751f\u7269\u5b66\u5b9e\u9a8c\u6280\u672f\u53ca\u5e38\u7528\u8f6f\u4ef6<\/span><\/a><\/p>\n

RCIM\u4eea\u5668\u7b80\u4ecb\u53ca\u64cd\u4f5c\u89c6\u9891<\/a><\/span><\/p>\n

\u5e38\u7528\u7535\u8111\u8f6f\u4ef6\u4f7f\u7528\u6559\u7a0b<\/a><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5173\u6ce8\u672c\u53f7~<\/span>
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\u52a0\u5165\u8bfb\u8005\u4ea4\u6d41\u7fa4~<\/span><\/p>\n

\uff08\u6dfb\u52a0\u8bf7\u5907\u6ce8\u5355\u4f4d\u59d3\u540d\uff09<\/span><\/p>\n


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\u52a0\u5165\u77e5\u8bc6\u661f\u7403~<\/span><\/p>\n


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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u70b9\u4eae\u8d5e\u4e0e\u5728\u770b <\/span><\/p>\n

\u8ba9\u66f4\u591a\u4eba\u770b\u5230<\/span><\/p>\n

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\n

\u672c\u7bc7\u6587\u7ae0\u6765\u6e90\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7: OncoLab <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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